Low-intensity parent- and clinician-delivered support for young autistic children in Aotearoa New Zealand: a randomised controlled trial

Waddington, H., Jordan, P., Hammond, M. D., Tupou, J., Patrick, L., Macaskill, E., Davies, G., Pillar, S., Meer, L. v. d., & Whitehouse, A. (2024). Low-intensity parent- and clinician-delivered support for young autistic children in Aotearoa New Zealand: a randomised controlled trial. The Lancet Regional Health - Western Pacific, 51, 101173. https://doi.org/10.1016/j.lanwpc.2024.101173

Publication date: 16 Aug 2024 Added to AutiHub: 6 Jul 2026 Type: Article Article language: English

This publication is integrated into AutiHub through:

Authors

Publication authors
10
Publication authors identified as autistic
1 / 10 (10.0%)

Abstract

Background Aotearoa New Zealand does not provide publicly-funded intensive autism support. While parent-mediated supports are promising, children and families may also benefit from direct clinician support. We tested the efficacy of a low-intensity programme involving parent- and clinician-delivered support for autistic children. Methods This single-blind, two-arm randomised controlled trial assessed outcomes of a six-month low-intensity parent- and clinician-delivered support (2–3 h per week) based on the Early Start Denver Model compared to a control group who received monthly support calls and assistance with referrals. Children aged 1–4.5 years who were autistic or showing signs of autism and their parents were randomised to the low-intensity or control group by a blinded statistician using the Urn minimisation method. Assessments were conducted at baseline and immediately following the support period (24-weeks post-baseline). The primary outcome was child engagement during an interaction with their parent. The trial was pre-registered with ANZCTR: U1111-1260-2529. Findings From March 2021 to May 2023, 56 families were randomised to either the low-intensity or control group. Following drop-outs, 21 families in the low-intensity group and 24 in the control group were included in analysis. There was large and significantly greater improvement in children's engagement in the low-intensity group compared to the control group (F (1, 43) = 21.47, p < 0.0001, η p 2 = 0.33). There was one recorded adverse event unrelated to the support and two adverse effects related to the support. Interpretation A low-intensity parent- and clinician-delivered support can improve engagement between an autistic child and their parent during play. Low-intensity supports may be beneficial in areas where access to clinical autism supports is limited. Funding Emerging Researcher First Grant from the Health Research Council of New Zealand.

Bibliography cited by this reference

Cited references are imported from external metadata sources when they are available. The list may be partial.

Bibliography inclusion overview

These indicators describe the cited bibliography imported for this publication. Cited-reference metrics use the cited-reference total as denominator. Cited-author metrics state whether they use all cited-author occurrences or only occurrences linked to authors already integrated in the AutiHub database. They use cached links between cited authors and authors integrated in the AutiHub database. Last computed: 16 Aug 2026 11:31.

Cited references
38
Total cited references integrated for this publication.
Cited references with an identified autistic author
2 / 38 (5.3%)
Cited author occurrences identified as autistic
3 / 184 (1.6%)
Among occurrences linked to AutiHub author records: 3 / 52 (5.8%). Distinct cited authors identified as autistic: 3 / 159 (1.9%).
Cited author occurrences linked to AutiHub author records
52 / 184 (28.3%)
Distinct linked cited authors: 36 / 159 (22.6%)
Linked cited-author occurrences not identified as autistic
49 / 52 (94.2%)
Among linked cited-author occurrences only. Across all cited-author occurrences: 49 / 184 (26.6%). Distinct linked cited authors not identified as autistic: 33 / 36 (91.7%).
2 cited bibliography entries could not be fully enriched from DOI metadata.
Crossref: not found (1) · DataCite: not found (1)
  1. X. Hu , J. A. Summers , A. Turnbull , N. Zuna (2011). The quantitative measurement of family quality of life: a review of available instruments . Journal of Intellectual Disability Research, 55(12), 1098-1114. Wiley.
    Crossref OpenAlex OpenCitations
  2. Charlotte Engberg Conrad , Marie Louise Rimestad , Jeanett Friis Rohde , Birgitte Holm Petersen , Christoffer Bruun Korfitsen , Simon Tarp et al. (2021). Parent-Mediated Interventions for Children and Adolescents With Autism Spectrum Disorders: A Systematic Review and Meta-Analysis . Frontiers in Psychiatry, 12, 773604-773604. Frontiers Media SA.
    Crossref OpenAlex OpenCitations
  3. Patricia Howlin (2011). Early Start Denver Model for Young Children with Autism: Promoting Language, Learning, and Engagement . Child and Adolescent Mental Health, 16(2), 128-128. Wiley.
    OpenAlex
  4. Micheal Sandbank , Kristen Bottema‐Beutel , Shannon Crowley , Jacob I. Feldman , D. Jonah Barrett , Nicolette Caldwell et al. (2023). Autism intervention meta-analysis of early childhood studies (Project AIM): updated systematic review and secondary analysis . BMJ, 383, e076733. BMJ.
    Crossref OpenAlex
  5. Louisa M. T. Silva , Mark Schalock (2012). Autism Parenting Stress Index: Initial Psychometric Evidence . Journal of Autism and Developmental Disorders, 42(4), 566-574. Springer Science and Business Media LLC.
    Crossref OpenAlex OpenCitations
  6. Amy M. Wetherby , Whitney Guthrie , Juliann Woods , Christopher Schatschneider , Renee D. Holland , Lindee Morgan et al. (2014). Parent-Implemented Social Intervention for Toddlers With Autism: An RCT . Pediatrics, 134(6), 1084-1093. American Academy of Pediatrics (AAP).
    Crossref OpenAlex OpenCitations
  7. van der Meer (2023). How do we get autism support right in Aotearoa New Zealand? Final Report .
    Type: Other
    Crossref
  8. Carla Wallace-Watkin , Andrew Whitehouse , Hannah Waddington (2021). Early Intervention Delivery Methods for New Zealand Children with Autism: Current Practices Versus Parental Preferences . Journal of Autism and Developmental Disorders, 51(9), 3199-3211. Springer Science and Business Media LLC.
    Crossref OpenAlex OpenCitations
  9. Rhiannon Luyster , Katherine Gotham , Whitney Guthrie , Mia Coffing , Rachel Petrak , Karen Pierce et al. (2009). The Autism Diagnostic Observation Schedule—Toddler Module: A New Module of a Standardized Diagnostic Measure for Autism Spectrum Disorders . Journal of Autism and Developmental Disorders, 39(9), 1305-1320. Springer Science and Business Media LLC.
    Crossref OpenAlex OpenCitations
  10. (2024). Human development report 2023-24: Breaking the gridlock: reimagining cooperation in a polarized world .
    Type: Other
    Crossref
  11. Yanyan Yang , Hongan Wang , Haiping Xu , Meiling Yao , Dongchuan Yu (2023). Randomized, controlled trial of a mixed early start Denver model for toddlers and preschoolers with autism . Autism Research, 16(8), 1640-1649. Wiley.
    Type: Article DOI: 10.1002/aur.3006 OpenAlex: https://openalex.org/W4385752189
    Crossref OpenAlex OpenCitations
  12. Sharon Bradley‐Johnson (1997). Mullen Scales of Early Learning . Psychology in the Schools, 34(4), 379-382.
    Type: Article DOI: 10.1002/(sici)1520-6807(199710)34:4 OpenAlex: https://openalex.org/W2037716870 Crossref: not found DataCite: not found
    OpenAlex
  13. Nilushini Kasilingam , Hannah Waddington , Larah van der Meer (2021). Early Intervention for Children with Autism Spectrum Disorder in New Zealand: What Children Get and What Parents Want . International Journal of Disability, Development and Education, 68(4), 521-537. Informa UK Limited.
    Crossref OpenAlex OpenCitations
  14. Jonathan Green , Tony Charman , Helen McConachie , Catherine Aldred , Vicky Slonims , Patricia Howlin et al. (2010). Parent-mediated communication-focused treatment in children with autism (PACT): a randomised controlled trial . The Lancet, 375(9732), 2152-2160. Elsevier BV.
    Crossref OpenAlex OpenCitations
  15. Roger Bakeman , Lauren B. Adamson (1984). Coordinating Attention to People and Objects in Mother-Infant and Peer-Infant Interaction . Child Development, 55(4), 1278. Oxford University Press (OUP).
    Type: Article DOI: 10.2307/1129997 OpenAlex: https://openalex.org/W2039124909
    Crossref OpenAlex OpenCitations
  16. Géraldine Dawson , Sally J. Rogers , Jeffrey Munson , Milani Smith , Jamie Winter , Jessica Greenson et al. (2010). Randomized, Controlled Trial of an Intervention for Toddlers With Autism: The Early Start Denver Model . Pediatrics, 125(1), e17-e23. American Academy of Pediatrics (AAP).
    Crossref OpenAlex OpenCitations
  17. Charlotte Johnston , Eric J. Mash (1989). A Measure of Parenting Satisfaction and Efficacy . Journal of Clinical Child Psychology, 18(2), 167-175. Informa UK Limited.
    Crossref OpenAlex OpenCitations
  18. Jessica A. Brian , Isabel M. Smith , Lonnie Zwaigenbaum , Susan E. Bryson (2017). Cross‐site randomized control trial of the Social ABCs caregiver‐mediated intervention for toddlers with autism spectrum disorder . Autism Research, 10(10), 1700-1711. Wiley.
    Type: Article DOI: 10.1002/aur.1818 OpenAlex: https://openalex.org/W2621066334
    Crossref OpenAlex OpenCitations
  19. Thomas M. Reimers , David P. Wacker , Linda J. Cooper , Agnes O. Deraad (1992). Clinical Evaluation of the Variables associated with Treatment Acceptability and Their Relation to Compliance . Behavioral Disorders, 18(1), 67-76. SAGE Publications.
    Crossref OpenAlex OpenCitations
  20. L.J. Wei , John M. Lachin (1988). Properties of the urn randomization in clinical trials . Controlled Clinical Trials, 9(4), 345-364. Elsevier BV.
    Crossref OpenAlex OpenCitations
  21. Jonathan Green , Kathy Leadbitter , Ceri Ellis , Lauren Taylor , Heather L. Moore , Sophie Carruthers et al. (2022). Combined social communication therapy at home and in education for young autistic children in England (PACT-G): a parallel, single-blind, randomised controlled trial . The Lancet Psychiatry, 9(4), 307-320. Elsevier BV.
    Crossref OpenAlex OpenCitations
  22. Lucie Jurek , Kathy Leadbitter , Bruno Falissard , Cyrille Colin , Sandrine Touzet , Marie-Maude Geoffray (2023). Parental experience of parent-mediated intervention for children with ASD: A systematic review and qualitative evidence synthesis . Autism, 27(3), 647-666. SAGE Publications.
    Crossref OpenAlex OpenCitations
  23. Terry K. Koo , Mae Y. Li (2016). A Guideline of Selecting and Reporting Intraclass Correlation Coefficients for Reliability Research . Journal of Chiropractic Medicine, 15(2), 155-163. National University of Health Sciences.
    Crossref OpenAlex
  24. Stephanie Y. Shire , Ya‐Chih Chang , Wendy Shih , Suzanne Bracaglia , Maria Kodjoe , Connie Kasari (2017). Hybrid implementation model of community‐partnered early intervention for toddlers with autism: a randomized trial . Journal of Child Psychology and Psychiatry, 58(5), 612-622. Wiley.
    Crossref OpenAlex OpenCitations
  25. Sally J. Rogers , Annette Estes , Catherine Lord , Jeff Munson , Marie Rocha , Jamie Winter et al. (2019). A Multisite Randomized Controlled Two-Phase Trial of the Early Start Denver Model Compared to Treatment as Usual . Journal of the American Academy of Child & Adolescent Psychiatry, 58(9), 853-865. Elsevier BV.
    Crossref OpenAlex OpenCitations
  26. Rogers (2010). Early start Denver model for young children with autism: promoting language, learning, and engagement .
    Type: Other
    Crossref
  27. Zhi Wang , Sau Cheong Loh , Jing Tian , Qian Jiang Chen (2022). A meta-analysis of the effect of the Early Start Denver Model in children with autism spectrum disorder . International Journal of Developmental Disabilities, 68(5), 587-597. Informa UK Limited.
    Crossref OpenAlex OpenCitations
  28. Bethany A. Vibert , Sarah Dufek , Claire B. Klein , Yeo Bi Choi , Jamie Winter , Catherine Lord et al. (2020). Quantifying Caregiver Change Across Early Autism Interventions Using the Measure of NDBI Strategy Implementation: Caregiver Change (MONSI-CC) . Journal of Autism and Developmental Disorders, 50(4), 1364-1379. Springer Science and Business Media LLC.
    Crossref OpenAlex OpenCitations
  29. Atheendar S. Venkataramani , Kristen Underhill , Kevin G. Volpp (2020). Moving Toward Evidence-Based Policy . JAMA, 323(1), 21. American Medical Association (AMA).
    Crossref OpenAlex OpenCitations
  30. Lord (2012). Autism diagnostic observation schedule, second edition (ADOS-2) manual (part I): modules 1-4 . Autism Diagnostic Observation Schedule, Second Edition (ADOS-2) Manual (Part I): Modules 1-4..
    Type: Other
    Crossref
  31. Mihaela D. Barokova , Chelsea La Valle , Sommer Hassan , Collin Lee , Mengyuan Xu , Riley McKechnie et al. (2021). Eliciting Language Samples for Analysis (ELSA ): A New Protocol for Assessing Expressive Language and Communication in Autism . Autism Research, 14(1), 112-126. Wiley.
    Type: Article DOI: 10.1002/aur.2380 OpenAlex: https://openalex.org/W3084704861
    Crossref OpenAlex
  32. Rogers (2021). Coaching parents of young children with autism: promoting connection, communication, and learning .
    Type: Other
    Crossref
  33. Howard A. Paul (2022). Coaching Parents of Young Children with Autism: Promoting Connection, Communication, and Learning. Child & Family Behavior Therapy, 44(1), 60-66. Informa UK Limited.
    OpenAlex
  34. Mullen (1995). Mullen Scales of Early Learning . Mullen Scales of Early Learning..
    Type: Other
    Crossref
  35. Sparrow (2016). Vineland-3: Vineland adaptive behavior scales .
    Type: Other
    Crossref
  36. Constantino (2012). Social responsiveness scale–2nd ed. (SRS-2) .
    Type: Other
    Crossref