Treatment of menopausal vasomotor symptoms and sensory issues in a 53-year-old autistic woman – a case report

This publication is included in the Autistic Autism Scholarship Project. two authors of this publication are identified as autistic in the project.

About the autistic author marker

Rynkiewicz, A., Ferensztajn‐Rochowiak, E., Moseley, R. L., Gamble-Turner, J., Hadjikhani, N., Lacroix, A., Curran, A. B., Sohl, K., & Darmochwał-Kolarz, D. (2025). Treatment of menopausal vasomotor symptoms and sensory issues in a 53-year-old autistic woman – a case report. Psychiatria i Psychologia Kliniczna, 24(4), 356-362. https://doi.org/10.15557/pipk.2024.0045

Publication date: 30 Apr 2025 Added to AutiHub: 6 Jul 2026 Type: Article Article language: English

This publication is integrated into AutiHub through:

Authors

Publication authors
9
Publication authors identified as autistic
2 / 9 (22.2%)

Abstract

Considered a taboo topic in many societies, menopause in autistic women is still under-recognised, and little research addresses its impact. Existing studies suggest that this often-difficult transition period is associated with numerous unmet health needs and a frustrating lack of knowledge and support from healthcare professionals. Menopausal vasomotor symptoms, the hallmark of menopause, can intensify and worsen sensory sensitivities in many autistic women. We present the case of a 53-year-old Caucasian autistic woman without intellectual disability or other current psychiatric comorbidities. The patient underwent gynaecologic and hormonal lab testing, and was introduced to hormone replacement therapy to ameliorate symptoms of oestradiol and progesterone deficiency. Menopausal vasomotor symptoms experienced by the patient were monitored over a period of seven months following the implementation of hormone replacement therapy and non-pharmacologic approaches. Hormone replacement therapy decreased menopausal vasomotor symptoms, but not all her initial complains. Strong sensory issues were linked to more severe menopausal vasomotor symptoms. This case highlights the need for further research and the development of the global Extension for Community Health Outcomes (ECHO) Autism® model to advance medical care offered to autistic women during menopause.

Bibliography cited by this reference

Cited references are imported from external metadata sources when they are available. The list may be partial.

Cited bibliography overview

These indicators describe the bibliography cited by this publication. An author name is counted each time it appears in one cited reference, so the same person can be counted more than once. Names not yet linked to an author already present in AutiHub are treated as unknown, not as non-autistic. Last computed: 2 Oct 2026 13:58.

Cited references
54
With a DOI
46
Without a DOI, from raw bibliography text
7
12 / 54 (22.2%) cited references include at least one author identified as autistic.
References with data to complete
7 / 54 (13.0%)
References with detected author names
47 / 54 (87.0%)
Without detected author names
7
Without a structured title
7
Without a stable identifier
7
References with raw author names still to review
7
References with external metadata lookup issues
0
These indicators apply to cited references displayed on this page, after technical duplicates have been merged. A reference without a DOI can still support author statistics when a title and author names are available.
Author names detected in the cited bibliography
278
From DOI or external metadata
278
From validated raw bibliography text
0
Raw names already validated
0
Raw names still to review
18
116 / 278 (41.7%) names are linked to an author already present in AutiHub. 162 / 278 (58.3%) names are not yet linked.
Names linked to a person identified as autistic
20 / 278 (7.2%)
Calculated across all author names detected in the cited bibliography. Among names linked to an author already present in AutiHub: 20 / 116 (17.2%). Distinct people identified as autistic: 15 / 246 (6.1%).
  1. Lindsay Till Hoyt , April M. Falconi (2015). Puberty and perimenopause: Reproductive transitions and their implications for women's health . Social Science & Medicine, 132, 103-112. Elsevier BV.
    Crossref OpenAlex OpenCitations
  2. Amber Angell , Alexis Deavenport-Saman , Larry Yin , Baiming Zou , Chen Bai , Deepthi Varma et al. (2021). Sex Differences in Co-occurring Conditions Among Autistic Children and Youth in Florida: A Retrospective Cohort Study (2012–2019) . Journal of Autism and Developmental Disorders, 51(10), 3759-3765. Springer Science and Business Media LLC.
    Crossref OpenAlex OpenCitations
  3. Micah O Mazurek , Alicia Brewer Curran , Courtney Burnette , Kristin Sohl (2019). ECHO Autism STAT: Accelerating Early Access to Autism Diagnosis . Journal of Autism and Developmental Disorders, 49(1), 127-137. Springer Science and Business Media LLC.
    Crossref OpenAlex OpenCitations
  4. Sanjeev Arora , Summers Kalishman , Karla Thornton , Denise Dion , Glen Murata , Paulina Deming et al. (2010). Expanding Access to Hepatitis C Virus Treatment—Extension for Community Healthcare Outcomes (ECHO) Project: Disruptive Innovation in Specialty Care† . Hepatology, 52(3), 1124-1133. Ovid Technologies (Wolters Kluwer Health).
    Crossref OpenAlex OpenCitations
  5. Evangelia Antoniou , Nikolaos Rigas , Eirini Orovou , Alexandros Papatrechas , Angeliki Sarella (2021). ADHD Symptoms in Females of Childhood, Adolescent, Reproductive and Menopause Period . Materia Socio Medica, 33(2), 114. ScopeMed.
    Crossref OpenAlex OpenCitations
  6. Alexa Pohl , Sarah Cassidy , Bonnie Auyeung , Simon Baron-Cohen (2014). Uncovering steroidopathy in women with autism: a latent class analysis . Molecular Autism, 5(1), 27. Springer Science and Business Media LLC.
    Crossref OpenAlex OpenCitations
  7. D. C. Deecher , K. Dorries (2007). Understanding the pathophysiology of vasomotor symptoms (hot flushes and night sweats) that occur in perimenopause, menopause, and postmenopause life stages . Archives of Women's Mental Health, 10(6), 247-257. Springer Science and Business Media LLC.
    Crossref OpenAlex OpenCitations
  8. April M. Falconi (2017). Sex-Based Differences in the Determinants of Old Age Life Expectancy: The Influence of Perimenopause . Biodemography and Social Biology, 63(1), 54-70. Informa UK Limited.
    Crossref OpenAlex OpenCitations
  9. Siobán D. Harlow , Margery Gass , Janet E. Hall , Roger Lobo , Pauline Maki , Robert W. Rebar et al. (2012). Executive summary of the Stages of Reproductive Aging Workshop + 10 . Menopause, 19(4), 387-395. Ovid Technologies (Wolters Kluwer Health).
    Crossref OpenAlex OpenCitations
  10. (n.d.). Attwood T, Garnett MS, Rynkiewicz A: Questionnaire for Autism Spectrum Conditions (Q-ASC). 2011.
    Type: Other
    Crossref
  11. Lauren Clarke , Lawrence K. Fung (2022). The impact of autism-related training programs on physician knowledge, self-efficacy, and practice behavior: A systematic review . Autism, 26(7), 1626-1640. SAGE Publications.
    Crossref OpenAlex OpenCitations
  12. Catana Brown , Nona Tollefson , Winnie Dunn , Rue Cromwell , Diane Filion (2001). The Adult Sensory Profile: Measuring Patterns of Sensory Processing . American Journal of Occupational Therapy, 55(1), 75-82. SAGE Publications.
    Crossref OpenAlex OpenCitations
  13. Michael Rutter , Ann LeCouteur , Catherine Lord (2016). Autism Diagnostic Interview-Revised . PsycTESTS Dataset, 30. American Psychological Association (APA).
    Crossref OpenAlex OpenCitations
  14. Margie E. Lachman , Salom Teshale , Stefan Agrigoroaei (2015). Midlife as a pivotal period in the life course . International Journal of Behavioral Development, 39(1), 20-31. SAGE Publications.
    Crossref OpenAlex OpenCitations
  15. Micah O Mazurek , Rachel Brown , Alicia Brewer Curran , Kristin Sohl (2017). ECHO Autism . Clinical Pediatrics, 56(3), 247-256. SAGE Publications.
    Crossref OpenAlex OpenCitations
  16. (n.d.). Cassidy S, Cogger-Ward H, Robertson AE et al.: Autism Community Priorities for Suicide Prevention: An International Society for Autism Research Policy Brief. 2021.
    Type: Other
    Crossref
  17. Arthur A. Stone , Joseph E. Schwartz , Joan E. Broderick , Angus Deaton (2010). A snapshot of the age distribution of psychological well-being in the United States . Proceedings of the National Academy of Sciences, 107(22), 9985-9990. National Academy of Sciences.
    Crossref OpenAlex OpenCitations
  18. Leann Smith DaWalt , Julie Lounds Taylor , Arezoo Movaghar , Jinkuk Hong , Bryan Kim , Murray Brilliant et al. (2021). Health profiles of adults with autism spectrum disorder: Differences between women and men . Autism Research, 14(9), 1896-1904. Wiley.
    Type: Article DOI: 10.1002/aur.2563 OpenAlex: https://openalex.org/W3173811501
    Crossref OpenAlex OpenCitations
  19. Tslil Simantov , Alexa Pohl , A. Tsompanidis , Elizabeth Weir , Michael Lombardo , Amber Ruigrok et al. (2022). Medical symptoms and conditions in autistic women . Autism, 26(2), 373-388. SAGE Publications.
    Crossref OpenAlex OpenCitations
  20. Sheila Shanmugan , James Loughead , Wen Cao , Mary D Sammel , Theodore D Satterthwaite , Kosha Ruparel et al. (2017). Impact of Tryptophan Depletion on Executive System Function during Menopause is Moderated by Childhood Adversity . Neuropsychopharmacology, 42(12), 2398-2406. Springer Science and Business Media LLC.
    Crossref OpenAlex OpenCitations
  21. Anila M. D'Mello , Isabelle R. Frosch , Cindy E. Li , Annie L. Cardinaux , John D.E. Gabrieli (2022). Exclusion of females in autism research: Empirical evidence for a “leaky” recruitment‐to‐research pipeline . Autism Research, 15(10), 1929-1940. Wiley.
    Type: Article DOI: 10.1002/aur.2795 OpenAlex: https://openalex.org/W4292601991
    Crossref OpenAlex OpenCitations
  22. Christopher Gillberg , Elisabeth Fernell , Eva Kočovská , Helen Minnis , Thomas Bourgeron , Lucy Thompson et al. (2017). The role of cholesterol metabolism and various steroid abnormalities in autism spectrum disorders: A hypothesis paper . Autism Research, 10(6), 1022-1044. Wiley.
    Type: Article DOI: 10.1002/aur.1777 OpenAlex: https://openalex.org/W2605545000
    Crossref OpenAlex OpenCitations
  23. Julien Dubreucq , Romain Coutelle , Mohamed Lajnef , Ophélia Godin , Anouck Amestoy , Paola Atzori et al. (2023). Gender differences in psychosocial function and self-reported health status in late-diagnosed autistic adults: results from the FACE-ASD national cohort . Psychological Medicine, 53(12), 5674-5684. Cambridge University Press (CUP).
    Crossref OpenAlex OpenCitations
  24. Benedikt Andreas Gasser , Johann Kurz , Bernhard Dick , Markus Georg Mohaupt (2020). Are Steroid Hormones Dysregulated in Autistic Girls? Diseases, 8(1), 6. MDPI AG.
    Crossref OpenAlex OpenCitations
  25. David Mason *Autistic author. Learn more… (2022). Healthcare barriers, what about older age? A comment on Malik-Soni et al. Pediatric Research, 91(5), 1025-1027. Springer Science and Business Media LLC.
    AutiHub · Autistic Autism Scholarship Project Crossref OpenAlex OpenCitations
  26. Annabeth P Groenman , Carolien Torenvliet , Tulsi A Radhoe , Joost A Agelink van Rentergem , Hilde M. Geurts (2022). Menstruation and menopause in autistic adults: Periods of importance? Autism, 26(6), 1563-1572. SAGE Publications.
    Crossref OpenAlex OpenCitations
  27. John H. Ward , Elizabeth Weir , Carrie T. Allison , Simon Baron-Cohen (2023). Increased rates of chronic physical health conditions across all organ systems in autistic adolescents and adults . Molecular Autism, 14(1), 35. Springer Science and Business Media LLC.
    Crossref OpenAlex OpenCitations
  28. Marianna Karavidas , Richard de Visser (2022). “It's Not Just in My Head, and It's Not Just Irrelevant”: Autistic Negotiations of Menopausal Transitions . Journal of Autism and Developmental Disorders, 52(3), 1143-1155. Springer Science and Business Media LLC.
    Crossref OpenAlex OpenCitations
  29. Vasiliki Kentrou , Milou Oostervink , Anke Scheeren , Sander Begeer (2021). Stability of co-occurring psychiatric diagnoses in autistic men and women . Research in Autism Spectrum Disorders, 82(82), 101736. Elsevier BV.
    Crossref OpenAlex OpenCitations
  30. Kathleen Riach , Margaret Rees (2022). Diversity of menopause experience in the workplace: Understanding confounding factors . Current Opinion in Endocrine and Metabolic Research, 27, 100391. Elsevier BV.
    Crossref OpenAlex OpenCitations
  31. Natasha Malik-Soni , Andrew Shaker , Helen Luck , Anne E. Mullin , Ryan E. Wiley , M. E. Suzanne Lewis et al. (2022). Tackling healthcare access barriers for individuals with autism from diagnosis to adulthood . Pediatric Research, 91(5), 1028-1035. Springer Science and Business Media LLC.
    Crossref OpenAlex OpenCitations
  32. Elizabeth Weir , Carrie T. Allison , Varun Warrier , Simon Baron-Cohen (2021). Increased prevalence of non-communicable physical health conditions among autistic adults . Autism, 25(3), 681-694. SAGE Publications.
    Crossref OpenAlex OpenCitations
  33. (n.d.). Lord C, Rutter M, DiLavore PC et al.: Autism Diagnostic Observation Schedule (ADOS-2). 2nd ed., Western Psychological Services, Torrance, CA 2012.
    Type: Other
    Crossref
  34. Ami Tint , Hilary K Brown , Simon Chen , Meng-Chuan Lai , Lesley A Tarasoff , Simone N Vigod et al. (2021). Health characteristics of reproductive-aged autistic women in Ontario: A population-based, cross-sectional study . Autism, 25(4), 1114-1124. SAGE Publications.
    Crossref OpenAlex OpenCitations
  35. Miriam I. Martini , Ralf Kuja-Halkola , Agnieszka Butwicka , Ebba Du Rietz , Brian M. D’Onofrio , Francesca Happé et al. (2022). Sex Differences in Mental Health Problems and Psychiatric Hospitalization in Autistic Young Adults . JAMA Psychiatry, 79(12), 1188. American Medical Association (AMA).
    Crossref OpenAlex OpenCitations
  36. Rae Morris , Andrea Greenblatt , Michael Saini (2023). Working Beyond Capacity: a Qualitative Review of Research on Healthcare Providers’ Experiences with Autistic Individuals . Review Journal of Autism and Developmental Disorders, 10(1), 158-168. Springer Science and Business Media LLC.
    Crossref OpenAlex OpenCitations
  37. Sarah Cassidy , Heather Cogger-Ward , Ashley Robertson , Jane Goodwin , Jacqui Rodgers (2021). Autism Community Priorities for Suicide Prevention: An International Society for Autism Research Policy Brief . ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam).
    Type: Article OpenAlex: https://openalex.org/W3201736154
    OpenAlex
  38. (n.d.). Rutter M, Bailey A, Lord C: The Social Communication Questionnaire. Western Psychological Services, Los Angeles, CA 2003a.
    Type: Other
    Crossref
  39. Kristin Sohl , Agnieszka Rynkiewicz , Valeria Nanclares-Nogués , Alicia Brewer Curran , Julie Scorah , Mandy Steiman et al. (2022). Project Extension for Community Health Outcomes (ECHO) Autism: A Successful Model to Increase Capacity in Community-Based Care . Brain Sciences, 12(3), 327. MDPI AG.
    Crossref OpenAlex OpenCitations
  40. (n.d.). Rynkiewicz A: Zaburzenia ze spektrum autyzmu u dziewcząt. Różnice międzypłciowe w obrazie klinicznym oraz współistniejąca psychopatologia. Rozprawa na stopień doktora nauk medycznych. Gdański Uniwersytet Medyczny, Gdańsk 2016.
    Type: Other
    Crossref
  41. (n.d.). Rynkiewicz A, Domarecki P, Pieniążek A et al.: [ECHO Autism Poland STAT and the GQ-ASC (Q-ASC) questionnaire. The use of autism screening assessments in the ECHO Autism Poland model. University of Rzeszow Publishing House, Rzeszów 2023.
    Type: Other
    Crossref
  42. Agnieszka Rynkiewicz , Agnieszka Rynkiewicz , Centrum Diagnozy, Terapii i Edukacji Spectrum ASC-MED, Gdańsk, Polska , Izabela Łucka , Klinika Psychiatrii Rozwojowej, Zaburzeń Psychotycznych i Wieku Podeszłego, Gdański Uniwersytet Medyczny, Gdańsk, Polska , Gabriela Grylowska et al. (2022). The future of telehealth for patients with autism spectrum disorder based on the example of Extension for Community Health Outcomes (ECHO) Autism – a global model introduced in Poland . Psychiatria i Psychologia Kliniczna, 22(2), 95-99. Medical Communications Sp. z.o.o..
    Crossref OpenAlex OpenCitations
  43. (n.d.). Women and Equalities Committee: Menopause and the workplace. 2022. https://committees.parliament.uk/work/1416/menopause-and-the-workplace/ [cited: 20 January 2025].
    Type: Other
    Crossref