Billets de Michelle Dawson

Billet publié sur Twitter/X le 21/02/2013 06:03

Retour aux billets Billet précédent Billet suivant
Twitter/X Publication avec DOI crossref Lien intégré au billet Termes sur l’autisme
Ouvrir le billet original

Infos sur les liens intégrés au billet

Publication avec DOI

Mehmet Akif Coskun, Katherine A. Loveland, Deborah A. Pearson, Andrew C. Papanicolaou, Bhavin R. Sheth (2013). Functional Assays of Local Connectivity in the Somatosensory Cortex of Individuals with Autism. Autism Research, 6(3), 190-200. Wiley.

Plus d’infos
Publication avec DOI

Michael A. Grubb, Marlene Behrmann, Ryan Egan, Nancy J. Minshew, Marisa Carrasco, David J. Heeger (2013). Endogenous Spatial Attention: Evidence for Intact Functioning in Adults With Autism. Autism Research, 6(2), 108-118. Wiley.

Plus d’infos

Liens cités structurés

2 ressources citées

Publication avec DOI Récupéré Publication crossref

Mehmet Akif Coskun, Katherine A. Loveland, Deborah A. Pearson, Andrew C. Papanicolaou, Bhavin R. Sheth (2013). Functional Assays of Local Connectivity in the Somatosensory Cortex of Individuals with Autism. Autism Research, 6(3), 190-200. Wiley.

Date de publication
20/02/2013
Identifiant
10.1002/aur.1276
Auteurs
Mehmet Akif Coskun, Katherine A. Loveland, Deborah A. Pearson, Andrew C. Papanicolaou, Bhavin R. Sheth
Source
Autism Research
Détails
6(3), 190-200
Type de référence
article
Éditeur
Wiley
Source de métadonnées
crossref

Résumé

Emerging evidence for differences between individuals with autism spectrum disorder (ASD ) and neurotypical (NT ) individuals in somatic processing and brain response to touch suggests somatosensory cortex as a promising substrate for elucidating differences in functional brain connectivity between individuals with and without autism. Signals from adjacent digits project to neighboring locations or representations in somatosensory cortex. When a digit is stimulated, i.e. touched, its representation in cortex is directly activated; local intracortical connections indirectly activate nonprimary cortical representations corresponding to adjacent digits. The response of the nonprimary cortical representations is thus a proxy for connection strength. Local overconnectivity in autism implies that the nonprimary/primary response ratios of the ASD group will be higher than those of the NT group. D 1 and D 2 of the dominant hand of the participant were individually stimulated while we recorded neural responses using magnetoencephalography. The cortical representations of D 1 and D 2 (somatosensory‐evoked fields) were computed from the ensemble‐averaged data using (a) dipole model fits and (b) singular value decomposition. Individual adjacent/primary response ratios were measured, and group response ratio data were fitted with straight lines. Local overconnectivity in autism implies steeper ASD vs. NT group slopes. Our findings did not support local overconnectivity. Slopes were found to be significantly shallower for the ASD group than the NT group. Our findings support the idea of local underconnectivity in the somatosensory cortex of the brains of individuals with ASD. Autism Res 2013, 6: 190–200. © 2013 International Society for Autism Research, Wiley Periodicals, Inc.

Auteur·ices de l’étude dans cette référence citée

Ouvrir le DOI Lien vers la source citée
Publication avec DOI Récupéré Publication crossref

Michael A. Grubb, Marlene Behrmann, Ryan Egan, Nancy J. Minshew, Marisa Carrasco, David J. Heeger (2013). Endogenous Spatial Attention: Evidence for Intact Functioning in Adults With Autism. Autism Research, 6(2), 108-118. Wiley.

Date de publication
20/02/2013
Identifiant
10.1002/aur.1269
Auteurs
Michael A. Grubb, Marlene Behrmann, Ryan Egan, Nancy J. Minshew, Marisa Carrasco, David J. Heeger
Source
Autism Research
Détails
6(2), 108-118
Type de référence
article
Éditeur
Wiley
Source de métadonnées
crossref

Résumé

Rapid manipulation of the attention field (i.e. the location and spread of visual spatial attention) is a critical aspect of human cognition, and previous research on spatial attention in individuals with autism spectrum disorders (ASD ) has produced inconsistent results. In a series of three psychophysical experiments, we evaluated claims in the literature that individuals with ASD exhibit a deficit in voluntarily controlling the deployment and size of the spatial attention field. We measured the spatial distribution of performance accuracies and reaction times to quantify the sizes and locations of the attention field, with and without spatial uncertainty (i.e. the lack of predictability concerning the spatial position of the upcoming stimulus). We found that high‐functioning adults with autism exhibited slower reaction times overall with spatial uncertainty, but the effects of attention on performance accuracies and reaction times were indistinguishable between individuals with autism and typically developing individuals in all three experiments. These results provide evidence of intact endogenous spatial attention function in high‐functioning adults with ASD, suggesting that atypical endogenous attention cannot be a latent characteristic of autism in general. Autism Res 2013, 6: 108–118. © 2013 International Society for Autism Research, Wiley Periodicals, Inc.

Auteur·ices de l’étude dans cette référence citée

Ouvrir le DOI Lien vers la source citée