Publication avec DOI
Récupéré
Publication
crossref
Lonnie Zwaigenbaum, Susan E Bryson, Jessica Brian, Isabel M Smith, Lori Sacrey, Vickie Armstrong, Wendy Roberts, Peter Szatmari, et al.
(2021).
Assessment of Autism Symptoms From 6 to 18 Months of Age Using the Autism Observation Scale for Infants in a Prospective High-Risk Cohort.
Child Development, 92(3), 1187-1198.
Oxford University Press (OUP).
- Date de publication
-
31/05/2021
- Identifiant
-
10.1111/cdev.13485
- Auteurs
-
Lonnie Zwaigenbaum,
Susan E Bryson,
Jessica Brian,
Isabel M Smith,
Lori Sacrey,
Vickie Armstrong,
Wendy Roberts,
Peter Szatmari,
Nancy Garon,
Tracy Vaillancourt,
Caroline Roncadin
- Source
- Child Development
- Détails
- 92(3), 1187-1198
- Type de référence
- article
- Éditeur
- Oxford University Press (OUP)
- Source de métadonnées
- crossref
Résumé
Abstract The objectives were to characterize behavioral signs of autism spectrum disorder (ASD) in younger siblings of diagnosed children (high-risk; HR) and examine classification features of the Autism Observation Scale for Infants (AOSI). Participants (501 HR and 180 low-risk [LR]) were assessed between 6 and 18 months using the AOSI and at age 3 for ASD diagnoses. Total AOSI scores differentiated HR infants later diagnosed with ASD starting at 12 months. ROC analyses identified 12- and 18-month cutoff scores associated with 0.52 sensitivity and 0.74 specificity and 0.73 sensitivity and 0.65 specificity, respectively. Although classification accuracy does not support use as a standalone screen, the AOSI identifies features associated with ASD starting at 6 months and differentiates HR infants with ASD by 12 months.
Auteur·ices de l’étude dans cette référence citée