Billets de Michelle Dawson
Liens cités structurés
Irene Mollinedo-Gajate, Chenchen Song, Marcos Sintes-Rodriguez, Tobias Whelan, Anaïs Soula, Aslihan Selimbeyoglu, Shaun Hurley, Thomas Knöpfel (2020). Psilocybin rescues sociability deficits in an animal model of autism. openRxiv.
Résumé
Abstract Autism spectrum disorder (ASD) is characterized by core deficits in social interaction. The classic serotonergic psychedelic psilocybin has been suggested as a therapeutic agent that may ameliorate in the core symptomology of ASD. We found that the acute response to psilocybin was attenuated in the prenatal valproic acid exposure mouse model of ASD, and importantly, psilocybin rescued the social behavioural abnormalities present in these ASD model mice.
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