Reductions in Depression and Anxiety Among Autistic Adults Participating in an Intervention to Promote Healthy Relationships

Graham Holmes, L., Goebel, R., Hollingue, C., Zhu, S., Zhang, H., Shan, W., Wang, S., Caplan, R., Sanchez, A., Wharmby, P., Chiang, M., Person, M., & Rothman, E. F. (2023). Reductions in Depression and Anxiety Among Autistic Adults Participating in an Intervention to Promote Healthy Relationships. The American Journal of Occupational Therapy, 77(2). https://doi.org/10.5014/ajot.2023.050108

Publication date: 1 Mar 2023 Added to AutiHub: 5 Jul 2026 Type: Article Article language: English

This publication is integrated into AutiHub through:

Authors

Publication authors
13
Publication authors identified as autistic
1 / 13 (7.7%)

Abstract

IMPORTANCE: Some autistic adults experience depression and anxiety related to their social relationships. There is a need for evidence-based occupational therapy interventions that decrease depression and anxiety and improve the health of social relationships for autistic adults. OBJECTIVE: To determine the feasibility and preliminary effectiveness of the Healthy Relationships on the Autism Spectrum (HEARTS) intervention, a six-session, group-based psychoeducational intervention for the improvement of relationship health. DESIGN: One-group pretest-posttest design with a 3-mo follow-up after baseline. SETTING: United States; online intervention through community organization. PARTICIPANTS: Fifty-five adults, ages 20 to 43 yr, with a professional or self-diagnosis of autism and the capacity to independently participate in an online, group-based, participatory class. INTERVENTION: Participants received 6 90-min weekly sessions that addressed healthy relationship topics, including recognizing abuse, meeting people, maintaining relationships, setting interpersonal boundaries, neurohealth for relationships, and ending relationships. A psychoeducational approach that provided education and involved guided discovery and strategy acquisition was used. OUTCOMES AND MEASURES: All measures were self-administered through an online survey. Depression and anxiety were assessed using instruments from the Patient-Reported Outcomes Measurement Information System. RESULTS: Fifty-five participants completed the intervention. Postintervention scores revealed statistically significant improvements in depression and anxiety. CONCLUSIONS AND RELEVANCE: HEARTS is a promising intervention for improving depression and anxiety among autistic adults and should be investigated further. What This Article Adds: HEARTS offers a potentially effective, nonpharmacological, psychoeducational group-based intervention option to promote healthy relationships for autistic adults. Positionality Statement: This article uses identity-first language (autistic person) in accordance with the preference of autistic self-advocates (Autistic Self Advocacy Network, 2020; Kenny et al., 2016; Lord et al., 2022).

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Bibliography inclusion overview

These indicators describe the cited bibliography imported for this publication. Cited-reference metrics use the cited-reference total as denominator. Cited-author metrics state whether they use all cited-author occurrences or only occurrences linked to authors already integrated in the AutiHub database. They use cached links between cited authors and authors integrated in the AutiHub database. Last computed: 16 Aug 2026 11:30.

Cited references
58
Total cited references integrated for this publication.
Cited references with an identified autistic author
6 / 58 (10.3%)
Cited author occurrences identified as autistic
10 / 338 (3.0%)
Among occurrences linked to AutiHub author records: 10 / 108 (9.3%). Distinct cited authors identified as autistic: 10 / 298 (3.4%).
Cited author occurrences linked to AutiHub author records
108 / 338 (32.0%)
Distinct linked cited authors: 83 / 298 (27.9%)
Linked cited-author occurrences not identified as autistic
98 / 108 (90.7%)
Among linked cited-author occurrences only. Across all cited-author occurrences: 98 / 338 (29.0%). Distinct linked cited authors not identified as autistic: 73 / 83 (88.0%).
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