Economic Evaluation of anti-epileptic Medicines for Autistic Children with Epilepsy

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Tinelli, M., Roddy, Á., Knapp, M., Arango, C., Méndez, M. A., Cusack, J., Murphy, D., Canitano, R., Oakley, B., & Quoidbach, V. (2023). Economic Evaluation of anti-epileptic Medicines for Autistic Children with Epilepsy. Journal of Autism and Developmental Disorders, 54(7), 2733-2741. https://doi.org/10.1007/s10803-023-05941-8

Publication date: 4 May 2023 Added to AutiHub: 5 Jul 2026 Type: Article Article language: English
Publisher source (DOI) Full text OpenAlex source

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Authors

Publication authors
10
Publication authors identified as autistic
1 / 10 (10.0%)
  1. Michela Tinelli
  2. Áine Roddy
  3. Martin Knapp
  4. Celso Arango
  5. María Andreina Méndez
  1. James Cusack *
  2. Declan Murphy
  3. Roberto Canitano
  4. Bethany Oakley
  5. Vinciane Quoidbach

Abstract

We examine the cost-effectiveness of treating epilepsy with anti-epileptic medicines in autistic children, looking at impacts on healthcare providers (in England, Ireland, Italy and Spain) and children's families (in Ireland). We find carbamazepine to be the most cost-effective drug to try first in children with newly diagnosed focal seizures. For England and Spain, oxcarbazepine is the most cost-effective treatment when taken as additional treatment for those children whose response to monotherapy is suboptimal. In Ireland and Italy, gabapentin is the most cost-effective option. Our additional scenario analysis presents the aggregate cost to families with autistic children who are being treated for epilepsy: this cost is considerably higher than healthcare provider expenditure.

Bibliography cited by this reference

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Cited bibliography overview

These indicators describe the bibliography cited by this publication. An author name is counted each time it appears in one cited reference, so the same person can be counted more than once. Names not yet linked to an author already present in AutiHub are treated as unknown, not as non-autistic. Last computed: 2 Oct 2026 01:00.

Cited references
43
With a DOI
35
Without a DOI, from raw bibliography text
8
0 / 43 (0.0%) cited references include at least one author identified as autistic.
References with data to complete
9 / 43 (20.9%)
References with detected author names
34 / 43 (79.1%)
Without detected author names
9
Without a structured title
8
Without a stable identifier
8
References with raw author names still to review
8
References with external metadata lookup issues
0
These indicators apply to cited references displayed on this page, after technical duplicates have been merged. A reference without a DOI can still support author statistics when a title and author names are available.
Author names detected in the cited bibliography
175
From DOI or external metadata
175
From validated raw bibliography text
0
Raw names already validated
0
Raw names still to review
9
16 / 175 (9.1%) names are linked to an author already present in AutiHub. 159 / 175 (90.9%) names are not yet linked.
Names linked to a person identified as autistic
0 / 175 (0.0%)
Calculated across all author names detected in the cited bibliography. Among names linked to an author already present in AutiHub: 0 / 16 (0.0%). Distinct people identified as autistic: 0 / 154 (0.0%).
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