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Jason L. He, Ericka Wodka, Mark Tommerdahl, Richard A. E. Edden, Mark Mikkelsen, Stewart H. Mostofsky, Nicolaas A. J. Puts (2021). Disorder-specific alterations of tactile sensitivity in neurodevelopmental disorders. Communications Biology, 4(1), 97. Springer Science and Business Media LLC.

Date de publication
22/01/2021
Identifiant
10.1038/s42003-020-01592-y
Auteurs
Jason L. He, Ericka Wodka, Mark Tommerdahl, Richard A. E. Edden, Mark Mikkelsen, Stewart H. Mostofsky, Nicolaas A. J. Puts
Source
Communications Biology
Détails
4(1), 97
Type de référence
article
Éditeur
Springer Science and Business Media LLC
Source de métadonnées
crossref

Résumé

Abstract Alterations of tactile processing have long been identified in autism spectrum disorders (ASD) and attention-deficit/hyperactivity disorder (ADHD). However, the extent to which these alterations are disorder-specific, rather than disorder-general, and how they relate to the core symptoms of each disorder, remains unclear. We measured and compared tactile detection, discrimination, and order judgment thresholds between a large sample of children with ASD, ADHD, ASD + ADHD combined and typically developing controls. The pattern of results suggested that while difficulties with tactile detection and order judgement were more common in children with ADHD, difficulties with tactile discrimination were more common in children with ASD. Interestingly, in our subsequent correlation analyses between tactile perception and disorder-specific clinical symptoms, tactile detection and order judgment correlated exclusively with the core symptoms of ADHD, while tactile discrimination correlated exclusively with the symptoms of ASD. When taken together, these results suggest that disorder-specific alterations of lower-level sensory processes exist and are specifically related to higher-level clinical symptoms of each disorder.

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