Treatment of menopausal vasomotor symptoms and sensory issues in a 53-year-old autistic woman – a case report
Rynkiewicz, A., Ferensztajn‐Rochowiak, E., Moseley, R., Gamble-Turner, J., Hadjikhani, N., Lacroix, A., Curran, A. B., Sohl, K., & Darmochwał-Kolarz, D. (2025). Treatment of menopausal vasomotor symptoms and sensory issues in a 53-year-old autistic woman – a case report. Psychiatria i Psychologia Kliniczna, 24(4), 356-362. https://doi.org/10.15557/pipk.2024.0045
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Abstract
Considered a taboo topic in many societies, menopause in autistic women is still under-recognised, and little research addresses its impact. Existing studies suggest that this often-difficult transition period is associated with numerous unmet health needs and a frustrating lack of knowledge and support from healthcare professionals. Menopausal vasomotor symptoms, the hallmark of menopause, can intensify and worsen sensory sensitivities in many autistic women. We present the case of a 53-year-old Caucasian autistic woman without intellectual disability or other current psychiatric comorbidities. The patient underwent gynaecologic and hormonal lab testing, and was introduced to hormone replacement therapy to ameliorate symptoms of oestradiol and progesterone deficiency. Menopausal vasomotor symptoms experienced by the patient were monitored over a period of seven months following the implementation of hormone replacement therapy and non-pharmacologic approaches. Hormone replacement therapy decreased menopausal vasomotor symptoms, but not all her initial complains. Strong sensory issues were linked to more severe menopausal vasomotor symptoms. This case highlights the need for further research and the development of the global Extension for Community Health Outcomes (ECHO) Autism® model to advance medical care offered to autistic women during menopause.
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These indicators describe the cited bibliography imported for this publication. Cited-reference metrics use the cited-reference total as denominator. Cited-author metrics state whether they use all cited-author occurrences or only occurrences linked to authors already integrated in the AutiHub database. They use cached links between cited authors and authors integrated in the AutiHub database. Last computed: 16 Aug 2026 11:31.
-
Lindsay Till Hoyt , April M. Falconi (2015). Puberty and perimenopause: Reproductive transitions and their implications for women's health . Social Science & Medicine, 132, 103-112. Elsevier BV.Crossref OpenAlex OpenCitations
-
Amber M. Angell , Alexis Deavenport-Saman , Larry Yin , Baiming Zou , Chen Bai , Deepthi Varma et al. (2021). Sex Differences in Co-occurring Conditions Among Autistic Children and Youth in Florida: A Retrospective Cohort Study (2012–2019) . Journal of Autism and Developmental Disorders, 51(10), 3759-3765. Springer Science and Business Media LLC.Crossref OpenAlex OpenCitations
-
Micah Mazurek , Alicia Brewer Curran , Courtney Burnette , Kristin Sohl (2019). ECHO Autism STAT: Accelerating Early Access to Autism Diagnosis . Journal of Autism and Developmental Disorders, 49(1), 127-137. Springer Science and Business Media LLC.Crossref OpenAlex OpenCitations
-
Sanjeev Arora , Summers Kalishman , Karla Thornton , Denise Dion , Glen Murata , Paulina Deming et al. (2010). Expanding Access to Hepatitis C Virus Treatment—Extension for Community Healthcare Outcomes (ECHO) Project: Disruptive Innovation in Specialty Care† . Hepatology, 52(3), 1124-1133. Ovid Technologies (Wolters Kluwer Health).Crossref OpenAlex OpenCitations
-
Evangelia Antoniou , Nikolaos Rigas , Eirini Orovou , Alexandros Papatrechas , Angeliki Sarella (2021). ADHD Symptoms in Females of Childhood, Adolescent, Reproductive and Menopause Period . Materia Socio Medica, 33(2), 114. ScopeMed.Crossref OpenAlex OpenCitations
-
Alexa Pohl , Sarah Cassidy , Bonnie Auyeung , Simon Baron-Cohen (2014). Uncovering steroidopathy in women with autism: a latent class analysis . Molecular Autism, 5(1), 27. Springer Science and Business Media LLC.Crossref OpenAlex OpenCitations
-
D. C. Deecher , K. Dorries (2007). Understanding the pathophysiology of vasomotor symptoms (hot flushes and night sweats) that occur in perimenopause, menopause, and postmenopause life stages . Archives of Women's Mental Health, 10(6), 247-257. Springer Science and Business Media LLC.Crossref OpenAlex OpenCitations
-
April M. Falconi (2017). Sex-Based Differences in the Determinants of Old Age Life Expectancy: The Influence of Perimenopause . Biodemography and Social Biology, 63(1), 54-70. Informa UK Limited.Crossref OpenAlex OpenCitations
-
Siobán D. Harlow , Margery Gass , Janet E. Hall , Roger Lobo , Pauline Maki , Robert W. Rebar et al. (2012). Executive summary of the Stages of Reproductive Aging Workshop + 10 . Menopause, 19(4), 387-395. Ovid Technologies (Wolters Kluwer Health).Crossref OpenAlex OpenCitations
-
(n.d.). Attwood T, Garnett MS, Rynkiewicz A: Questionnaire for Autism Spectrum Conditions (Q-ASC). 2011.Type: OtherCrossref
-
Lauren Clarke , Lawrence K. Fung (2022). The impact of autism-related training programs on physician knowledge, self-efficacy, and practice behavior: A systematic review . Autism, 26(7), 1626-1640. SAGE Publications.Crossref OpenAlex OpenCitations
-
Catana Brown , Nona Tollefson , Winnie Dunn , Rue Cromwell , Diane Filion (2001). The Adult Sensory Profile: Measuring Patterns of Sensory Processing . American Journal of Occupational Therapy, 55(1), 75-82. SAGE Publications.Crossref OpenAlex OpenCitations
-
Michael Rutter , Ann LeCouteur , Catherine Lord (2016). Autism Diagnostic Interview-Revised . PsycTESTS Dataset, 30. American Psychological Association (APA).Crossref OpenAlex OpenCitations
-
Margie E. Lachman , Salom Teshale , Stefan Agrigoroaei (2015). Midlife as a pivotal period in the life course . International Journal of Behavioral Development, 39(1), 20-31. SAGE Publications.Crossref OpenAlex OpenCitations
-
Claire M Brown , Tony Attwood , Michelle Garnett , Mark A. Stokes (2020). Am I Autistic? Utility of the Girls Questionnaire for Autism Spectrum Condition as an Autism Assessment in Adult Women . Autism in Adulthood, 2(3), 216-226. SAGE Publications.Crossref OpenAlex OpenCitations
-
Micah Mazurek , Rachel Brown , Alicia Brewer Curran , Kristin Sohl (2017). ECHO Autism . Clinical Pediatrics, 56(3), 247-256. SAGE Publications.Crossref OpenAlex OpenCitations
-
(n.d.). Cassidy S, Cogger-Ward H, Robertson AE et al.: Autism Community Priorities for Suicide Prevention: An International Society for Autism Research Policy Brief. 2021.Type: OtherCrossref
-
Arthur A. Stone , Joseph E. Schwartz , Joan E. Broderick , Angus Deaton (2010). A snapshot of the age distribution of psychological well-being in the United States . Proceedings of the National Academy of Sciences, 107(22), 9985-9990. National Academy of Sciences.Crossref OpenAlex OpenCitations
-
Leann Smith DaWalt , Julie Lounds Taylor , Arezoo Movaghar , Jinkuk Hong , Bryan Kim , Murray Brilliant et al. (2021). Health profiles of adults with autism spectrum disorder: Differences between women and men . Autism Research, 14(9), 1896-1904. Wiley.Crossref OpenAlex OpenCitations
-
Robyn Steward *Autistic author. Learn more… , Laura Crane , Eilish Mairi Roy , Anna Remington , Elizabeth Pellicano (2018). “Life is Much More Difficult to Manage During Periods”: Autistic Experiences of Menstruation . Journal of Autism and Developmental Disorders, 48(12), 4287-4292. Springer Science and Business Media LLC.
-
Tslil Simantov , Alexa Pohl , Alexandros Tsompanidis , Elizabeth M Weir , Michael Lombardo , Amber Ruigrok et al. (2022). Medical symptoms and conditions in autistic women . Autism, 26(2), 373-388. SAGE Publications.Crossref OpenAlex OpenCitations
-
Sheila Shanmugan , James Loughead , Wen Cao , Mary D Sammel , Theodore D Satterthwaite , Kosha Ruparel et al. (2017). Impact of Tryptophan Depletion on Executive System Function during Menopause is Moderated by Childhood Adversity . Neuropsychopharmacology, 42(12), 2398-2406. Springer Science and Business Media LLC.Crossref OpenAlex OpenCitations
-
Anila M. D'Mello , Isabelle R. Frosch , Cindy E. Li , Annie L. Cardinaux , John D.E. Gabrieli (2022). Exclusion of females in autism research: Empirical evidence for a “leaky” recruitment‐to‐research pipeline . Autism Research, 15(10), 1929-1940. Wiley.Crossref OpenAlex OpenCitations
-
Christopher Gillberg , Elisabeth Fernell , Eva Kočovská , H. Minnis , Thomas Bourgeron , Lucy Thompson et al. (2017). The role of cholesterol metabolism and various steroid abnormalities in autism spectrum disorders: A hypothesis paper . Autism Research, 10(6), 1022-1044. Wiley.Crossref OpenAlex OpenCitations
-
Mary Doherty *Autistic author. Learn more… , Stuart Neilson , Jane O’Sullivan , Laura Carravallah *Autistic author. Learn more… , Mona Johnson *Autistic author. Learn more… , Walter Cullen et al. (2022). Barriers to healthcare and self-reported adverse outcomes for autistic adults: a cross-sectional study . BMJ Open, 12(2), e056904. BMJ.
-
Georgina Warner , Jeremy R. Parr , James Cusack *Autistic author. Learn more… (2019). Workshop Report: Establishing Priority Research Areas to Improve the Physical Health and Well-Being of Autistic Adults and Older People . Autism in Adulthood, 1(1), 20-26. SAGE Publications.
-
Sarah Mae Simcoe , Charlotte Brownlow , Michelle Sarah Garnett , Agnieszka Rynkiewicz , Tony Attwood (2018). Profiling Autism Symptomatology: An Exploration of the Q-ASC Parental Report Scale in Capturing Sex Differences in Autism . Journal of Autism and Developmental Disorders, 48(2), 389-403. Springer Science and Business Media LLC.Crossref OpenAlex OpenCitations
-
Julien Dubreucq , Romain Coutelle , Mohamed Lajnef , Ophélia Godin , Anouck Amestoy , Paola Atzori et al. (2023). Gender differences in psychosocial function and self-reported health status in late-diagnosed autistic adults: results from the FACE-ASD national cohort . Psychological Medicine, 53(12), 5674-5684. Cambridge University Press (CUP).Crossref OpenAlex OpenCitations
-
David Mason , Barry Ingham , Anna Urbanowicz , Cos Michael , Heather Birtles , Marc Woodbury‐Smith et al. (2019). A Systematic Review of What Barriers and Facilitators Prevent and Enable Physical Healthcare Services Access for Autistic Adults . Journal of Autism and Developmental Disorders, 49(8), 3387-3400. Springer Science and Business Media LLC.
-
Benedikt Andreas Gasser , Johann Kurz , Bernhard Dick , Markus Georg Mohaupt (2020). Are Steroid Hormones Dysregulated in Autistic Girls? Diseases, 8(1), 6. MDPI AG.Crossref OpenAlex OpenCitations
-
David Mason (2022). Healthcare barriers, what about older age? A comment on Malik-Soni et al. Pediatric Research, 91(5), 1025-1027. Springer Science and Business Media LLC.Crossref OpenAlex OpenCitations
-
Annabeth P Groenman , Carolien Torenvliet , Tulsi A Radhoe , Joost A Agelink van Rentergem , Hilde M. Geurts (2022). Menstruation and menopause in autistic adults: Periods of importance? Autism, 26(6), 1563-1572. SAGE Publications.Crossref OpenAlex OpenCitations
-
John H. Ward , Elizabeth M Weir , Carrie Allison , Simon Baron-Cohen (2023). Increased rates of chronic physical health conditions across all organ systems in autistic adolescents and adults . Molecular Autism, 14(1), 35-35. Springer Science and Business Media LLC.Crossref OpenAlex OpenCitations
-
Rachel Moseley *Autistic author. Learn more… , Tanya Druce , Julie Gamble-Turner (2020). ‘When my autism broke’: A qualitative study spotlighting autistic voices on menopause . Autism, 24(6), 1423-1437. SAGE Publications.
-
Marianna Karavidas , Richard de Visser (2022). “It's Not Just in My Head, and It's Not Just Irrelevant”: Autistic Negotiations of Menopausal Transitions . Journal of Autism and Developmental Disorders, 52(3), 1143-1155. Springer Science and Business Media LLC.Crossref OpenAlex OpenCitations
-
Vasiliki Kentrou , Milou Oostervink , Anke Scheeren , Sander Begeer (2021). Stability of co-occurring psychiatric diagnoses in autistic men and women . Research in Autism Spectrum Disorders, 82, 101736. Elsevier BV.Crossref OpenAlex OpenCitations
-
Kathleen Riach , Margaret Rees (2022). Diversity of menopause experience in the workplace: Understanding confounding factors . Current Opinion in Endocrine and Metabolic Research, 27, 100391. Elsevier BV.Crossref OpenAlex OpenCitations
-
Christina Nicolaidis , Gavin Schnider , Junghee Lee , Dora M Raymaker *Autistic author. Learn more… , Steven K. Kapp *Autistic author. Learn more… , Lisa A. Croen et al. (2021). Development and psychometric testing of the AASPIRE Adult Autism Healthcare Provider Self-Efficacy Scale . Autism, 25(3), 767-773. SAGE Publications.
-
Natasha Malik-Soni , Andrew Shaker , Helen Luck , Anne E. Mullin , Ryan E. Wiley , M. E. Suzanne Lewis et al. (2022). Tackling healthcare access barriers for individuals with autism from diagnosis to adulthood . Pediatric Research, 91(5), 1028-1035. Springer Science and Business Media LLC.Crossref OpenAlex OpenCitations
-
Elizabeth M Weir , Carrie Allison , Varun Warrier , Simon Baron-Cohen (2021). Increased prevalence of non-communicable physical health conditions among autistic adults . Autism, 25(3), 681-694. SAGE Publications.Crossref OpenAlex OpenCitations
-
(n.d.). Lord C, Rutter M, DiLavore PC et al.: Autism Diagnostic Observation Schedule (ADOS-2). 2nd ed., Western Psychological Services, Torrance, CA 2012.Type: OtherCrossref
-
Rachel Moseley *Autistic author. Learn more… , Tanya Druce , Julie Gamble-Turner (2021). Autism research is ‘all about the blokes and the kids’: Autistic women breaking the silence on menopause . British Journal of Health Psychology, 26(3), 709-726. Wiley.
-
Ami Tint , Hilary K Brown , Simon Chen , Meng-Chuan Lai , Lesley A Tarasoff , Simone N Vigod et al. (2021). Health characteristics of reproductive-aged autistic women in Ontario: A population-based, cross-sectional study . Autism, 25(4), 1114-1124. SAGE Publications.Crossref OpenAlex OpenCitations
-
Miriam I. Martini , Ralf Kuja-Halkola , Agnieszka Butwicka , Ebba Du Rietz , Brian M. D’Onofrio , Francesca Happé et al. (2022). Sex Differences in Mental Health Problems and Psychiatric Hospitalization in Autistic Young Adults . JAMA Psychiatry, 79(12), 1188. American Medical Association (AMA).Crossref OpenAlex OpenCitations
-
David Mason , Gavin R. Stewart , Simone Josephine Capp , Francesca Happé (2022). Older Age Autism Research: A Rapidly Growing Field, but Still a Long Way to Go . Autism in Adulthood, 4(2), 164-172. SAGE Publications.Crossref OpenAlex OpenCitations
-
Rae Morris , Andrea Greenblatt , Michael Saini (2023). Working Beyond Capacity: a Qualitative Review of Research on Healthcare Providers’ Experiences with Autistic Individuals . Review Journal of Autism and Developmental Disorders, 10(1), 158-168. Springer Science and Business Media LLC.Crossref OpenAlex OpenCitations
-
Sarah Cassidy , Heather Cogger-Ward , Ashley Robertson , Jane Goodwin , Jacqui Rodgers (2021). Autism Community Priorities for Suicide Prevention: An International Society for Autism Research Policy Brief . ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam).Type: Article OpenAlex: https://openalex.org/W3201736154OpenAlex
-
(n.d.). Rutter M, Bailey A, Lord C: The Social Communication Questionnaire. Western Psychological Services, Los Angeles, CA 2003a.Type: OtherCrossref
-
Agnieszka Rynkiewicz , Shuting Zheng , Adeline Lacroix *Autistic author. Learn more… (2024). Special considerations for assessing and caring for autism in girls and women . Current Opinion in Psychiatry, 37(2), 71-77. Ovid Technologies (Wolters Kluwer Health).
-
Kristin Sohl , Agnieszka Rynkiewicz , Valeria Nanclares-Nogués , Alicia Brewer Curran , Julie Scorah , Mandy Steiman et al. (2022). Project Extension for Community Health Outcomes (ECHO) Autism: A Successful Model to Increase Capacity in Community-Based Care . Brain Sciences, 12(3), 327. MDPI AG.Crossref OpenAlex OpenCitations
-
(n.d.). Rynkiewicz A: Zaburzenia ze spektrum autyzmu u dziewcząt. Różnice międzypłciowe w obrazie klinicznym oraz współistniejąca psychopatologia. Rozprawa na stopień doktora nauk medycznych. Gdański Uniwersytet Medyczny, Gdańsk 2016.Type: OtherCrossref
-
(n.d.). Rynkiewicz A, Domarecki P, Pieniążek A et al.: [ECHO Autism Poland STAT and the GQ-ASC (Q-ASC) questionnaire. The use of autism screening assessments in the ECHO Autism Poland model. University of Rzeszow Publishing House, Rzeszów 2023.Type: OtherCrossref
-
Agnieszka Rynkiewicz , Agnieszka Rynkiewicz , Centrum Diagnozy, Terapii i Edukacji Spectrum ASC-MED, Gdańsk, Polska , Izabela Łucka , Klinika Psychiatrii Rozwojowej, Zaburzeń Psychotycznych i Wieku Podeszłego, Gdański Uniwersytet Medyczny, Gdańsk, Polska , Gabriela Grylowska et al. (2022). The future of telehealth for patients with autism spectrum disorder based on the example of Extension for Community Health Outcomes (ECHO) Autism – a global model introduced in Poland . Psychiatria i Psychologia Kliniczna, 22(2), 95-99. Medical Communications Sp. z.o.o..Crossref OpenAlex OpenCitations
-
(n.d.). Women and Equalities Committee: Menopause and the workplace. 2022. https://committees.parliament.uk/work/1416/menopause-and-the-workplace/ [cited: 20 January 2025].Type: OtherCrossref