Risques disproportionnés pour la santé mentale chez les femmes autistes : une revue rapide avec des synthèses quantitatives et narratives

Titre original en anglais : Disproportionate mental health risks in autistic females: A rapid review with quantitative and narrative syntheses

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Lacroix, A., Tzang, C. C., Yu, J., Jacob, B. K., Alexandrovsky, M., Winge-Breen, A., Rodak, T., & Lai, M. C. (2025). Disproportionate mental health risks in autistic females: A rapid review with quantitative and narrative syntheses. Frontiers in Neuroendocrinology, 80, 101229. https://doi.org/10.1016/j.yfrne.2025.101229

Date de publication: 14/12/2025 Ajout dans AutiHub: 04/07/2026 Type: Article Langue de l’article: Anglais
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Auteurs

Auteur·ices des publications
8
Auteur·ices de la publication identifié·es comme autistes
2 / 8 (25,0 %)
  1. Adeline Lacroix *
  2. Chih-Chen Tzang
  3. Jiakun Yu
  4. Benjamin Koshy Jacob
  1. Mishel Alexandrovsky *
  2. Anna Winge-Breen
  3. Terri Rodak
  4. Meng-Chuan Lai

Résumé

Les troubles de santé mentale sont très fréquents chez les personnes autistes, mais une synthèse actualisée des données de prévalence stratifiées selon le sexe, des facteurs contributifs et des stratégies de soutien fait défaut. Pour combler cette lacune dans les connaissances, nous avons mené une revue rapide en utilisant les lignes directrices PRISMA-ScR. Les bases de données MEDLINE, CINAHL et PsycINFO ont été interrogées afin d’identifier des études (2004-2024) incluant des participantes ayant un diagnostic clinique d’autisme et portant sur la santé mentale. Parmi les 8 420 références examinées, 218 répondaient aux critères d’inclusion. Une synthèse quantitative exploratoire des études fondées sur la population et sur les registres a révélé des taux plus élevés de troubles de santé mentale chez les femmes autistes que chez les hommes autistes pour les troubles anxieux, de l’humeur, alimentaires, obsessionnels-compulsifs, psychotiques et de la personnalité. La synthèse narrative a identifié des facteurs modérateurs, notamment la physiologie liée au sexe, les expériences genrées, l’âge, l’âge au diagnostic d’autisme, les caractéristiques de l’autisme et les affections concomitantes. Les mécanismes biologiques et sociaux interagissent probablement en tant que facteurs contributifs. Les graves conséquences d’une mauvaise santé mentale soulignent la nécessité d’approches adaptées tenant compte des profils spécifiques des femmes autistes.

Mental health conditions are highly prevalent among autistic people, but an updated synthesis of sex-stratified prevalence data, contributing factors, and support strategies is lacking.To address this knowledge gap, we conducted a rapid review utilizing PRISMA-ScR guidelines. MEDLINE, CINAHL, and PsycINFO databases were searched for studies (2004-2024) including female participants with a clinical autism diagnosis, and with a focus on mental health. Of 8,420 records screened, 218 met inclusion criteria. An exploratory quantitative synthesis of population-based and registry-based studies revealed higher rates of mental health conditions in autistic females than males for anxiety, mood, eating, obsessive-compulsive, psychotic, and personality disorders. Narrative synthesis identified moderating factors, including sex-related physiology, gendered experiences, age, age at autism diagnosis, autism characteristics, and co-occurring conditions. Biological and social mechanisms likely interact as contributing factors. Severe consequences of poor mental health underscore the need for tailored approaches accounting for the specific profiles of autistic females.

Bibliographie citée par cette référence

Les références citées sont importées depuis des sources externes de métadonnées lorsqu’elles sont disponibles. La liste peut être partielle.

Vue d’ensemble de l’inclusion dans la bibliographie

Ces indicateurs décrivent la bibliographie citée importée pour cette publication. Les métriques de références citées utilisent le total des références citées comme dénominateur. Les métriques d’auteurices cité·es indiquent si elles utilisent toutes les occurrences d’auteurices cité·es ou seulement les occurrences rattachées à des auteurices déjà intégré·es à la base de données AutiHub. Ils utilisent les rattachements mis en cache entre les auteurices cité·es et les auteurices intégré·es à la base de données AutiHub. Dernier calcul : 16/08/2026 11:30.

Références citées
270
Nombre total de références citées intégrées pour cette publication.
Références citées avec un·e auteur·ice identifié·e comme autiste
14 / 270 (5,2 %)
Occurrences d’auteur·ices cité·es identifié·es comme autistes
24 / 1441 (1,7 %)
Parmi les occurrences rattachées à des auteurices intégré·es à la base de données AutiHub : 24 / 421 (5,7 %). Auteurices cité·es distinct·es identifié·es comme autistes : 19 / 1157 (1,6 %).
Occurrences citées rattachées à la base AutiHub
421 / 1441 (29,2 %)
Auteurices cité·es distinct·es rattaché·es : 235 / 1157 (20,3 %)
Occurrences rattachées, non identifiées comme autistes
397 / 421 (94,3 %)
Parmi les seules occurrences rattachées. Sur l’ensemble des occurrences d’auteurices cité·es : 397 / 1441 (27,6 %). Auteurices cité·es distinct·es rattaché·es, non identifié·es comme autistes : 216 / 235 (91,9 %).
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