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Post published on Twitter/X on 5 Jul 2021 04:28

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Carolien Torenvliet, Annabeth Groenman, Tulsi Radhoe, Joost Agelink van Rentergem, Wikke van der Putten, Hilde Geurts (2021). Parallel Age-Related Cognitive Effects in Autism: A Cross-Sectional Replication Study. Center for Open Science.

Publication date
2 Jul 2021
Identifier
10.31234/osf.io/47tyc
Authors
Carolien Torenvliet, Annabeth Groenman, Tulsi Radhoe, Joost Agelink van Rentergem, Wikke van der Putten, Hilde Geurts
Reference type
preprint
Publisher
Center for Open Science
Metadata source
crossref

Abstract

Findings on age-related cognitive effects in autism in adulthood are inconsistent across studies. As these studies substantially differ in their methodology, replication studies are needed. In this replication study frequentist (i.e., null-hypothesis significance testing), and Bayesian statistics were used to investigate the hypothesis that in autistic adults compared to non-autistic adults mostly parallel, but also protective age-related cognitive effects can be observed. Participants were 88 autistic adults, and 88 non-autistic matched comparisons (age range: 30-89 years, mean age: 55 years). Cognitive measures were administered on the following six domains: verbal memory, visual memory, working memory, Theory of Mind (ToM), verbal fluency, and processing speed, and self-reported cognitive failures. Non-autistic adults outperformed autistic adults on ToM, verbal fluency, and verbal memory, but only the first two were confirmed with Bayesian replication analyses. Also, more cognitive failures were reported by autistic adults. No interactions between group and age were observed, suggesting a parallel age-related effect on all cognitive domains. In sum, previously observed difficulties in ToM and verbal fluency were replicated which seem to persist at older age. Previously reported parallel age-related cognitive patterns were replicated, yet no evidence for protective age-related patterns was found.

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