Autism spectrum disorder

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Lord, C., Brugha, T., Charman, T., Cusack, J., Dumas, G., Frazier, T., Jones, E. J., Jones, R. M., Pickles, A., State, M. W., Taylor, J. L., & Veenstra‐VanderWeele, J. (2020). Autism spectrum disorder. Nature Reviews Disease Primers, 6(1), 5-5. https://doi.org/10.1038/s41572-019-0138-4

Publication date: 16 Jan 2020 Added to AutiHub: 5 Jul 2026 Type: Article Article language: English
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Authors

Publication authors
12
Publication authors identified as autistic
1 / 12 (8.3%)
  1. Catherine Lord
  2. Traolach Brugha
  3. Tony Charman
  4. James Cusack *
  1. Guillaume Dumas
  2. Thomas Frazier
  3. Emily J.H. Jones
  4. Rebecca M. Jones
  1. Andrew Pickles
  2. Matthew W. State
  3. Julie Lounds Taylor
  4. Jeremy Veenstra‐VanderWeele

Abstract

Autism spectrum disorder is a construct used to describe individuals with a specific combination of impairments in social communication and repetitive behaviours, highly restricted interests and/or sensory behaviours beginning early in life. The worldwide prevalence of autism is just under 1%, but estimates are higher in high-income countries. Although gross brain pathology is not characteristic of autism, subtle anatomical and functional differences have been observed in post-mortem, neuroimaging and electrophysiological studies. Initially, it was hoped that accurate measurement of behavioural phenotypes would lead to specific genetic subtypes, but genetic findings have mainly applied to heterogeneous groups that are not specific to autism. Psychosocial interventions in children can improve specific behaviours, such as joint attention, language and social engagement, that may affect further development and could reduce symptom severity. However, further research is necessary to identify the long-term needs of people with autism, and treatments and the mechanisms behind them that could result in improved independence and quality of life over time. Families are often the major source of support for people with autism throughout much of life and need to be considered, along with the perspectives of autistic individuals, in both research and practice.

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These indicators describe the cited bibliography imported for this publication. Cited-reference metrics use the cited-reference total as denominator. Cited-author metrics state whether they use all cited-author occurrences or only occurrences linked to authors already integrated in the AutiHub database. They use cached links between cited authors and authors integrated in the AutiHub database. Last computed: 16 Aug 2026 11:30.

Cited references
463
Total cited references integrated for this publication.
Cited references with an identified autistic author
3 / 463 (0.6%)
Cited author occurrences identified as autistic
5 / 6127 (0.1%)
Among occurrences linked to AutiHub author records: 5 / 591 (0.8%). Distinct cited authors identified as autistic: 5 / 4480 (0.1%).
Cited author occurrences linked to AutiHub author records
591 / 6127 (9.6%)
Distinct linked cited authors: 184 / 4480 (4.1%)
Linked cited-author occurrences not identified as autistic
586 / 591 (99.2%)
Among linked cited-author occurrences only. Across all cited-author occurrences: 586 / 6127 (9.6%). Distinct linked cited authors not identified as autistic: 179 / 184 (97.3%).
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