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Billet publié sur Twitter/X le 04/07/2021 12:56

Twitter/X Essai clinique clinicaltrials.gov Extrait cité dans le billet Question posée par Dawson dans le billet Lien intégré au billet Termes sur l’autisme

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Essai clinique Récupéré Publication clinicaltrials.gov

NORCE Norwegian Research Centre AS, University of Bergen, University of Vienna (2021). Music for Autism (M4A). ClinicalTrials.gov. NORCE Norwegian Research Centre AS.

Date de publication
01/08/2021
Identifiant
NCT04936048
Auteurs
NORCE Norwegian Research Centre AS, University of Bergen, University of Vienna
Source
ClinicalTrials.gov
Type de référence
clinical_trial
Éditeur
NORCE Norwegian Research Centre AS
Source de métadonnées
clinicaltrials.gov

Résumé

The Music for Autism (M4A) trial evaluates the neurobehavioral outcomes of a music therapy (MT) intervention, compared to a matched play therapy (PT) intervention, on social communication skills, brain connectivity and structural brain changes. In a crossover randomised controlled trial (RCT), 80 children with autism across all levels of functioning, aged 6-12 years, undergo a baseline assessment, which includes measurements of social communication, participation, functional connectivity and brain structure. Participants are then randomly allocated to a sequence of interventions (MT-PT or PT-MT) and assessments are taken before and after each intervention period. Both interventions will target common goals and follow the same structure, while at the same time allowing for flexibility in the therapists' approach. It is hypothesized that 12 weeks of intervention through MT, compared to PT, will improve social communication skills, participation, and other relevant mental health outcomes in children with autism spectrum disorder (ASD), as well as regulate resting-state functional over and under-connectivity and increase grey and white matter volume in specified regions. The investigators also expect changes in functional brain connectivity to correlate with behavioural outcome measures, specifically with improved social communication skills.