Charge nationale et infranationale des troubles mentaux en Chine, 1990-2023 : une analyse systématique de l'étude Global Burden of Disease Study 2023

Titre original en anglais : National and subnational burden of mental disorders in China, 1990–2023: a systematic analysis of the Global Burden of Disease Study 2023

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Li, Y., Zhu, X., Shang, L., Zou, B., Zhang, L., Xu, P., Wang, L., Zhou, M., Santomauro, D., Yin, P., & Wang, G. (2026). National and subnational burden of mental disorders in China, 1990–2023: a systematic analysis of the Global Burden of Disease Study 2023. The Lancet Regional Health - Western Pacific, 73, Article 101936. https://doi.org/10.1016/j.lanwpc.2026.101936

Date de publication: 27/07/2026 Ajout dans AutiHub: 13/10/2026 Type: Article Langue de l’article: Anglais

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Résumé

CONTEXTE : Les troubles mentaux représentent une priorité croissante de santé publique en Chine. Les études existantes se sont largement appuyées sur des itérations de données remplacées et se sont concentrées sur des sous-ensembles de population ou des catégories de maladies spécifiques, laissant une lacune dans la compréhension du paysage épidémiologique complet de la santé mentale dans l'ensemble du pays. Cette étude fournit l'évaluation la plus récente et la plus complète de la charge des troubles mentaux en Chine et dans ses provinces, en utilisant les dernières estimations de la Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2023. METHODES : Conformément à la méthodologie de GBD 2023, nous avons systématiquement analysé les données épidémiologiques et démographiques afin d'évaluer la prévalence, les années de vie ajustées sur l'incapacité (DALY), le taux de prévalence standardisé selon l'âge (ASPR) et le taux de DALY standardisé selon l'âge (ASDR) pour les troubles mentaux et dix sous-types en Chine et dans ses 33 unités administratives de niveau provincial de 1990 à 2023. RESULTATS : En 2023, l'ASPR estimé des troubles mentaux en Chine était de 12 706 (intervalle d'incertitude à 95 % : 11 438, 14 573) pour 100 000 habitants, reflétant une augmentation de 14,6 % (3,5, 30,7) depuis 1990. L'ASDR a atteint 1718 (1272, 2307) pour 100 000 habitants, augmentant de 18,4 % (5,3, 36,9) au cours des trois dernières décennies. Les troubles dépressifs et anxieux sont restés les principaux contributeurs, représentant respectivement 35,6 % et 26,3 % de l'ensemble des DALY attribuables aux troubles mentaux. En outre, les troubles des conduites alimentaires ont présenté la plus forte augmentation de l'ASPR (63,4 % [58,2, 68,2]). Des variations infranationales importantes ont été observées, avec les ASPR les plus élevés à Hong Kong, Gansu, Macao et Shandong, et les plus fortes augmentations en pourcentage à Macao, Hubei, Hong Kong, Xizang et Ningxia. Les femmes présentaient un ASPR plus élevé pour les troubles dépressifs, tandis que les hommes supportaient une charge plus lourde de troubles du spectre de l'autisme, de trouble du déficit de l'attention avec hyperactivité et de trouble des conduites. Tout au long de la vie, la charge de DALY était relativement plus élevée dans les groupes d'âge de 5-19 ans, 30-39 ans et 50-59 ans. INTERPRETATION : La Chine a connu une escalade substantielle de la charge des troubles mentaux au cours des trois dernières décennies. Ce paysage épidémiologique complexe, caractérisé par des vulnérabilités régionales, sexuelles et spécifiques à l'âge distinctes, souligne la nécessité d'un équilibrage structurel et d'interventions ciblées tout au long de la vie. Ces estimations actualisées fournissent une base de données probantes précieuse aux décideurs afin d'optimiser davantage l'allocation des ressources et de mettre en oeuvre des interventions adaptées tout au long de la vie dans le cadre de « Healthy China 2030 ». FINANCEMENT : Sci-Tech Innovation 2030-Major Project of Brain Science and Brain-Inspired Intelligence Technology (no 2021ZD0200600) ; 2025 China Association for Science and Technology (CAST) Young Science and Technology Talents Cultivation Project-Special Program for Doctoral Students.

BACKGROUND: Mental disorders represent a growing public health priority in China. Existing studies have largely relied on superseded data iterations and focused on specific population subsets or disease categories, leaving a gap in understanding the full epidemiological landscape of mental health across the country. This study provides the most up-to-date and comprehensive assessment of the burden of mental disorders in China and its provinces, utilizing the latest estimates from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2023. METHODS: Following the GBD 2023 methodology, we systematically analyzed epidemiological and demographic data to assess the prevalence, disability-adjusted life year (DALY), age-standardized prevalence rate (ASPR) and age-standardized DALY rate (ASDR) for mental disorders and ten subtypes in China and its 33 provincial-level administrative units from 1990 to 2023. FINDINGS: In 2023, the estimated ASPR of mental disorders in China was 12,706 (95% uncertainty interval: 11,438, 14,573) per 100,000 population, reflecting a 14.6% (3.5, 30.7) increase since 1990. The ASDR reached 1718 (1272, 2307) per 100,000, rising by 18.4% (5.3, 36.9) over the past three decades. Depressive and anxiety disorders remained the dominant contributors, accounting for 35.6% and 26.3% of overall DALYs attributable to mental disorders, respectively. Furthermore, eating disorders exhibited the largest growth in ASPR (63.4% [58.2, 68.2]). Substantial subnational variations were observed, with the highest ASPRs in Hong Kong, Gansu, Macao, and Shandong, and the largest percentage increases in Macao, Hubei, Hong Kong, Xizang, and Ningxia. Females experienced a higher ASPR from depressive disorders, while males bore a heavier burden of autism spectrum disorders, attention-deficit/hyperactivity disorder, and conduct disorder. Across the lifespan, the burden of DALYs was relatively higher in the 5-19, 30-39, and 50-59 age groups. INTERPRETATION: China has witnessed a substantial escalation in the burden of mental disorders over the past three decades. This complex epidemiological landscape, characterized by distinct regional, sex, and age-specific vulnerabilities, underscores the necessity for structural balancing and targeted life-course interventions. These up-to-date estimates provide a valuable evidence base for policymakers to further optimize resource allocation and implement tailored life-course interventions within the "Healthy China 2030" framework. FUNDING: Sci-Tech Innovation 2030-Major Project of Brain Science and Brain-Inspired Intelligence Technology (No. 2021ZD0200600); 2025 China Association for Science and Technology (CAST) Young Science and Technology Talents Cultivation Project-Special Program for Doctoral Students.

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78
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Sans identifiant stable
22
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9222
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631 / 9222 (6,8 %) noms sont associés à un·e auteurice déjà présent·e dans AutiHub. 8591 / 9222 (93,2 %) noms ne sont pas encore associés.
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Calculé sur l’ensemble des noms d’auteurices détectés dans la bibliographie citée. Parmi les noms associés à un·e auteurice déjà présent·e dans AutiHub : 4 / 631 (0,6 %). Personnes distinctes identifiées comme autistes : 1 / 4237 (0,0 %).
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