Economic Evaluation of anti-epileptic Medicines for Autistic Children with Epilepsy

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Tinelli, M., Roddy, Á., Knapp, M., Arango, C., Méndez, M. A., Cusack, J., Murphy, D., Canitano, R., Oakley, B. F., & Quoidbach, V. (2023). Economic Evaluation of anti-epileptic Medicines for Autistic Children with Epilepsy. Journal of Autism and Developmental Disorders, 54(7), 2733-2741. https://doi.org/10.1007/s10803-023-05941-8

Publication date: 4 May 2023 Added to AutiHub: 5 Jul 2026 Type: Article Article language: English
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Authors

Publication authors
10
Publication authors identified as autistic
1 / 10 (10.0%)
  1. Michela Tinelli
  2. Áine Roddy
  3. Martín Knapp
  4. Celso Arango
  5. María Andreina Méndez
  1. James Cusack *
  2. Declan Murphy
  3. Roberto Canitano
  4. Bethany F. Oakley
  5. Vinciane Quoidbach

Abstract

We examine the cost-effectiveness of treating epilepsy with anti-epileptic medicines in autistic children, looking at impacts on healthcare providers (in England, Ireland, Italy and Spain) and children's families (in Ireland). We find carbamazepine to be the most cost-effective drug to try first in children with newly diagnosed focal seizures. For England and Spain, oxcarbazepine is the most cost-effective treatment when taken as additional treatment for those children whose response to monotherapy is suboptimal. In Ireland and Italy, gabapentin is the most cost-effective option. Our additional scenario analysis presents the aggregate cost to families with autistic children who are being treated for epilepsy: this cost is considerably higher than healthcare provider expenditure.

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Cited references
43
Total cited references integrated for this publication.
Cited references with an identified autistic author
0 / 43 (0.0%)
Cited author occurrences identified as autistic
0 / 175 (0.0%)
Among occurrences linked to AutiHub author records: 0 / 15 (0.0%). Distinct cited authors identified as autistic: 0 / 154 (0.0%).
Cited author occurrences linked to AutiHub author records
15 / 175 (8.6%)
Distinct linked cited authors: 10 / 154 (6.5%)
Linked cited-author occurrences not identified as autistic
15 / 15 (100.0%)
Among linked cited-author occurrences only. Across all cited-author occurrences: 15 / 175 (8.6%). Distinct linked cited authors not identified as autistic: 10 / 10 (100.0%).
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