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Post published on Twitter/X on 22 Jan 2021 11:32

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Jason L. He, Ericka Wodka, Mark Tommerdahl, Richard A. E. Edden, Mark Mikkelsen, Stewart H. Mostofsky, Nicolaas A. J. Puts (2021). Disorder-specific alterations of tactile sensitivity in neurodevelopmental disorders. Communications Biology, 4(1), 97. Springer Science and Business Media LLC.

Publication date
22 Jan 2021
Identifier
10.1038/s42003-020-01592-y
Authors
Jason L. He, Ericka Wodka, Mark Tommerdahl, Richard A. E. Edden, Mark Mikkelsen, Stewart H. Mostofsky, Nicolaas A. J. Puts
Source
Communications Biology
Details
4(1), 97
Reference type
article
Publisher
Springer Science and Business Media LLC
Metadata source
crossref

Abstract

Abstract Alterations of tactile processing have long been identified in autism spectrum disorders (ASD) and attention-deficit/hyperactivity disorder (ADHD). However, the extent to which these alterations are disorder-specific, rather than disorder-general, and how they relate to the core symptoms of each disorder, remains unclear. We measured and compared tactile detection, discrimination, and order judgment thresholds between a large sample of children with ASD, ADHD, ASD + ADHD combined and typically developing controls. The pattern of results suggested that while difficulties with tactile detection and order judgement were more common in children with ADHD, difficulties with tactile discrimination were more common in children with ASD. Interestingly, in our subsequent correlation analyses between tactile perception and disorder-specific clinical symptoms, tactile detection and order judgment correlated exclusively with the core symptoms of ADHD, while tactile discrimination correlated exclusively with the symptoms of ASD. When taken together, these results suggest that disorder-specific alterations of lower-level sensory processes exist and are specifically related to higher-level clinical symptoms of each disorder.

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