Les réponses de prédiction et de négativité de discordance reflètent des altérations du traitement sémantique de l'action chez des adultes présentant des troubles du spectre de l'autisme
Titre original en anglais : Prediction and Mismatch Negativity Responses Reflect Impairments in Action Semantic Processing in Adults With Autism Spectrum Disorders
Grisoni, L., Moseley, R., Motlagh, S., Kandia, D., Sener, N., Pulvermüller, F., Roepke, S., & Mohr, B. (2019). Prediction and Mismatch Negativity Responses Reflect Impairments in Action Semantic Processing in Adults With Autism Spectrum Disorders. Frontiers in Human Neuroscience, 13, 395-395. https://doi.org/10.3389/fnhum.2019.00395
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Résumé
Les mécanismes neurophysiologiques sous-tendant les difficultés motrices et langagières dans les troubles du spectre de l'autisme (TSA) restent encore largement incertains. Le présent travail étudie des indicateurs biologiques du traitement des sons, de la compréhension sémantique (de l'action) et du codage prédictif, ainsi que leur corrélation avec les symptômes cliniques des TSA. Vingt-deux adultes présentant un TSA de haut niveau de fonctionnement et 25 participants au développement typique (TD) ont participé à une tâche auditive passive d'écoute de négativité de discordance (MMN), tandis qu'une électroencéphalographie (EEG) à haute densité était enregistrée. Des mots d'action et de non-action ont été présentés dans le contexte de sons, qui étaient soit sémantiquement congruents au regard de la partie du corps à laquelle ils se rapportent, soit sémantiquement incongruents ou non apparentés. L'activité anticipatoire avant le début du son, le potentiel de prédiction (PP), était significativement réduite dans le groupe TSA spécifiquement pour les sons d'action, mais non pour les sons de non-action. Les réponses précoces de type MMN aux mots (latence : 120 ms) étaient modulées différemment selon les groupes : les témoins présentaient des amplitudes plus importantes pour les mots dans des contextes sonores d'action que dans des contextes de non-action, tandis que les participants TSA ne manifestaient des réponses précoces de type MMN accrues que dans un contexte de son pur, sans autre modulation dépendante du contexte sonore d'action. Les réponses tardives de type MMN, environ 560 ms après le début du stimulus, ont révélé un amorçage sémantique de l'action congruent avec la partie du corps pour les mots chez les participants témoins, mais non dans le groupe TSA. Il est important de noter que les indices neurophysiologiques d'amorçage sémantique chez les participants TSA étaient corrélés à l'ampleur des traits autistiques, telle que révélée par l'Autism Spectrum Quotient (AQ). Les données suggèrent que les adultes de haut niveau de fonctionnement présentant un TSA montrent un déficit spécifique du traitement sémantique et du codage prédictif des sons et des mots liés à l'action, qui est absent pour les sons neutres, de non-action.
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Ces indicateurs décrivent la bibliographie citée importée pour cette publication. Les métriques de références citées utilisent le total des références citées comme dénominateur. Les métriques d’auteurices cité·es indiquent si elles utilisent toutes les occurrences d’auteurices cité·es ou seulement les occurrences rattachées à des auteurices déjà intégré·es à la base de données AutiHub. Ils utilisent les rattachements mis en cache entre les auteurices cité·es et les auteurices intégré·es à la base de données AutiHub. Dernier calcul : 16/08/2026 11:31.
-
Laura Sparaci , Silvia Stefanini , Lidia D'Elia , Stefano Vicari , Giacomo Rizzolatti (2014). What and Why Understanding in Autism Spectrum Disorders and W illiams Syndrome: Similarities and Differences . Autism Research, 7(4), 421-432. Wiley.Crossref OpenAlex OpenCitations
-
González Moreno, Andrés Santiago (2013). Diagnostic and Statistical Manual of Mental Disorders . American Psychiatric Association.Crossref OpenAlex OpenCitations
-
Elizabeth Pellicano , David Burr (2012). When the world becomes ‘too real’: a Bayesian explanation of autistic perception . Trends in Cognitive Sciences, 16(10), 504-510. Elsevier BV.Crossref OpenAlex OpenCitations
-
Martin H. Fischer , Rolf A. Zwaan (2008). Embodied Language: A Review of the Role of the Motor System in Language Comprehension . Quarterly Journal of Experimental Psychology, 61(6), 825-850. SAGE Publications.Crossref OpenAlex OpenCitations
-
Simon Baron-Cohen (2009). Autism: The Empathizing–Systemizing (E‐S) Theory . Annals of the New York Academy of Sciences, 1156(1), 68-80. Wiley.Crossref OpenAlex OpenCitations
-
Rachel Moseley *Auteur·ice autiste. En savoir plus… , Bettina Mohr , Michael Lombardo , Simon Baron-Cohen , Olaf Hauk , Friedemann Pulvermüller (2013). Brain and behavioral correlates of action semantic deficits in autism . Frontiers in Human Neuroscience, 7, 725-725. Frontiers Media SA.
-
Amanda Ludlow , Bettina Mohr , Antony Whitmore , Max Garagnani , Friedemann Pulvermüller , Roberto Gutierrez (2014). Auditory processing and sensory behaviours in children with autism spectrum disorders as revealed by mismatch negativity . Brain and Cognition, 86, 55-63. Elsevier BV.Crossref OpenAlex OpenCitations
-
Simon Baron-Cohen , Sally Wheelwright , Richard Skinner , Joanne Martin , Emma Clubley (2001). The Autism-Spectrum Quotient (AQ): Evidence from Asperger Syndrome/High-Functioning Autism, Males and Females, Scientists and Mathematicians . Journal of Autism and Developmental Disorders, 31(1), 5-17. Springer Science and Business Media LLC.Crossref OpenAlex
-
Rachel Moseley *Auteur·ice autiste. En savoir plus… , Friedemann Pulvermüller , Bettina Mohr , Michael Lombardo , Simon Baron-Cohen , Yury Shtyrov (2014). Brain Routes for Reading in Adults with and without Autism: EMEG Evidence . Journal of Autism and Developmental Disorders, 44(1), 137-153. Springer Science and Business Media LLC.
-
R. Näätänen , P. Paavilainen , T. Rinne , K. Alho (2007). The mismatch negativity (MMN) in basic research of central auditory processing: A review . Clinical Neurophysiology, 118(12), 2544-2590. Elsevier BV.Crossref OpenAlex OpenCitations
-
Lawrence W. Barsalou (2008). Grounded Cognition . Annual Review of Psychology, 59(1), 617-645. Annual Reviews.Type: Article DOI: 10.1146/annurev.psych.59.103006.093639 OpenAlex: https://openalex.org/W4212844288Crossref OpenAlex OpenCitations
-
Rachel Moseley *Auteur·ice autiste. En savoir plus… , Yury Shtyrov , Bettina Mohr , Michael Lombardo , Simon Baron-Cohen , Friedemann Pulvermüller (2015). Lost for emotion words: What motor and limbic brain activity reveals about autism and semantic theory . NeuroImage, 104, 413-422. Elsevier BV.
-
Kimberly A. Fournier , Chris J. Hass , Sagar K. Naik , Neha Lodha , James H. Cauraugh (2010). Motor Coordination in Autism Spectrum Disorders: A Synthesis and Meta-Analysis . Journal of Autism and Developmental Disorders, 40(10), 1227-1240. Springer Science and Business Media LLC.Crossref OpenAlex OpenCitations
-
Jacob Cohen (1973). Eta-Squared and Partial Eta-Squared in Fixed Factor Anova Designs . Educational and Psychological Measurement, 33(1), 107-112. SAGE Publications.Crossref OpenAlex OpenCitations
-
Stewart H. Mostofsky , Joshua B. Ewen (2011). Altered Connectivity and Action Model Formation in Autism Is Autism . The Neuroscientist, 17(4), 437-448. SAGE Publications.Crossref OpenAlex OpenCitations
-
Eira Jansson-Verkasalo , Rita Ceponiene , Marko Kielinen , Kalervo Suominen , Ville Jäntti , Sirkka-Liisa Linna et al. (2003). Deficient auditory processing in children with Asperger Syndrome, as indexed by event-related potentials . Neuroscience Letters, 338(3), 197-200. Elsevier BV.Crossref OpenAlex OpenCitations
-
Cohen (1988). Statistical Power Analysis for the Behavioral Sciences. Statistical Power Analysis for the Behavioral Sciences.Type: AutreCrossref
-
Friedemann Pulvermüller , Luciano Fadiga (2010). Active perception: sensorimotor circuits as a cortical basis for language . Nature Reviews Neuroscience, 11(5), 351-360. Springer Science and Business Media LLC.Crossref OpenAlex OpenCitations
-
L�der Deecke , Peter Scheid , HansH. Kornhuber (1969). Distribution of readiness potential, pre-motion positivity, and motor potential of the human cerebral cortex preceding voluntary finger movements . Experimental Brain Research, 7(2), 158. Springer Science and Business Media LLC.Crossref OpenAlex OpenCitations
-
Friedemann Pulvermüller , Yury Shtyrov , Risto J. Ilmoniemi , William D. Marslen-Wilson (2006). Tracking speech comprehension in space and time . NeuroImage, 31(3), 1297-1305. Elsevier BV.Crossref OpenAlex OpenCitations
-
R. Näätänen , T. Kujala , C. Escera , T. Baldeweg , K. Kreegipuu , S. Carlson et al. (2012). The mismatch negativity (MMN) – A unique window to disturbed central auditory processing in ageing and different clinical conditions . Clinical Neurophysiology, 123(3), 424-458. Elsevier BV.Crossref OpenAlex OpenCitations
-
Giacomo Rizzolatti , Corrado Sinigaglia (2010). The functional role of the parieto-frontal mirror circuit: interpretations and misinterpretations . Nature Reviews Neuroscience, 11(4), 264-274. Springer Science and Business Media LLC.Crossref OpenAlex OpenCitations
-
Abigail Thompson , Declan Murphy , Flavio Dell’Acqua , Christine Ecker , Gráinne McAlonan , Henrietta Howells et al. (2017). Impaired Communication Between the Motor and Somatosensory Homunculus Is Associated With Poor Manual Dexterity in Autism Spectrum Disorder . Biological Psychiatry, 81(3), 211-219. Elsevier BV.Crossref OpenAlex OpenCitations
-
Marie Gomot , Marie‐Hélène Giard , Jean‐Louis Adrien , Catherine Barthelemy , Nicole Bruneau (2002). Hypersensitivity to acoustic change in children with autism: Electrophysiological evidence of left frontal cortex dysfunctioning . Psychophysiology, 39(5), 577-584. Wiley.Crossref OpenCitations
-
T. Kujala , T. Lepistö , R. Näätänen (2013). The neural basis of aberrant speech and audition in autism spectrum disorders . Neuroscience & Biobehavioral Reviews, 37(4), 697-704. Elsevier BV.Crossref OpenAlex OpenCitations
-
James M Kilner , Claudia Vargas , Sylvie Duval , Sarah-Jayne Blakemore , Angela Sirigu (2004). Motor activation prior to observation of a predicted movement . Nature Neuroscience, 7(12), 1299-1301. Springer Science and Business Media LLC.Crossref OpenAlex OpenCitations
-
Samuel W. Greenhouse , Seymour Geisser (1959). On Methods in the Analysis of Profile Data . Psychometrika, 24(2), 95-112. Cambridge University Press (CUP).Crossref OpenAlex OpenCitations
-
Teija Kujala , Mari Tervaniemi , Erich Schröger (2007). The mismatch negativity in cognitive and clinical neuroscience: Theoretical and methodological considerations . Biological Psychology, 74(1), 1-19. Elsevier BV.Crossref OpenAlex OpenCitations
-
Tuulia Lepistö , Teija Kujala , Raija Vanhala , Paavo Alku , Minna Huotilainen , Risto Näätänen (2005). The discrimination of and orienting to speech and non-speech sounds in children with autism . Brain Research, 1066(1-2), 147-157. Elsevier BV.Crossref OpenAlex OpenCitations
-
Luigi Grisoni , Felix R. Dreyer , Friedemann Pulvermüller (2016). Somatotopic Semantic Priming and Prediction in the Motor System . Cerebral Cortex, 26(5), 2353-2366. Oxford University Press (OUP).Crossref OpenAlex OpenCitations
-
Giacomo Rizzolatti , Maddalena Fabbri-Destro (2010). Mirror neurons: from discovery to autism . Experimental Brain Research, 200(3-4), 223-237. Springer Science and Business Media LLC.Crossref OpenAlex OpenCitations
-
Friedemann Pulvermüller , Teija Kujala , Yury Shtyrov , Jaana Simola , Hannu Tiitinen , Paavo Alku et al. (2001). Memory Traces for Words as Revealed by the Mismatch Negativity . NeuroImage, 14(3), 607-616. Elsevier BV.Crossref OpenAlex OpenCitations
-
Luigi Grisoni , Tally McCormick Miller , Friedemann Pulvermüller (2017). Neural Correlates of Semantic Prediction and Resolution in Sentence Processing . The Journal of Neuroscience, 37(18), 4848-4858. Society for Neuroscience.Crossref OpenAlex OpenCitations
-
Luigi Grisoni , Bettina Mohr , Friedemann Pulvermüller (2019). Prediction mechanisms in motor and auditory areas and their role in sound perception and language understanding . NeuroImage, 199, 206-216. Elsevier BV.Crossref OpenAlex OpenCitations
-
Lucy J MacGregor , Friedemann Pulvermüller , Maarten van Casteren , Yury Shtyrov (2012). Ultra-rapid access to words in the brain . Nature Communications, 3(1), 711. Springer Science and Business Media LLC.Crossref OpenAlex OpenCitations
-
Horn (1983). Leistungsprüfsystem: L-P-S. Leistungsprüfsystem: L-P-S..Type: AutreCrossref
-
T. Lepistö , M. Kajander , R. Vanhala , P. Alku , M. Huotilainen , R. Näätänen et al. (2008). The perception of invariant speech features in children with autism . Biological Psychology, 77(1), 25-31. Elsevier BV.Crossref OpenAlex OpenCitations
-
Marco Iacoboni (2009). Imitation, Empathy, and Mirror Neurons . Annual Review of Psychology, 60(1), 653-670. Annual Reviews.Type: Article DOI: 10.1146/annurev.psych.60.110707.163604 OpenAlex: https://openalex.org/W2101837595Crossref OpenAlex OpenCitations
-
James M. Kilner , Karl J. Friston , Chris D. Frith (2007). Predictive coding: an account of the mirror neuron system . Cognitive Processing, 8(3), 159-166. Springer Science and Business Media LLC.Crossref OpenAlex OpenCitations
-
Erich Schröger (1998). Measurement and interpretation of the mismatch negativity . Behavior Research Methods, Instruments, & Computers, 30(1), 131-145. Springer Science and Business Media LLC.Crossref OpenAlex OpenCitations
-
Patricia K. Kuhl , Sharon Coffey‐Corina , Denise Padden , Géraldine Dawson (2005). Links between social and linguistic processing of speech in preschool children with autism: behavioral and electrophysiological measures . Developmental Science, 8(1), 1. Wiley.Crossref OpenAlex OpenCitations
-
Megan MacDonald , Catherine Lord , Dale A. Ulrich (2014). Motor Skills and Calibrated Autism Severity in Young Children With Autism Spectrum Disorder . Adapted Physical Activity Quarterly, 31(2), 95-105. Human Kinetics.Crossref OpenAlex OpenCitations
-
Jonathan Sussman-Fort , Elyse Sussman (2014). The effect of stimulus context on the buildup to stream segregation . Frontiers in Neuroscience, 8, 93. Frontiers Media SA.Crossref OpenAlex OpenCitations
-
Justin H. G. Williams , Jackie M. Casey , Lieke Braadbaart , Peter R. Culmer , Mark Mon-Williams (2014). Kinematic Measures of Imitation Fidelity in Primary School Children . Journal of Cognition and Development, 15(2), 345-362. Informa UK Limited.OpenCitations
-
Pawan Sinha , Margaret M. Kjelgaard , Tapan K. Gandhi , Kleovoulos Tsourides , Annie L. Cardinaux , Dimitrios Pantazis et al. (2014). Autism as a disorder of prediction . Proceedings of the National Academy of Sciences, 111(42), 15220-15225. National Academy of Sciences.Crossref OpenAlex OpenCitations
-
Risto Näätänen , Elyse S. Sussman , Dean Salisbury , Valerie L. Shafer (2014). Mismatch Negativity (MMN) as an Index of Cognitive Dysfunction . Brain Topography, 27(4), 451-466. Springer Science and Business Media LLC.Crossref OpenAlex OpenCitations
-
Friedemann Pulvermüller , Yury Shtyrov (2006). Language outside the focus of attention: The mismatch negativity as a tool for studying higher cognitive processes . Progress in Neurobiology, 79(1), 49-71. Elsevier BV.Crossref OpenAlex OpenCitations
-
Friedemann Pulvermüller , Rachel Moseley *Auteur·ice autiste. En savoir plus… , Natalia Egorova , Zubaida Shebani , Véronique Boulenger (2014). Motor cognition–motor semantics: Action perception theory of cognition and communication . Neuropsychologia, 55, 71-84. Elsevier BV.Type: Article DOI: 10.1016/j.neuropsychologia.2013.12.002 OpenAlex: https://openalex.org/W2096203066Crossref OpenAlex OpenCitations
-
Sander Van de Cruys , Kris Evers , Ruth Van der Hallen , Lien Van Eylen , Bart Boets , Lee de-Wit et al. (2014). Precise minds in uncertain worlds: Predictive coding in autism. Psychological Review, 121(4), 649-675. American Psychological Association (APA).Crossref OpenAlex OpenCitations
-
Rachel Moseley *Auteur·ice autiste. En savoir plus… , Friedemann Pulvermüller (2018). What can autism teach us about the role of sensorimotor systems in higher cognition? New clues from studies on language, action semantics, and abstract emotional concept processing . Cortex, 100, 149-190. Elsevier BV.
-
Yury Shtyrov , Olaf Hauk , Friedemann Pulvermüller (2004). Distributed neuronal networks for encoding category‐specific semantic information: the mismatch negativity to action words . European Journal of Neuroscience, 19(4), 1083-1092. Wiley.Crossref OpenAlex OpenCitations
-
Lilly Schmidt , Jennifer Kirchner , Sandra Strunz , Julia Broźus , Kathrin Ritter , Stefan Roepke et al. (2015). Psychosocial Functioning and Life Satisfaction in Adults With Autism Spectrum Disorder Without Intellectual Impairment . Journal of Clinical Psychology, 71(12), 1259-1268. Wiley.Crossref OpenAlex OpenCitations
-
Yury Shtyrov , Galina Goryainova , Sergei Tugin , Alexey Ossadtchi , Anna Shestakova (2013). Automatic processing of unattended lexical information in visual oddball presentation: neurophysiological evidence . Frontiers in Human Neuroscience, 7, 421. Frontiers Media SA.Crossref OpenAlex OpenCitations
-
R.C. Oldfield (1971). The assessment and analysis of handedness: The Edinburgh inventory . Neuropsychologia, 9(1), 97-113. Elsevier BV.Crossref OpenAlex
-
Friedemann Pulvermüller (2018). Neural reuse of action perception circuits for language, concepts and communication . Progress in Neurobiology, 160, 1-44. Elsevier BV.Crossref OpenAlex OpenCitations
-
Friedemann Pulvermüller , Yury Shtyrov , Olaf Hauk (2009). Understanding in an instant: Neurophysiological evidence for mechanistic language circuits in the brain . Brain and Language, 110(2), 81-94. Elsevier BV.Crossref OpenAlex OpenCitations
-
Isabelle Rapin , Michelle Dunn (2003). Update on the language disorders of individuals on the autistic spectrum . Brain and Development, 25(3), 166-172. Elsevier BV.Crossref OpenAlex OpenCitations
-
Yury Shtyrov , Anna Butorina , Anastasia Nikolaeva , Tatiana Stroganova (2014). Automatic ultrarapid activation and inhibition of cortical motor systems in spoken word comprehension . Proceedings of the National Academy of Sciences, 111(18), E1918. National Academy of Sciences.Crossref OpenAlex OpenCitations
-
Marie Gomot , Marie‐Hélène Giard , Jean‐Louis Adrien , Catherine Barthelemy , Nicole Bruneau (2002). Hypersensitivity to acoustic change in children with autism: Electrophysiological evidence of left frontal cortex dysfunctioning . Psychophysiology, 39(5), 577-584. Wiley.OpenAlex
-
Keith Muller , Jacob Cohen (1989). Statistical Power Analysis for the Behavioral Sciences . Technometrics, 31(4), 499-500. Informa UK Limited.OpenAlex