Les indicateurs comportementaux et physiologiques de l'anxiété reflètent des profils communs et distincts chez des individus atteints de syndromes neurogénétiques

Titre original en anglais : Behavioural and physiological indicators of anxiety reflect shared and distinct profiles across individuals with neurogenetic syndromes

Cette publication est incluse dans le projet « Contributions académiques de personnes autistes sur l’autisme ». un auteur·ice de cette publication est identifié·e comme autiste dans le projet.

À propos de la mention auteur·ice autiste

Sources de métadonnées utilisées pour cette référence

OpenAlex Crossref PubMed OpenCitations
En savoir plus sur les sources utilisées

Crawford, H., Oliver, C., Groves, L., Bradley, L., Smith, K., Hogan, A., Renshaw, D., Waite, J., & Roberts, J. (2023). Behavioural and physiological indicators of anxiety reflect shared and distinct profiles across individuals with neurogenetic syndromes. Psychiatry Research, 326, 115278. https://doi.org/10.1016/j.psychres.2023.115278

Date de publication: 31/05/2023 Ajout dans AutiHub: 26/09/2026 Type: Article Langue de l’article: Anglais
Source éditeur (DOI) Texte intégral Source OpenAlex

Cette publication est intégrée dans AutiHub via :

Auteurs

Auteur·ices des publications
9
Auteur·ices de la publication identifié·es comme autistes
1 / 9 (11,1 %)
  1. Hayley Crawford
  2. Chris Oliver
  3. Laura Groves
  4. Louise Bradley
  5. Kayla Smith *
  1. Abigail Hogan
  2. Derek Renshaw
  3. Jane Waite
  4. Jane Roberts

Résumé

L’anxiété est accrue chez les personnes présentant une déficience intellectuelle, en particulier chez celles atteintes de syndromes neurogénétiques spécifiques. L’évaluation de l’anxiété chez ces personnes est entravée par le manque de mesures appropriées tenant compte des troubles de la communication, des différences de présentation et des caractéristiques qui se chevauchent avec des affections concomitantes. Ici, nous adoptons une approche multiméthode afin d’identifier des réponses comportementales et physiologiques fines (par le cortisol salivaire) aux sollicitations anxiogènes chez des personnes atteintes du syndrome de l’X fragile (FXS ; n = 27 ; Mage = 20,11 ans ; étendue 6,32 - 47,04 ans) et du syndrome de Cornelia de Lange (CdLS ; n = 27 ; Mage = 18,42 ans ; étendue 4,28 - 41,08 ans), deux groupes neurogénétiques à haut risque d’anxiété, comparativement à des enfants neurotypiques (NT ; n = 21 ; Mage = 5,97 ans ; étendue 4,34 - 7,30 ans). Les résultats indiquent que l’évitement physique des stimuli redoutés et la recherche de proximité auprès d’un adulte familier sont des indicateurs comportementaux importants d’anxiété/de stress dans le FXS et le CdLS. Une activation physiologique généralisée accrue a été identifiée dans ces groupes au moyen du cortisol salivaire. Une association entre les caractéristiques autistiques et l’anxiété était manifeste dans le groupe FXS, mais non dans le groupe CdLS, ce qui met en évidence des nuances spécifiques au syndrome dans l’association entre l’anxiété et l’autisme. Cette étude améliore la compréhension de la présentation comportementale et physiologique de l’anxiété chez les personnes présentant une déficience intellectuelle et fait progresser les développements théoriques concernant le développement et le maintien de l’anxiété à l’intersection de l’autisme.

Anxiety is heightened in individuals with intellectual disability, particularly in those with specific neurogenetic syndromes. Assessment of anxiety for these individuals is hampered by a lack of appropriate measures that cater for communication impairment, differences in presentation, and overlapping features with co-occurring conditions. Here, we adopt a multi-method approach to identify fine-grained behavioural and physiological (via salivary cortisol) responses to anxiety presses in people with fragile X (FXS; n = 27; Mage = 20.11 years; range 6.32 - 47.04 years) and Cornelia de Lange syndromes (CdLS; n = 27; Mage = 18.42 years; range 4.28 - 41.08 years), two neurogenetic groups at high risk for anxiety, compared to neurotypical children (NT; n = 21; Mage = 5.97 years; range 4.34 - 7.30 years). Results indicate that physical avoidance of feared stimuli and proximity seeking to a familiar adult are prominent behavioural indicators of anxiety/stress in FXS and CdLS. Heightened pervasive physiological arousal was identified in these groups via salivary cortisol. An association between autistic characteristics and anxiety was evident in the FXS group but not in the CdLS group pointing to syndrome-specific nuances in the association between anxiety and autism. This study furthers understanding of the behavioural and physiological presentation of anxiety in individuals with intellectual disability and progresses theoretical developments regarding the development and maintenance of anxiety at the intersection of autism.

Bibliographie citée par cette référence

Les références citées sont importées depuis des sources externes de métadonnées lorsqu’elles sont disponibles. La liste peut être partielle.

Vue d’ensemble de la bibliographie citée

Ces indicateurs décrivent la bibliographie citée par cette publication. Un nom d’auteurice est compté chaque fois qu’il apparaît dans une référence citée : une même personne peut donc être comptée plusieurs fois. Les noms qui ne sont pas encore associés à un·e auteurice déjà présent·e dans AutiHub sont traités comme inconnus, pas comme non autistes. Dernier calcul : 02/10/2026 01:01.

Références citées
72
Avec un DOI
67
Sans DOI, à partir du texte brut de la bibliographie
5
0 / 72 (0,0 %) références citées comprennent au moins une personne identifiée comme autiste.
Références avec données à compléter
1 / 72 (1,4 %)
Références avec noms d’auteurices détectés
71 / 72 (98,6 %)
Sans nom d’auteurice détecté
1
Sans titre structuré
1
Sans identifiant stable
5
Références avec noms bruts d’auteurices restant à vérifier
0
Références avec problème de récupération des métadonnées externes
0
Ces indicateurs portent sur les références citées affichées sur cette page, après fusion des doublons techniques. Une référence sans DOI peut quand même soutenir les statistiques d’auteurices lorsqu’un titre et des noms d’auteurices sont disponibles.
Noms d’auteurices détectés dans la bibliographie citée
365
À partir du DOI ou de métadonnées externes
365
À partir du texte brut validé de la bibliographie
0
Noms bruts déjà validés
0
Noms bruts restant à vérifier
0
103 / 365 (28,2 %) noms sont associés à un·e auteurice déjà présent·e dans AutiHub. 262 / 365 (71,8 %) noms ne sont pas encore associés.
Noms associés à une personne identifiée comme autiste
0 / 365 (0,0 %)
Calculé sur l’ensemble des noms d’auteurices détectés dans la bibliographie citée. Parmi les noms associés à un·e auteurice déjà présent·e dans AutiHub : 0 / 103 (0,0 %). Personnes distinctes identifiées comme autistes : 0 / 278 (0,0 %).
  1. Angelos-Miltiadis Krypotos (2015). Avoidance learning: a review of theoretical models and recent developments . Front. Behav. Neurosci., 9, 189. Frontiers Media SA.
    Type: Article DOI: 10.3389/fnbeh.2015.00189 OpenAlex: https://openalex.org/W1557738392
    Crossref OpenAlex
  2. Georgie Agar , Chloe Brown , Daniel Sutherland , Sean Coulborn , Chris Oliver , Caroline Richards (2021). Sleep disorders in rare genetic syndromes: a meta-analysis of prevalence and profile . Molecular Autism, 12(1), 18. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1186/s13229-021-00426-w OpenAlex: https://openalex.org/W3130409408
    Crossref OpenAlex OpenCitations
  3. Martin E.P. Seligman (1971). Phobias and preparedness . Behavior Therapy, 2(3), 307-320. Elsevier BV.
    Type: Article DOI: 10.1016/s0005-7894(71)80064-3 OpenAlex: https://openalex.org/W2009444840
    Crossref OpenAlex OpenCitations
  4. Susan W White , Carla A. Mazefsky , Gabriel S. Dichter , Pearl H. Chiu , John A. Richey , Thomas H. Ollendick (2014). Social‐cognitive, physiological, and neural mechanisms underlying emotion regulation impairments: understanding anxiety in autism spectrum disorder . International Journal of Developmental Neuroscience, 39(1), 22-36. Wiley.
    Type: Article DOI: 10.1016/j.ijdevneu.2014.05.012 OpenAlex: https://openalex.org/W1964527618
    Crossref OpenAlex OpenCitations
  5. Inna Arnaudova , Merel Kindt , Michael Fanselow , Tom Beckers (2017). Pathways towards the proliferation of avoidance in anxiety and implications for treatment . Behaviour Research and Therapy, 96, 3-13. Elsevier BV.
    Type: Article DOI: 10.1016/j.brat.2017.04.004 OpenAlex: https://openalex.org/W2590307765
    Crossref OpenAlex OpenCitations
  6. Caroline Richards , Christopher Jones , Laura Groves , Jo Moss , Chris Oliver (2015). Prevalence of autism spectrum disorder phenomenology in genetic disorders: a systematic review and meta-analysis . The Lancet Psychiatry, 2(10), 909-916. Elsevier BV.
    Type: Article DOI: 10.1016/s2215-0366(15)00376-4 OpenAlex: https://openalex.org/W2099011168
    Crossref OpenAlex OpenCitations
  7. Tessa C. Reardon , Kylie M. Gray , Glenn Melvin (2015). Anxiety disorders in children and adolescents with intellectual disability: Prevalence and assessment . Research in Developmental Disabilities, 36, 175-190. Elsevier BV.
    Type: Article DOI: 10.1016/j.ridd.2014.10.007 OpenAlex: https://openalex.org/W1992345595
    Crossref OpenAlex OpenCitations
  8. K. Arron , Chris Oliver , J. Moss , K. Berg , Cheryl Burbidge (2011). The prevalence and phenomenology of self‐injurious and aggressive behaviour in genetic syndromes . Journal of Intellectual Disability Research, 55(2), 109-120. Wiley.
    Type: Article DOI: 10.1111/j.1365-2788.2010.01337.x OpenAlex: https://openalex.org/W2096422792
    Crossref OpenAlex OpenCitations
  9. Shulamite A. Green , Lauren D. Berkovits , Bruce L. Baker (2015). Symptoms and Development of Anxiety in Children With or Without Intellectual Disability . Journal of Clinical Child & Adolescent Psychology, 44(1), 137-144. Informa UK Limited.
    Type: Article DOI: 10.1080/15374416.2013.873979 OpenAlex: https://openalex.org/W2150965423
    Crossref OpenAlex OpenCitations
  10. Stephen F. Olejnik , James Algina (1984). Parametric ANCOVA and the Rank Transform ANCOVA When the Data are Conditionally Non-Normal and Heteroscedastic . Journal of Educational Statistics, 9(2), 129-149. American Educational Research Association (AERA).
    Type: Article DOI: 10.3102/10769986009002129 OpenAlex: https://openalex.org/W1993954925
    Crossref OpenAlex OpenCitations
  11. Katja Beesdo-Baum , Susanne Knappe (2012). Developmental Epidemiology of Anxiety Disorders . Child and Adolescent Psychiatric Clinics of North America, 21(3), 457-478. Elsevier BV.
    Type: Article DOI: 10.1016/j.chc.2012.05.001 OpenAlex: https://openalex.org/W2148874864
    Crossref OpenAlex OpenCitations
  12. Nicholas D. Mian , Alice S. Carter , Daniel S. Pine , Lauren S. Wakschlag , Margaret J. Briggs‐Gowan (2015). Development of a novel observational measure for anxiety in young children: The Anxiety Dimensional Observation Scale . Journal of Child Psychology and Psychiatry, 56(9), 1017-1025. Wiley.
    Type: Article DOI: 10.1111/jcpp.12407 OpenAlex: https://openalex.org/W1994494100
    Crossref OpenAlex OpenCitations
  13. Gordon Blackburn-Munro , Ruth Blackburn-Munro (2003). Pain in the brain: are hormones to blame? Trends in Endocrinology & Metabolism, 14(1), 20-27. Elsevier BV.
    Type: Article DOI: 10.1016/s1043-2760(02)00004-8 OpenAlex: https://openalex.org/W2042817255
    Crossref OpenAlex OpenCitations
  14. Jane Roberts , Jordan E. Ezell , Amanda Fairchild , Jessica Klusek , Angela J. Thurman , Andrea McDuffie et al. (2018). Biobehavioral composite of social aspects of anxiety in young adults with fragile X syndrome contrasted to autism spectrum disorder . American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 177(7), 665-675. Wiley.
    Type: Article DOI: 10.1002/ajmg.b.32674 OpenAlex: https://openalex.org/W2897978860
    Crossref OpenAlex OpenCitations
  15. Jessica Hunter , Oliver Rivero‐Arias , Angel Angelov , Edward Kim , Iain Fotheringham , Jose Leal (2014). Epidemiology of fragile X syndrome: A systematic review and meta‐analysis . American Journal of Medical Genetics Part A, 164(7), 1648-1658. Wiley.
    Type: Article DOI: 10.1002/ajmg.a.36511 OpenAlex: https://openalex.org/W1994817684
    Crossref OpenAlex OpenCitations
  16. Shannon M. Blakey , Jonathan S. Abramowitz (2016). The effects of safety behaviors during exposure therapy for anxiety: Critical analysis from an inhibitory learning perspective . Clinical Psychology Review, 49, 1-15. Elsevier BV.
    Type: Article DOI: 10.1016/j.cpr.2016.07.002 OpenAlex: https://openalex.org/W2479684282
    Crossref OpenAlex OpenCitations
  17. Reymundo Lozano , Talia Thompson , Jayne Dixon-Weber , Craig A. Erickson , Elizabeth Berry‐Kravis , Sara Williams et al. (2022). Observable Symptoms of Anxiety in Individuals with Fragile X Syndrome: Parent and Caregiver Perspectives . Genes, 13(9), 1660. MDPI AG.
    Type: Article DOI: 10.3390/genes13091660 OpenAlex: https://openalex.org/W4296354900
    Crossref OpenAlex OpenCitations
  18. Nicole M. Russo-Ponsaran , Jessica Yesensky , David Hessl , Elizabeth Berry‐Kravis (2014). Feasibility, Reproducibility, and Clinical Validity of the Pediatric Anxiety Rating Scale—Revised for Fragile X Syndrome . American Journal on Intellectual and Developmental Disabilities, 119(1), 1-16. Informa UK Limited.
    Type: Article DOI: 10.1352/1944-7558-119.1.1 OpenAlex: https://openalex.org/W1998232774
    Crossref OpenAlex OpenCitations
  19. Bowlby (1969). Attachment and loss: volume I: attachment, Attachment and Loss: Volume I: Attachment . London: The Hogarth Press and the Institute of Psycho-Analysis, 1.
    Type: Autre
    Crossref
  20. Hayley Crawford , Joanna Moss , Laura Groves , Robyn Dowlen , Lisa Nelson , Donna Reid et al. (2020). A Behavioural Assessment of Social Anxiety and Social Motivation in Fragile X, Cornelia de Lange and Rubinstein-Taybi Syndromes . Journal of Autism and Developmental Disorders, 50(1), 127-144. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1007/s10803-019-04232-5 OpenAlex: https://openalex.org/W2973944056
    Crossref OpenAlex OpenCitations
  21. Magne Arve Flaten , Eirik Nordmark , Åke Elden (2005). Effects of background noise on the human startle reflex and prepulse inhibition . Psychophysiology, 42(3), 298-305. Wiley.
    Type: Article DOI: 10.1111/j.1469-8986.2005.00293.x OpenAlex: https://openalex.org/W2000656410
    Crossref OpenAlex OpenCitations
  22. Natali Bozhilova , Alice Welham , Dawn Adams , Stacey Bissell , Hilgo Bruining , Hayley Crawford et al. (2023). Profiles of autism characteristics in thirteen genetic syndromes: a machine learning approach . Molecular Autism, 14(1), 3. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1186/s13229-022-00530-5 OpenAlex: https://openalex.org/W4315866063
    Crossref OpenAlex OpenCitations
  23. Anna J. Esbensen , Johannes Rojahn , Michael G. Aman , Stephen Ruedrich (2003). Reliability and Validity of an Assessment Instrument for Anxiety, Depression, and Mood Among Individuals with Mental Retardation . Journal of Autism and Developmental Disorders, 33(6), 617-629. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1023/b:jadd.0000005999.27178.55 OpenAlex: https://openalex.org/W2169266966
    Crossref OpenAlex OpenCitations
  24. Katarina Dedovic , Annie Duchesne , Julie Andrews , Veronika Engert , Jens C. Pruessner (2009). The brain and the stress axis: The neural correlates of cortisol regulation in response to stress . NeuroImage, 47(3), 864-871. Elsevier BV.
    Type: Article DOI: 10.1016/j.neuroimage.2009.05.074 OpenAlex: https://openalex.org/W2000799395
    Crossref OpenAlex OpenCitations
  25. Lee Anna Clark , David Watson (1991). Tripartite model of anxiety and depression: Psychometric evidence and taxonomic implications. Journal of Abnormal Psychology, 100(3), 316-336. American Psychological Association (APA).
    Type: Article DOI: 10.1037//0021-843x.100.3.316 OpenAlex: https://openalex.org/W2148916146
    Crossref OpenAlex OpenCitations
  26. Joanna Moss , Lisa Nelson , Laurie Powis , Jane Waite , Caroline Richards , Chris Oliver (2016). A Comparative Study of Sociability in Angelman, Cornelia de Lange, Fragile X, Down and Rubinstein Taybi Syndromes and Autism Spectrum Disorder . American Journal on Intellectual and Developmental Disabilities, 121(6), 465-486. Informa UK Limited.
    Type: Article DOI: 10.1352/1944-7558-121.6.465 OpenAlex: https://openalex.org/W2547981972
    Crossref OpenAlex OpenCitations
  27. Scott S. Hall , Amy A. Lightbody , Lynne C. Huffman , Laura C. Lazzeroni , Allan L. Reiss (2009). Physiological Correlates of Social Avoidance Behavior in Children and Adolescents With Fragile X Syndrome . Journal of the American Academy of Child & Adolescent Psychiatry, 48(3), 320-329. Elsevier BV.
    Type: Article DOI: 10.1097/chi.0b013e318195bd15 OpenAlex: https://openalex.org/W2003276089
    Crossref OpenAlex OpenCitations
  28. Constantino (2012). Social Responsiveness scale: SRS-2 . Social Responsiveness Scale (SRS-2)., 3.
    Type: Autre
    Crossref
  29. Norman B. Schmidt , J. Anthony Richey , Michael J. Zvolensky , Jon K. Maner (2008). Exploring human freeze responses to a threat stressor . Journal of Behavior Therapy and Experimental Psychiatry, 39(3), 292-304. Elsevier BV.
    Type: Article DOI: 10.1016/j.jbtep.2007.08.002 OpenAlex: https://openalex.org/W2007942589
    Crossref OpenAlex OpenCitations
  30. Lisa Cordeiro , Elizabeth Ballinger , Randi J. Hagerman , David Hessl (2011). Clinical assessment of DSM-IV anxiety disorders in fragile X syndrome: prevalence and characterization . Journal of Neurodevelopmental Disorders, 3(1), 57-67. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1007/s11689-010-9067-y OpenAlex: https://openalex.org/W2060911896
    Crossref OpenAlex OpenCitations
  31. J. Mertens , E. R. Zane , K. Neumeyer , R. B. Grossman (2017). How Anxious Do You Think I Am? Relationship Between State and Trait Anxiety in Children With and Without ASD During Social Tasks . Journal of Autism and Developmental Disorders, 47(12), 3692-3703. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1007/s10803-016-2979-y OpenAlex: https://openalex.org/W2571158533
    Crossref OpenAlex OpenCitations
  32. Hayley Crawford (2023). Social Anxiety in Neurodevelopmental Disorders: The Case of Fragile X Syndrome . American Journal on Intellectual and Developmental Disabilities, 128(4), 302-318. Informa UK Limited.
    Type: Article DOI: 10.1352/1944-7558-128.4.302 OpenAlex: https://openalex.org/W4384819433
    Crossref OpenAlex OpenCitations
  33. Connor Kerns , Breanna Winder-Patel , Ana-Maria Iosif , Christine Wu Nordahl , Brianna Heath , Marjorie Solomon et al. (2021). Clinically Significant Anxiety in Children with Autism Spectrum Disorder and Varied Intellectual Functioning . Journal of Clinical Child & Adolescent Psychology, 50(6), 780-795. Informa UK Limited.
    Type: Article DOI: 10.1080/15374416.2019.1703712 OpenAlex: https://openalex.org/W3002322091
    Crossref OpenAlex OpenCitations
  34. Jessica Klusek , Jane Roberts , Molly Losh (2015). Cardiac autonomic regulation in autism and Fragile X syndrome: A review. Psychological Bulletin, 141(1), 141-175. American Psychological Association (APA).
    Type: Article DOI: 10.1037/a0038237 OpenAlex: https://openalex.org/W2027485994
    Crossref OpenAlex OpenCitations
  35. Hayley Crawford , Leonard Abbeduto , Scott S. Hall , Rebecca Hardiman , David Hessl , Jane Roberts et al. (2020). Fragile X syndrome: an overview of cause, characteristics, assessment and management . Paediatrics and Child Health, 30(11), 400-403. Elsevier BV.
    Type: Article DOI: 10.1016/j.paed.2020.08.007 OpenAlex: https://openalex.org/W3082892902
    Crossref OpenAlex OpenCitations
  36. Dan J. Stein , Kate M. Scott , Peter de Jonge , Ronald C. Kessler (2017). Epidemiology of anxiety disorders: from surveys to nosology and back . Dialogues in Clinical Neuroscience, 19(2), 127-136. Informa UK Limited.
    Type: Article DOI: 10.31887/dcns.2017.19.2/dstein OpenAlex: https://openalex.org/W2758572380
    Crossref OpenAlex OpenCitations
  37. Chris Oliver , Katy Berg , Jo Moss , Kate Arron , Cheryl Burbidge (2011). Delineation of Behavioral Phenotypes in Genetic Syndromes: Characteristics of Autism Spectrum Disorder, Affect and Hyperactivity . Journal of Autism and Developmental Disorders, 41(8), 1019-1032. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1007/s10803-010-1125-5 OpenAlex: https://openalex.org/W2045116979
    Crossref OpenAlex OpenCitations
  38. Hayley Crawford , Jane Waite , Chris Oliver (2017). Diverse Profiles of Anxiety Related Disorders in Fragile X, Cornelia de Lange and Rubinstein–Taybi Syndromes . Journal of Autism and Developmental Disorders, 47(12), 3728-3740. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1007/s10803-016-3015-y OpenAlex: https://openalex.org/W2584350965
    Crossref OpenAlex OpenCitations
  39. Jordan Ezell , Abigail Hogan , Amanda Fairchild , Kimberly J Hills , Jessica Klusek , Leonard Abbeduto et al. (2019). Prevalence and Predictors of Anxiety Disorders in Adolescent and Adult Males with Autism Spectrum Disorder and Fragile X Syndrome . Journal of Autism and Developmental Disorders, 49(3), 1131-1141. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1007/s10803-018-3804-6 OpenAlex: https://openalex.org/W2898471971
    Crossref OpenAlex OpenCitations
  40. Jacqui Rodgers , M. Glod , B. Connolly , Helen McConachie (2012). The Relationship Between Anxiety and Repetitive Behaviours in Autism Spectrum Disorder . Journal of Autism and Developmental Disorders, 42(11), 2404-2409. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1007/s10803-012-1531-y OpenAlex: https://openalex.org/W2141257736
    Crossref OpenAlex OpenCitations
  41. Victor B. Talisa , Lia Boyle , Daina Crafa , Walter E. Kaufmann (2014). Autism and anxiety in males with fragile X syndrome: An exploratory analysis of neurobehavioral profiles from a parent survey . American Journal of Medical Genetics Part A, 164(5), 1198-1203. Wiley.
    Type: Article DOI: 10.1002/ajmg.a.36468 OpenAlex: https://openalex.org/W2066015718
    Crossref OpenAlex OpenCitations
  42. Dunn (2009). The British Picture Vocabulary Scale III .
    Type: Autre
    Crossref
  43. Kate Woodcock , Chris Oliver , G. Humphreys (2009). Associations between repetitive questioning, resistance to change, temper outbursts and anxiety in Prader–Willi and Fragile‐X syndromes . Journal of Intellectual Disability Research, 53(3), 265-278. Wiley.
    Type: Article DOI: 10.1111/j.1365-2788.2008.01122.x OpenAlex: https://openalex.org/W2074610241
    Crossref OpenAlex OpenCitations
  44. Georgina Edwards , Chris Jones , Effie Pearson , Rachel Royston , Chris Oliver , Joanne Tarver et al. (2022). Prevalence of anxiety symptomatology and diagnosis in syndromic intellectual disability: A systematic review and meta-analysis . Neuroscience & Biobehavioral Reviews, 138, 104719. Elsevier BV.
    Type: Article DOI: 10.1016/j.neubiorev.2022.104719 OpenAlex: https://openalex.org/W4281729570
    Crossref OpenAlex OpenCitations
  45. Joanna Moss , Chris Oliver , Kate Arron , Cheryl Burbidge , Katy Berg (2009). The Prevalence and Phenomenology of Repetitive Behavior in Genetic Syndromes . Journal of Autism and Developmental Disorders, 39(4), 572-588. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1007/s10803-008-0655-6 OpenAlex: https://openalex.org/W2076723359
    Crossref OpenAlex OpenCitations
  46. Georgina Edwards , Joanne Tarver , Lauren Shelley , Megan Bird , Jessica Hughes , Hayley Crawford et al. (2023). Utilising Interview Methodology to Inform the Development of New Clinical Assessment Tools for Anxiety in Autistic Individuals Who Speak Few or no Words . J. Autism Dev. Disord., 53(6), 1. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1007/s10803-022-05509-y OpenAlex: https://openalex.org/W4220930078
    Crossref OpenAlex
  47. Ludovica Giani , Giovanni Michelini , Maria Nobile , Paola Francesca Ajmone , Paola Giovanna Vizziello , Simona Scaini (2022). Behavioral markers of social anxiety in Cornelia de Lange Syndrome: A brief systematic review . Journal of Affective Disorders, 299, 636-643. Elsevier BV.
    Type: Article DOI: 10.1016/j.jad.2021.12.099 OpenAlex: https://openalex.org/W4200068073
    Crossref OpenAlex OpenCitations
  48. Norman S Endler , Nancy L Kocovski (2001). State and trait anxiety revisited . Journal of Anxiety Disorders, 15(3), 231-245. Elsevier BV.
    Type: Article DOI: 10.1016/s0887-6185(01)00060-3 OpenAlex: https://openalex.org/W2077880694
    Crossref OpenAlex OpenCitations
  49. Eric Emerson , Chris Hatton (2007). Mental health of children and adolescents with intellectual disabilities in Britain . British Journal of Psychiatry, 191(6), 493-499. Royal College of Psychiatrists.
    Type: Article DOI: 10.1192/bjp.bp.107.038729 OpenAlex: https://openalex.org/W2124778889
    Crossref OpenAlex OpenCitations
  50. Laura Groves , Joanna Moss , Chris Oliver , Rachel Royston , Jane Waite , Hayley Crawford (2022). Divergent presentation of anxiety in high-risk groups within the intellectual disability population . Journal of Neurodevelopmental Disorders, 14(1), 54. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1186/s11689-022-09462-w OpenAlex: https://openalex.org/W4302010938
    Crossref OpenAlex OpenCitations
  51. Jane Roberts , Megan A. Clarke , Kaitlyn Alcorn , John C. Carter , Anna C. J. Long , Walter E. Kaufmann (2009). Autistic behavior in boys with fragile X syndrome: social approach and HPA-axis dysfunction . J. Neurodev. Disord., 1(4), 283. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1007/s11689-009-9028-5 OpenAlex: https://openalex.org/W2115422888
    Crossref OpenAlex
  52. B. H. Esbjørn , P. K. Bender , M. L. Reinholdt-Dunne , L. A. Munck , Thomas H. Ollendick (2012). The Development of Anxiety Disorders: Considering the Contributions of Attachment and Emotion Regulation . Clinical Child and Family Psychology Review, 15(2), 129-143. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1007/s10567-011-0105-4 OpenAlex: https://openalex.org/W2158118444
    Crossref OpenAlex OpenCitations
  53. Michael W. Eysenck , Małgorzata Fajkowska (2018). Anxiety and depression: toward overlapping and distinctive features . Cognition and Emotion, 32(7), 1391-1400. Informa UK Limited.
    Type: Article DOI: 10.1080/02699931.2017.1330255 OpenAlex: https://openalex.org/W2626325039
    Crossref OpenAlex OpenCitations
  54. Laura Groves , Chris Oliver , Joanna Moss (2021). Behaviour across the lifespan in Cornelia de Lange syndrome . Current Opinion in Psychiatry, 34(2), 112-117. Ovid Technologies (Wolters Kluwer Health).
    Type: Article DOI: 10.1097/yco.0000000000000671 OpenAlex: https://openalex.org/W3110689188
    Crossref OpenAlex OpenCitations
  55. Scott Hall , Marie DeBernardis , Allan Reiss (2006). Social Escape Behaviors in Children with Fragile X Syndrome . Journal of Autism and Developmental Disorders, 36(7), 935-947. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1007/s10803-006-0132-z OpenAlex: https://openalex.org/W2141730098
    Crossref OpenAlex OpenCitations
  56. Samantha Flynn , Leen Vereenooghe , Richard P. Hastings , Dawn Adams , Sally-Ann Cooper , Nick Gore et al. (2017). Measurement tools for mental health problems and mental well-being in people with severe or profound intellectual disabilities: A systematic review . Clinical Psychology Review, 57, 32-44. Elsevier BV.
    Type: Article DOI: 10.1016/j.cpr.2017.08.006 OpenAlex: https://openalex.org/W2744373844
    Crossref OpenAlex OpenCitations
  57. Laura Groves , Joanna Moss , Hayley Crawford , Lisa Nelson , Chris Stinton , Gursharan Singla et al. (2019). Lifespan trajectory of affect in Cornelia de Lange syndrome: towards a neurobiological hypothesis . Journal of Neurodevelopmental Disorders, 11(1), 6-6. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1186/s11689-019-9269-x OpenAlex: https://openalex.org/W2948864095
    Crossref OpenAlex OpenCitations
  58. Ned H. Kalin , Steven E. Shelton , Maureen Rickman , Richard J. Davidson (1998). Individual differences in freezing and cortisol in infant and mother rhesus monkeys. Behavioral Neuroscience, 112(1), 251-254. American Psychological Association (APA).
    Type: Article DOI: 10.1037/0735-7044.112.1.251 OpenAlex: https://openalex.org/W2154843838
    Crossref OpenAlex OpenCitations
  59. Jane Roberts , Jessica Bradshaw , Elizabeth A Will , Abigail Hogan , Samuel McQuillin , Kimberly J Hills (2020). Emergence and rate of autism in fragile X syndrome across the first years of life . Development and Psychopathology, 32(4), 1335-1352. Cambridge University Press (CUP).
    Type: Article DOI: 10.1017/s0954579420000942 OpenAlex: https://openalex.org/W3104878055
    Crossref OpenAlex OpenCitations
  60. Susan H. Spence , Ron Rapee (2016). The etiology of social anxiety disorder: An evidence-based model . Behaviour Research and Therapy, 86, 50-67. Elsevier BV.
    Type: Article DOI: 10.1016/j.brat.2016.06.007 OpenAlex: https://openalex.org/W2473225829
    Crossref OpenAlex OpenCitations
  61. D Hessl , B Glaser , J Dyer-Friedman , C Blasey , T Hastie , M Gunnar et al. (2002). Cortisol and behavior in fragile X syndrome . Psychoneuroendocrinology, 27(7), 855-872. Elsevier BV.
    Type: Article DOI: 10.1016/s0306-4530(01)00087-7 OpenAlex: https://openalex.org/W2164784263
    Crossref OpenAlex OpenCitations
  62. Cynthia Suveg , Diana Morelen , Gene A. Brewer , Kristel Thomassin (2010). The Emotion Dysregulation Model of Anxiety: A preliminary path analytic examination . Journal of Anxiety Disorders, 24(8), 924-930. Elsevier BV.
    Type: Article DOI: 10.1016/j.janxdis.2010.06.018 OpenAlex: https://openalex.org/W2168148986
    Crossref OpenAlex OpenCitations
  63. Antonie D. Kline , Joanna F. Moss , Angelo Selicorni , Anne-Marie Bisgaard , Matthew A. Deardorff , Peter M. Gillett et al. (2018). Diagnosis and management of Cornelia de Lange syndrome: first international consensus statement . Nature Reviews Genetics, 19(10), 649-666. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1038/s41576-018-0031-0 OpenAlex: https://openalex.org/W2871213110
    Crossref OpenAlex OpenCitations
  64. Stefan G. Hofmann , Aleena C. Hay (2018). Rethinking avoidance: Toward a balanced approach to avoidance in treating anxiety disorders . Journal of Anxiety Disorders, 55, 14-21. Elsevier BV.
    Type: Article DOI: 10.1016/j.janxdis.2018.03.004 OpenAlex: https://openalex.org/W2794075201
    Crossref OpenAlex OpenCitations
  65. Jennie Hudson , Kou Murayama , Lotte Meteyard , Talia Morris , Helen F. Dodd (2019). Early Childhood Predictors of Anxiety in Early Adolescence . Journal of Abnormal Child Psychology, 47(7), 1121-1133. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1007/s10802-018-0495-6 OpenAlex: https://openalex.org/W2905121047
    Crossref OpenAlex OpenCitations
  66. (s. d.). Hogan, A., Smith, K., Mian, N. D., Black, C., Hunt, E., Knott, C., Moser, C., Smith, J., Caravella, K., Hills, K., Fairchild, A., Carter, A. S., Roberts, J., under review. Utility of the Modified Anxiety Dimensional Observation Scale (M-Anx-DOS) in Autistic Preschoolers. J. Clinic. Child Adoles. Psychol..
    Type: Autre
    Crossref
  67. Jane Roberts , Megan A. Clarke , Kaitlyn Alcorn , John C. Carter , Anna C. J. Long , Walter E. Kaufmann (2009). Autistic behavior in boys with fragile X syndrome: social approach and HPA-axis dysfunction . Journal of Neurodevelopmental Disorders, 1(4), 283-291. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1007/s11689-009-9028-5 10.17615/nhqa-dv54
    OpenCitations
  68. Sara M. Matherly , Jessica Klusek , Angela J. Thurman , Andrea McDuffie , Leonard Abbeduto , Jane Roberts (2018). Cortisol profiles differentiated in adolescents and young adult males with fragile X syndrome versus autism spectrum disorder . Developmental Psychobiology, 60(1), 78-89. Wiley.
    Type: Article DOI: 10.1002/dev.21578 OpenAlex: https://openalex.org/W2768252879
    Crossref OpenAlex OpenCitations
  69. Peter J. Norton , Daniel J. Paulus (2017). Transdiagnostic models of anxiety disorder: Theoretical and empirical underpinnings . Clinical Psychology Review, 56, 122-137. Elsevier BV.
    Type: Article DOI: 10.1016/j.cpr.2017.03.004 OpenAlex: https://openalex.org/W2600378660
    Crossref OpenAlex OpenCitations
  70. Bridgette Kelleher , Jessica Scherr , Debra Reisinger , Jane Roberts (2017). Behavioral Markers of Emergent Stranger Anxiety in Infants and Toddlers with Fragile X Syndrome . Journal of Autism and Developmental Disorders, 47(11), 3646-3658. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1007/s10803-017-3270-6 OpenAlex: https://openalex.org/W2753537926
    Crossref OpenAlex OpenCitations
  71. Lisa Nelson , Hayley Crawford , Donna Reid , Joanna Moss , Chris Oliver (2017). An experimental study of executive function and social impairment in Cornelia de Lange syndrome . Journal of Neurodevelopmental Disorders, 9(1), 33-33. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1186/s11689-017-9213-x OpenAlex: https://openalex.org/W2746050465
    Crossref OpenAlex OpenCitations
  72. Sparrow (2005). Vineland-II Adaptive Behavior Scales: Survey Forms Manual .
    Type: Autre
    Crossref