Trajectories of adaptive functioning from early childhood to adolescence in autism: Identifying turning points and key correlates of chronogeneity

This publication is included in the Autistic Autism Scholarship Project. one author of this publication is identified as autistic in the project.

About the autistic author marker

Chen, Y., Duku, E., Szatmari, P., Salt, M., Smith, I., Richard, A., Zwaigenbaum, L., Vaillancourt, T., Zaidman‐Zait, A., Bennett, T., Elsabbagh, M., Kerns, C., & Georgiades, S. (2023). Trajectories of adaptive functioning from early childhood to adolescence in autism: Identifying turning points and key correlates of chronogeneity. JCPP Advances, 4(2), e12212-e12212. https://doi.org/10.1002/jcv2.12212

Publication date: 14 Dec 2023 Added to AutiHub: 29 Sep 2026 Type: Article Article language: English

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Authors

Publication authors
13
Publication authors identified as autistic
1 / 13 (7.7%)

Abstract

Abstract Background Previous research has demonstrated heterogeneous adaptive outcomes across the autism spectrum; however, the current literature remains limited in elucidating turning points and associated factors for longitudinal variability (chronogeneity). To address these empirical gaps, we aimed to provide a finer‐grained characterization of trajectories of adaptive functioning from early childhood to adolescence in autism. Methods Our sample (N = 406) was drawn from an inception cohort of children diagnosed Autistic at ages 2–5. Adaptive functioning was assessed with Vineland Adaptive Behavior Scales (VABS, 2 nd Edition) across 6 visits from the time of diagnosis by age 18. Parallel‐process latent growth curve modeling were used to estimate domain‐level VABS trajectories, followed by latent class growth analysis to identify trajectory subgroups. Child characteristics at diagnosis, family demographics, and participation outcomes at adolescence were compared across subgroups. Results Piecewise latent growth models best described VABS trajectories with two turning points identified at around ages 5‐6 and 9–10, respectively reflecting transitions into school age and early adolescence. We parsed four VABS trajectory subgroups that vary by level of functioning and change rate for certain domains and periods. Around 16% of the sample exhibited overall adequate functioning (standard score >85) with notable early growth and social adaptation during adolescence. About 21% showed low adaptive functioning (standard score ≤70), with decreasing slopes by age 6 followed by improvements in communication and daily‐living skills by age 10. The other two subgroups (63% in total) were characterized by adaptive functioning between low and adequate levels, with relatively stable trajectories entering school age. These subgroups differed most in their cognitive ability at diagnosis, household income, and social participation in adolescence. Conclusions We identified key individual and family characteristics and time windows associated with distinct adaptive functioning trajectories, which have important implications for providing timely and tailored supports to Autistic people across developmental stages.

Bibliography cited by this reference

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Cited bibliography overview

These indicators describe the bibliography cited by this publication. An author name is counted each time it appears in one cited reference, so the same person can be counted more than once. Names not yet linked to an author already present in AutiHub are treated as unknown, not as non-autistic. Last computed: 2 Oct 2026 01:40.

Cited references
86
With a DOI
83
Without a DOI, from raw bibliography text
3
2 / 86 (2.3%) cited references include at least one author identified as autistic.
References with data to complete
1 / 86 (1.2%)
References with detected author names
85 / 86 (98.8%)
Without detected author names
1
Without a structured title
1
Without a stable identifier
3
References with raw author names still to review
1
References with external metadata lookup issues
0
These indicators apply to cited references displayed on this page, after technical duplicates have been merged. A reference without a DOI can still support author statistics when a title and author names are available.
Author names detected in the cited bibliography
568
From DOI or external metadata
568
From validated raw bibliography text
0
Raw names already validated
0
Raw names still to review
1
267 / 568 (47.0%) names are linked to an author already present in AutiHub. 301 / 568 (53.0%) names are not yet linked.
Names linked to a person identified as autistic
3 / 568 (0.5%)
Calculated across all author names detected in the cited bibliography. Among names linked to an author already present in AutiHub: 3 / 267 (1.1%). Distinct people identified as autistic: 2 / 379 (0.5%).
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