Prolifération dendritique excessive et signalisation ERK élevée au cours du développement néonatal dans un modèle murin d'autisme

Titre original en anglais : Dendritic overgrowth and elevated ERK signaling during neonatal development in a mouse model of autism

Cette publication est incluse dans le projet « Contributions académiques de personnes autistes sur l’autisme ». un auteur·ice de cette publication est identifié·e comme autiste dans le projet.

À propos de la mention auteur·ice autiste

Sources de métadonnées utilisées pour cette référence

OpenAlex Crossref OpenCitations
En savoir plus sur les sources utilisées

Cheng, N., Alshammari, F., Hughes, E., Khanbabaei, M., & Rho, J. M. (2017). Dendritic overgrowth and elevated ERK signaling during neonatal development in a mouse model of autism. PLOS ONE, 12(6), e0179409. https://doi.org/10.1371/journal.pone.0179409

Date de publication: 13/06/2017 Ajout dans AutiHub: 29/08/2026 Type: Article Langue de l’article: Anglais
Source éditeur (DOI) Texte intégral Source OpenAlex

Cette publication est intégrée dans AutiHub via :

Auteurs

Auteur·ices des publications
5
Auteur·ices de la publication identifié·es comme autistes
1 / 5 (20,0 %)
  1. Ning Cheng
  2. Fawaz Alshammari
  3. Elizabeth Hughes *
  4. Maryam Khanbabaei
  5. Jong M. Rho

Résumé

Le trouble du spectre de l'autisme (ci-après désigné par « ASD ») est une affection neurodéveloppementale hétérogène caractérisée par une altération de la communication et des interactions sociales, ainsi que par des activités ou intérêts restreints et répétitifs. Des altérations de la connectivité des réseaux et de la fonction mnésique sont fréquemment observées chez les patients autistes, impliquant souvent l'hippocampe. Cependant, les changements spécifiques au cours du développement cérébral précoce conduisant à un fonctionnement perturbé restent largement inconnus. Nous avons ici étudié le développement de l'arborisation dendritique des neurones pyramidaux CA1 de l'hippocampe dans le modèle murin d'autisme BTBR T+tf/J (BTBR). Les souris BTBR présentent les caractéristiques comportementales définissant l'autisme et montrent également des troubles de l'apprentissage et de la mémoire. Nous avons constaté que, par rapport aux animaux témoins C57BL/6J (B6), les longueurs des dendrites apicales et basales étaient significativement plus grandes chez les animaux BTBR nouveau-nés. De plus, les dendrites basales des souris BTBR présentaient une complexité de ramifications plus élevée. En revanche, l'aire de la section transversale du soma était inchangée. En outre, nous avons observé une densité similaire de neurones pyramidaux CA1 et une épaisseur similaire de la couche neuronale entre les deux souches. Ainsi, il existait une prolifération excessive spécifique et compartimentalisée des dendrites au cours du développement précoce chez les animaux BTBR. L'analyse biochimique a en outre montré que la voie des kinases régulées par les signaux extracellulaires (ERK) était régulée à la hausse dans l'hippocampe des animaux BTBR nouveau-nés. Étant donné que la structure dendritique est essentielle à l'intégration et à la transmission de l'information, nos données suggèrent qu'une altération du développement des dendrites pourrait potentiellement contribuer à la fonction hippocampique et au comportement altérés observés dans le modèle BTBR, et que cela pourrait être lié à une activation accrue de la voie ERK.

Autism spectrum disorder (hereafter referred to as "ASD") is a heterogeneous neurodevelopmental condition characterized by impaired social communication and interactions, and restricted, repetitive activities or interests. Alterations in network connectivity and memory function are frequently observed in autism patients, often involving the hippocampus. However, specific changes during early brain development leading to disrupted functioning remain largely unclear. Here, we investigated the development of dendritic arbor of hippocampal CA1 pyramidal neurons in the BTBR T+tf/J (BTBR) mouse model of autism. BTBR mice display the defining behavioural features of autism, and also exhibit impaired learning and memory. We found that compared to control C57BL/6J (B6) animals, the lengths of both apical and basal dendrites were significantly greater in neonatal BTBR animals. Further, basal dendrites in the BTBR mice had higher branching complexity. In contrast, cross-sectional area of the soma was unchanged. In addition, we observed a similar density of CA1 pyramidal neurons and thickness of the neuronal layer between the two strains. Thus, there was a specific, compartmentalized overgrowth of dendrites during early development in the BTBR animals. Biochemical analysis further showed that the extracellular signal-regulated kinases (ERK) pathway was up-regulated in the hippocampus of neonatal BTBR animals. Since dendritic structure is critical for information integration and relay, our data suggest that altered development of dendrites could potentially contribute to impaired hippocampal function and behavior observed in the BTBR model, and that this might be related to increased activation of the ERK pathway.

Bibliographie citée par cette référence

Les références citées sont importées depuis des sources externes de métadonnées lorsqu’elles sont disponibles. La liste peut être partielle.

Vue d’ensemble de la bibliographie citée

Ces indicateurs décrivent la bibliographie citée par cette publication. Un nom d’auteurice est compté chaque fois qu’il apparaît dans une référence citée : une même personne peut donc être comptée plusieurs fois. Les noms qui ne sont pas encore associés à un·e auteurice déjà présent·e dans AutiHub sont traités comme inconnus, pas comme non autistes. Dernier calcul : 12/09/2026 17:55.

Références citées
105
Avec un DOI
104
Sans DOI, à partir du texte brut de la bibliographie
1
4 / 105 (3,8 %) références citées comprennent au moins une personne identifiée comme autiste.
Références avec données à compléter
2 / 105 (1,9 %)
Références avec noms d’auteurices détectés
103 / 105 (98,1 %)
Sans nom d’auteurice détecté
2
Sans titre structuré
1
Sans identifiant stable
1
Références avec noms bruts d’auteurices restant à vérifier
1
Références avec problème de récupération des métadonnées externes
0
Ces indicateurs portent sur les références citées affichées sur cette page, après fusion des doublons techniques. Une référence sans DOI peut quand même soutenir les statistiques d’auteurices lorsqu’un titre et des noms d’auteurices sont disponibles.
Noms d’auteurices détectés dans la bibliographie citée
692
À partir du DOI ou de métadonnées externes
692
À partir du texte brut validé de la bibliographie
0
Noms bruts déjà validés
0
Noms bruts restant à vérifier
2
59 / 692 (8,5 %) noms sont associés à un·e auteurice déjà présent·e dans AutiHub. 633 / 692 (91,5 %) noms ne sont pas encore associés.
Noms associés à une personne identifiée comme autiste
4 / 692 (0,6 %)
Calculé sur l’ensemble des noms d’auteurices détectés dans la bibliographie citée. Parmi les noms associés à un·e auteurice déjà présent·e dans AutiHub : 4 / 59 (6,8 %). Personnes distinctes identifiées comme autistes : 2 / 618 (0,3 %).
  1. (2006). The Hippocampus Book . Oxford University Press.
    Type: Livre DOI: 10.1093/acprof:oso/9780195100273.001.0001 OpenAlex: https://openalex.org/W644076287
    OpenAlex
  2. Emanuel DiCicco-Bloom , Catherine Lord , Lonnie Zwaigenbaum , Eric Courchesne , Stephen R. Dager , Christoph Schmitz et al. (2006). The Developmental Neurobiology of Autism Spectrum Disorder . The Journal of Neuroscience, 26(26), 6897-6906. Society for Neuroscience.
    Type: Article DOI: 10.1523/jneurosci.1712-06.2006 OpenAlex: https://openalex.org/W2168013774
    Crossref OpenAlex OpenCitations
  3. Beth Crowell , Gum Hwa Lee , Ina Nikolaeva , Valentina Dal Pozzo , Gabriella D’Arcangelo (2015). Complex Neurological Phenotype in Mutant Mice Lacking Tsc2 in Excitatory Neurons of the Developing Forebrain . eneuro, 2(6), ENEURO.0046-15.2015. Society for Neuroscience.
    Type: Article DOI: 10.1523/eneuro.0046-15.2015 OpenAlex: https://openalex.org/W2221887544
    Crossref OpenAlex OpenCitations
  4. Jacob Ellegood , Jacqueline N. Crawley (2015). Behavioral and Neuroanatomical Phenotypes in Mouse Models of Autism . Neurotherapeutics, 12(3), 521-533. Elsevier BV.
    Type: Article DOI: 10.1007/s13311-015-0360-z OpenAlex: https://openalex.org/W1917519329
    Crossref OpenAlex OpenCitations
  5. Daniel H. Geschwind (2009). Advances in Autism . Annual Review of Medicine, 60(1), 367-380. Annual Reviews.
    Type: Article DOI: 10.1146/annurev.med.60.053107.121225 OpenAlex: https://openalex.org/W2145055578
    Crossref OpenAlex OpenCitations
  6. Daniela M Cochoy , Alexander Kolevzon , Yuji Kajiwara , Michael Schoen , Maria Pascual-Lucas , Stacey Lurie et al. (2015). Phenotypic and functional analysis of SHANK3 stop mutations identified in individuals with ASD and/or ID . Molecular Autism, 6(1), 23. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1186/s13229-015-0020-5 OpenAlex: https://openalex.org/W2009852285
    Crossref OpenAlex OpenCitations
  7. Svitlana Shpyleva , Samuil Ivanovsky , Aline de Conti , Stepan Melnyk , Volodymyr Tryndyak , Frederick A. Beland et al. (2014). Cerebellar Oxidative DNA Damage and Altered DNA Methylation in the BTBR T+tf/J Mouse Model of Autism and Similarities with Human Post Mortem Cerebellum . PLoS ONE, 9(11), e113712. Public Library of Science (PLoS).
    Type: Article DOI: 10.1371/journal.pone.0113712 OpenAlex: https://openalex.org/W1964262871
    Crossref OpenAlex OpenCitations
  8. Meng-Chuan Lai , Michael Lombardo , Simon Baron-Cohen (2014). Autism . The Lancet, 383(9920), 896-910. Elsevier BV.
    Type: Article DOI: 10.1016/s0140-6736(13)61539-1 OpenAlex: https://openalex.org/W4210708461
    Crossref OpenAlex OpenCitations
  9. Regina Waltes , Johannes Gfesser , Denise Haslinger , Katja Schneider-Momm , Monica Biscaldi , Anette Voran et al. (2014). Common EIF4E variants modulate risk for autism spectrum disorders in the high-functioning range . Journal of Neural Transmission, 121(9), 1107-1116. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1007/s00702-014-1230-2 OpenAlex: https://openalex.org/W2060241033
    Crossref OpenAlex OpenCitations
  10. Nelson Spruston (2008). Pyramidal neurons: dendritic structure and synaptic integration . Nature Reviews Neuroscience, 9(3), 206-221. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1038/nrn2286 OpenAlex: https://openalex.org/W1967324141
    Crossref OpenAlex OpenCitations
  11. Danielle C. Llaneza , Susan V. DeLuke , Myra Batista , Jacqueline N. Crawley , Kristin V. Christodulu , Cheryl A. Frye (2010). Communication, interventions, and scientific advances in autism: A commentary . Physiology & Behavior, 100(3), 268-276. Elsevier BV.
    Type: Article DOI: 10.1016/j.physbeh.2010.01.003 OpenAlex: https://openalex.org/W2031506439
    Crossref OpenAlex OpenCitations
  12. Eric Courchesne , Peter R. Mouton , Michael E. Calhoun , Katerina Semendeferi , Clelia Ahrens-Barbeau , Melodie J. Hallet et al. (2011). Neuron Number and Size in Prefrontal Cortex of Children With Autism . JAMA, 306(18), 2001. American Medical Association (AMA).
    Type: Article DOI: 10.1001/jama.2011.1638 OpenAlex: https://openalex.org/W2124712820
    Crossref OpenAlex OpenCitations
  13. M.L. Scattoni , A. Martire , G. Cartocci , A. Ferrante , L. Ricceri (2013). Reduced social interaction, behavioural flexibility and BDNF signalling in the BTBR T+tf/J strain, a mouse model of autism . Behavioural Brain Research, 251, 35-40. Elsevier BV.
    Type: Article DOI: 10.1016/j.bbr.2012.12.028 OpenAlex: https://openalex.org/W1973412307
    Crossref OpenAlex OpenCitations
  14. E. H. Aylward , N. J. Minshew , K. Field , B. F. Sparks , N. Singh (2002). Effects of age on brain volume and head circumference in autism . Neurology, 59(2), 175-183. Ovid Technologies (Wolters Kluwer Health).
    Type: Article DOI: 10.1212/wnl.59.2.175 OpenAlex: https://openalex.org/W2126819661
    Crossref OpenAlex OpenCitations
  15. Adrian L. Oblak , Douglas L. Rosene , Thomas L. Kemper , Margaret Bauman , Gene J. Blatt (2011). Altered posterior cingulate cortical cyctoarchitecture, but normal density of neurons and interneurons in the posterior cingulate cortex and fusiform gyrus in autism . Autism Research, 4(3), 200-211. Wiley.
    Type: Article DOI: 10.1002/aur.188 OpenAlex: https://openalex.org/W2010165945
    Crossref OpenAlex OpenCitations
  16. Urit Gordon , Alon Polsky , Jackie Schiller (2006). Plasticity Compartments in Basal Dendrites of Neocortical Pyramidal Neurons . The Journal of Neuroscience, 26(49), 12717-12726. Society for Neuroscience.
    Type: Article DOI: 10.1523/jneurosci.3502-06.2006 OpenAlex: https://openalex.org/W1974719053
    Crossref OpenAlex OpenCitations
  17. E. Courchesne , C. M. Karns , H. R. Davis , R. Ziccardi , R. A. Carper , Z. D. Tigue et al. (2001). Unusual brain growth patterns in early life in patients with autistic disorder . Neurology, 57(2), 245-254. Ovid Technologies (Wolters Kluwer Health).
    Type: Article DOI: 10.1212/wnl.57.2.245 OpenAlex: https://openalex.org/W2025551837
    Crossref OpenAlex OpenCitations
  18. Akira Yoshii , Martha Constantine‐Paton (2010). Postsynaptic BDNF‐TrkB signaling in synapse maturation, plasticity, and disease . Developmental Neurobiology, 70(5), 304-322. Wiley.
    Type: Article DOI: 10.1002/dneu.20765
    Crossref OpenCitations
  19. Wei-Qun Fang , Wei-Wei Chen , Liwen Jiang , Kai Liu , Wing-Ho Yung , Amy K.Y. Fu et al. (2014). Overproduction of Upper-Layer Neurons in the Neocortex Leads to Autism-like Features in Mice . Cell Reports, 9(5), 1635-1643. Elsevier BV.
    Type: Article DOI: 10.1016/j.celrep.2014.11.003 OpenAlex: https://openalex.org/W1984458710
    Crossref OpenAlex OpenCitations
  20. B. F. Sparks , S. D. Friedman , D. W. Shaw , E. H. Aylward , D. Echelard , A. A. Artru et al. (2002). Brain structural abnormalities in young children with autism spectrum disorder . Neurology, 59(2), 184-192. Ovid Technologies (Wolters Kluwer Health).
    Type: Article DOI: 10.1212/wnl.59.2.184 OpenAlex: https://openalex.org/W2000619876
    Crossref OpenAlex OpenCitations
  21. Terence P. Herbert , Andrew R. Tee , Christopher G. Proud (2002). The Extracellular Signal-regulated Kinase Pathway Regulates the Phosphorylation of 4E-BP1 at Multiple Sites . Journal of Biological Chemistry, 277(13), 11591-11596. Elsevier BV.
    Type: Article DOI: 10.1074/jbc.m110367200 OpenAlex: https://openalex.org/W1986235662
    Crossref OpenAlex OpenCitations
  22. Heather Cody Hazlett , Michele Poe , Guido Gerig , Rachel Gimpel Smith , James Provenzale , Allison Ross et al. (2005). Magnetic Resonance Imaging and Head Circumference Study of Brain Size in Autism . Archives of General Psychiatry, 62(12), 1366. American Medical Association (AMA).
    Type: Article DOI: 10.1001/archpsyc.62.12.1366 OpenAlex: https://openalex.org/W2170599555
    Crossref OpenAlex OpenCitations
  23. Diane T Stephenson , Sharon M O'Neill , Sapna Narayan , Aadhya Tiwari , Elizabeth Arnold , Harry D Samaroo et al. (2011). Histopathologic characterization of the BTBR mouse model of autistic-like behavior reveals selective changes in neurodevelopmental proteins and adult hippocampal neurogenesis . Molecular Autism, 2(1), 7. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1186/2040-2392-2-7 OpenAlex: https://openalex.org/W2029887906
    Crossref OpenAlex OpenCitations
  24. Wanda M. Snow , Kelly Hartle , Tammy L. Ivanco (2008). Altered morphology of motor cortex neurons in the VPA rat model of autism . Developmental Psychobiology, 50(7), 633-639. Wiley.
    Type: Article DOI: 10.1002/dev.20337 OpenAlex: https://openalex.org/W1987778037
    Crossref OpenAlex OpenCitations
  25. Cynthia M. Schumann , Cinnamon S. Bloss , Cynthia Carter Barnes , Graham M. Wideman , Ruth A. Carper , Natacha Akshoomoff et al. (2010). Longitudinal Magnetic Resonance Imaging Study of Cortical Development through Early Childhood in Autism . The Journal of Neuroscience, 30(12), 4419-4427. Society for Neuroscience.
    Type: Article DOI: 10.1523/jneurosci.5714-09.2010 OpenAlex: https://openalex.org/W2039929057
    Crossref OpenAlex OpenCitations
  26. A.Kimberley McAllister , Donald C. Lo , Lawrence C. Katz (1995). Neurotrophins regulate dendritic growth in developing visual cortex . Neuron, 15(4), 791-803. Elsevier BV.
    Type: Article DOI: 10.1016/0896-6273(95)90171-x OpenAlex: https://openalex.org/W1989053030
    Crossref OpenAlex OpenCitations
  27. Francesco Sforazzini , Alice Bertero , Luca Dodero , Gergely David , Alberto Galbusera , Maria Luisa Scattoni et al. (2016). Altered functional connectivity networks in acallosal and socially impaired BTBR mice . Brain Structure and Function, 221(2), 941-954. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1007/s00429-014-0948-9 OpenAlex: https://openalex.org/W1996471207
    Crossref OpenAlex OpenCitations
  28. Elizabeth Redcay , Eric Courchesne (2005). When Is the Brain Enlarged in Autism? A Meta-Analysis of All Brain Size Reports . Biological Psychiatry, 58(1), 1-9. Elsevier BV.
    Type: Article DOI: 10.1016/j.biopsych.2005.03.026 OpenAlex: https://openalex.org/W2010246526
    Crossref OpenAlex OpenCitations
  29. Jens P. Weber , Bertalan K. Andrásfalvy , Marina Polito , Ádám Magó , Balázs B. Ujfalussy , Judit K. Makara (2016). Location-dependent synaptic plasticity rules by dendritic spine cooperativity . Nature Communications, 7(1), 11380. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1038/ncomms11380 OpenAlex: https://openalex.org/W2335913578
    Crossref OpenAlex OpenCitations
  30. SUZANNE GOH , BRADLEY S PETERSON (2012). Imaging evidence for disturbances in multiple learning and memory systems in persons with autism spectrum disorders . Developmental Medicine & Child Neurology, 54(3), 208-213. Wiley.
    Type: Article DOI: 10.1111/j.1469-8749.2011.04153.x OpenAlex: https://openalex.org/W1996752247
    Crossref OpenAlex OpenCitations
  31. Lucina Q. Uddin , Kaustubh Supekar , Vinod Menon (2013). Reconceptualizing functional brain connectivity in autism from a developmental perspective . Frontiers in Human Neuroscience, 7, 458. Frontiers Media SA.
    Type: Article DOI: 10.3389/fnhum.2013.00458 OpenAlex: https://openalex.org/W2042981671
    Crossref OpenAlex OpenCitations
  32. Philippe P. Roux , David Shahbazian , Hieu Vu , Marina K. Holz , Michael S. Cohen , Jack Taunton et al. (2007). RAS/ERK Signaling Promotes Site-specific Ribosomal Protein S6 Phosphorylation via RSK and Stimulates Cap-dependent Translation . Journal of Biological Chemistry, 282(19), 14056-14064. Elsevier BV.
    Type: Article DOI: 10.1074/jbc.m700906200 OpenAlex: https://openalex.org/W1998682097
    Crossref OpenAlex OpenCitations
  33. Jose O. Maximo , Elyse J. Cadena , Rajesh K. Kana (2014). The Implications of Brain Connectivity in the Neuropsychology of Autism . Neuropsychology Review, 24(1), 16-31. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1007/s11065-014-9250-0 OpenAlex: https://openalex.org/W2023044037
    Crossref OpenAlex OpenCitations
  34. Dionisio A. Amodeo , Joshua H. Jones , John A. Sweeney , Michael E. Ragozzino (2012). Differences in BTBR T+ tf/J and C57BL/6J mice on probabilistic reversal learning and stereotyped behaviors . Behavioural Brain Research, 227(1), 64-72. Elsevier BV.
    Type: Article DOI: 10.1016/j.bbr.2011.10.032 OpenAlex: https://openalex.org/W2033844955
    Crossref OpenAlex OpenCitations
  35. Michael Häusser , Nelson Spruston , Greg J. Stuart (2000). Diversity and Dynamics of Dendritic Signaling . Science, 290(5492), 739-744. American Association for the Advancement of Science (AAAS).
    Type: Article DOI: 10.1126/science.290.5492.739 OpenAlex: https://openalex.org/W2133258871
    Crossref OpenAlex OpenCitations
  36. Niklas Krumm , Brian J. O’Roak , Jay Shendure , Evan E. Eichler (2014). A de novo convergence of autism genetics and molecular neuroscience . Trends in Neurosciences, 37(2), 95-105. Elsevier BV.
    Type: Article DOI: 10.1016/j.tins.2013.11.005 OpenAlex: https://openalex.org/W2064332273
    Crossref OpenAlex OpenCitations
  37. Ivy S. Samuels , Sulagna C. Saitta , Gary E. Landreth (2009). MAP'ing CNS Development and Cognition: An ERKsome Process . Neuron, 61(2), 160-167. Elsevier BV.
    Type: Article DOI: 10.1016/j.neuron.2009.01.001 OpenAlex: https://openalex.org/W2001324348
    Crossref OpenAlex OpenCitations
  38. Yuh-Nung Jan , Lily Yeh Jan (2010). Branching out: mechanisms of dendritic arborization . Nature Reviews Neuroscience, 11(5), 316-328. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1038/nrn2836 OpenAlex: https://openalex.org/W2065943966
    Crossref OpenAlex OpenCitations
  39. Ruth Simon , Heike Brylka , Herbert Schwegler , Sathish Venkataramanappa , Jacqueline Andratschke , Christoph Wiegreffe et al. (2012). A dual function of Bcl11b/Ctip2 in hippocampal neurogenesis . The EMBO Journal, 31(13), 2922-2936. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1038/emboj.2012.142 OpenAlex: https://openalex.org/W2124675599
    Crossref OpenAlex OpenCitations
  40. Zachary F. Mainen , Terrence J. Sejnowski (1996). Influence of dendritic structure on firing pattern in model neocortical neurons . Nature, 382(6589), 363-366. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1038/382363a0 OpenAlex: https://openalex.org/W2004921550
    Crossref OpenAlex OpenCitations
  41. Peter Penzes , Michael E Cahill , Kelly A Jones , Jon-Eric VanLeeuwen , Kevin M Woolfrey (2011). Dendritic spine pathology in neuropsychiatric disorders . Nature Neuroscience, 14(3), 285-293. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1038/nn.2741 OpenAlex: https://openalex.org/W2040268226
    Crossref OpenAlex OpenCitations
  42. R.J Tolwani , P.S Buckmaster , S Varma , J.M Cosgaya , Y Wu , C Suri et al. (2002). BDNF overexpression increases dendrite complexity in hippocampal dentate gyrus . Neuroscience, 114(3), 795-805. Elsevier BV.
    Type: Article DOI: 10.1016/s0306-4522(02)00301-9 OpenAlex: https://openalex.org/W2072182951
    Crossref OpenAlex OpenCitations
  43. G. V. Raymond , Margaret Bauman , Thomas L. Kemper (1995). Hippocampus in autism: a Golgi analysis . Acta Neuropathologica, 91(1), 117-119. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1007/s004010050401 OpenAlex: https://openalex.org/W2081713212
    Crossref OpenAlex OpenCitations
  44. Se Hoon Choi , Yun Li , Luis F Parada , Sangram S Sisodia (2009). Regulation of hippocampal progenitor cell survival, proliferation and dendritic development by BDNF . Molecular Neurodegeneration, 4(1), 52. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1186/1750-1326-4-52 OpenAlex: https://openalex.org/W2146726649
    Crossref OpenAlex OpenCitations
  45. David M. Feliciano , Tiffany V. Lin , Nathaniel W. Hartman , Christopher M. Bartley , Cathryn Kubera , Lawrence Hsieh et al. (2013). A circuitry and biochemical basis for tuberous sclerosis symptoms: from epilepsy to neurocognitive deficits . International Journal of Developmental Neuroscience, 31(7), 667-678. Wiley.
    Type: Article DOI: 10.1016/j.ijdevneu.2013.02.008 OpenAlex: https://openalex.org/W2028673844
    Crossref OpenAlex OpenCitations
  46. Jason J. Wolff , Guido Gerig , John D. Lewis , Takahiro Soda , Martin A. Styner , Clement Vachet et al. (2015). Altered corpus callosum morphology associated with autism over the first 2 years of life . Brain, 138(7), 2046-2058. Oxford University Press (OUP).
    Type: Article DOI: 10.1093/brain/awv118 10.17615/jbw1-3391
    OpenCitations
  47. Chang-Hyuk Kwon , Bryan W. Luikart , Craig M. Powell , Jing Zhou , Sharon A. Matheny , Wei Zhang et al. (2006). Pten Regulates Neuronal Arborization and Social Interaction in Mice . Neuron, 50(3), 377-388. Elsevier BV.
    Type: Article DOI: 10.1016/j.neuron.2006.03.023 OpenAlex: https://openalex.org/W2057308155
    Crossref OpenAlex OpenCitations
  48. Sabrina Davis , Serge Laroche (2006). Mitogen‐activated protein kinase/extracellular regulated kinase signalling and memory stabilization: a review . Genes, Brain and Behavior, 5(s2), 61-72. Wiley.
    Type: Article DOI: 10.1111/j.1601-183x.2006.00230.x OpenAlex: https://openalex.org/W2013045480
    Crossref OpenAlex OpenCitations
  49. Henk Roelink (2000). Hippocampus formation: An intriguing collaboration . Current Biology, 10(7), R279-R281. Elsevier BV.
    Type: Article DOI: 10.1016/s0960-9822(00)00407-3 OpenAlex: https://openalex.org/W2031511475
    Crossref OpenAlex OpenCitations
  50. Ksenia Z. Meyza , Erwin B. Defensor , Ashley L. Jensen , Michael J. Corley , Brandon L. Pearson , Roger L.H. Pobbe et al. (2013). The BTBR T+tf/J mouse model for autism spectrum disorders–in search of biomarkers . Behavioural Brain Research, 251, 25-34. Elsevier BV.
    Type: Article DOI: 10.1016/j.bbr.2012.07.021 OpenAlex: https://openalex.org/W2013997760
    Crossref OpenAlex OpenCitations
  51. Deepak P. Srivastava , Kevin M. Woolfrey , Kelly A. Jones , Charles T. Anderson , Katharine R. Smith , Theron A. Russell et al. (2012). An Autism-Associated Variant of Epac2 Reveals a Role for Ras/Epac2 Signaling in Controlling Basal Dendrite Maintenance in Mice . PLoS Biology, 10(6), e1001350. Public Library of Science (PLoS).
    Type: Article DOI: 10.1371/journal.pbio.1001350 OpenAlex: https://openalex.org/W2081272302
    Crossref OpenAlex OpenCitations
  52. Andrew R. Vaillant , Patrizia Zanassi , Gregory S. Walsh , Anne Aumont , Angel Alonso , Freda D. Miller (2002). Signaling Mechanisms Underlying Reversible, Activity-Dependent Dendrite Formation . Neuron, 34(6), 985-998. Elsevier BV.
    Type: Article DOI: 10.1016/s0896-6273(02)00717-1 OpenAlex: https://openalex.org/W2031863862
    Crossref OpenAlex OpenCitations
  53. S MOY , J NADLER , N YOUNG , A PEREZ , L HOLLOWAY , R BARBARO et al. (2007). Mouse behavioral tasks relevant to autism: Phenotypes of 10 inbred strains . Behavioural Brain Research, 176(1), 4-20. Elsevier BV.
    Type: Article DOI: 10.1016/j.bbr.2006.07.030 OpenAlex: https://openalex.org/W2016411894
    Crossref OpenAlex OpenCitations
  54. Longbo Zhang , Christopher M. Bartley , Xuan Gong , Lawrence S. Hsieh , Tiffany V. Lin , David M. Feliciano et al. (2014). MEK-ERK1/2-Dependent FLNA Overexpression Promotes Abnormal Dendritic Patterning in Tuberous Sclerosis Independent of mTOR . Neuron, 84(1), 78-91. Elsevier BV.
    Type: Article DOI: 10.1016/j.neuron.2014.09.009 OpenAlex: https://openalex.org/W2130791251
    Crossref OpenAlex OpenCitations
  55. Emily L. Casanova * , Imke A. J. van Kooten , Andrew E. Switala , Herman van Engeland , Helmut Heinsen , Harry W. M. Steinbusch et al. (2006). Minicolumnar abnormalities in autism . Acta Neuropathologica, 112(3), 287-303. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1007/s00401-006-0085-5 OpenAlex: https://openalex.org/W2054390925
    Crossref OpenAlex OpenCitations
  56. Brian Raught , Anne-Claude Gingras (1999). eIF4E activity is regulated at multiple levels . The International Journal of Biochemistry & Cell Biology, 31(1), 43-57. Elsevier BV.
    Type: Article DOI: 10.1016/s1357-2725(98)00131-9 OpenAlex: https://openalex.org/W2018500072
    Crossref OpenAlex OpenCitations
  57. Pat Levitt , Daniel B. Campbell (2009). The genetic and neurobiologic compass points toward common signaling dysfunctions in autism spectrum disorders . Journal of Clinical Investigation, 119(4), 747-754. American Society for Clinical Investigation.
    Type: Article DOI: 10.1172/jci37934 OpenAlex: https://openalex.org/W2018736722
    Crossref OpenAlex OpenCitations
  58. Jerzy Wegiel , Michael Flory , Izabela Kuchna , Krzysztof Nowicki , Shuang Yong Ma , Humi Imaki et al. (2014). Stereological study of the neuronal number and volume of 38 brain subdivisions of subjects diagnosed with autism reveals significant alterations restricted to the striatum, amygdala and cerebellum . Acta Neuropathologica Communications, 2(1), 141. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1186/s40478-014-0141-7 OpenAlex: https://openalex.org/W2140790453
    Crossref OpenAlex OpenCitations
  59. Joseph Vithayathil , Joanna Pucilowska , L. Henry Goodnough , Radhika P. Atit , Gary E. Landreth (2015). Dentate Gyrus Development Requires ERK Activity to Maintain Progenitor Population and MAPK Pathway Feedback Regulation . The Journal of Neuroscience, 35(17), 6836-6848. Society for Neuroscience.
    Type: Article DOI: 10.1523/jneurosci.4196-14.2015 OpenAlex: https://openalex.org/W2018956566
    Crossref OpenAlex OpenCitations
  60. Katherine D. Blizinsky , Blanca Diaz-Castro , Marc P. Forrest , Britta Schürmann , Anthony P. Bach , Maria Dolores Martin-de-Saavedra et al. (2016). Reversal of dendritic phenotypes in 16p11.2 microduplication mouse model neurons by pharmacological targeting of a network hub . Proceedings of the National Academy of Sciences, 113(30), 8520-8525. National Academy of Sciences.
    Type: Article DOI: 10.1073/pnas.1607014113 OpenAlex: https://openalex.org/W2465467919
    Crossref OpenAlex OpenCitations
  61. J. Pucilowska , P. A. Puzerey , J. C. Karlo , R. F. Galan , G. E. Landreth (2012). Disrupted ERK Signaling during Cortical Development Leads to Abnormal Progenitor Proliferation, Neuronal and Network Excitability and Behavior, Modeling Human Neuro-Cardio-Facial-Cutaneous and Related Syndromes . Journal of Neuroscience, 32(25), 8663-8677. Society for Neuroscience.
    Type: Article DOI: 10.1523/jneurosci.1107-12.2012 OpenAlex: https://openalex.org/W2165890492
    Crossref OpenAlex OpenCitations
  62. Alan D. Workman , Christine J. Charvet , Barbara Clancy , Richard B. Darlington , Barbara L. Finlay (2013). Modeling Transformations of Neurodevelopmental Sequences across Mammalian Species . The Journal of Neuroscience, 33(17), 7368-7383. Society for Neuroscience.
    Type: Article DOI: 10.1523/jneurosci.5746-12.2013 OpenAlex: https://openalex.org/W2022567100
    Crossref OpenAlex OpenCitations
  63. Longbo Zhang , David M. Feliciano , Tianxiang Huang , Shiliang Zhang , Angélique Bordey (2016). Hypoxia-inducible factor-1a contributes to dendritic overgrowth in tuberous sclerosis . Neuroscience Letters, 612, 43-47. Elsevier BV.
    Type: Article DOI: 10.1016/j.neulet.2015.11.038 OpenAlex: https://openalex.org/W2188556878
    Crossref OpenAlex OpenCitations
  64. Joan M. Jasien , Caitlin M. Daimon , Rui Wang , Bruce K. Shapiro , Bronwen Martin , Stuart Maudsley (2014). The effects of aging on the BTBR mouse model of autism spectrum disorder . Frontiers in Aging Neuroscience, 6, 225. Frontiers Media SA.
    Type: Article DOI: 10.3389/fnagi.2014.00225 OpenAlex: https://openalex.org/W2147068455
    Crossref OpenAlex OpenCitations
  65. Joanna Pucilowska , Joseph Vithayathil , Emmanuel J. Tavares , Caitlin Kelly , J. Colleen Karlo , Gary E. Landreth (2015). The 16p11.2 Deletion Mouse Model of Autism Exhibits Altered Cortical Progenitor Proliferation and Brain Cytoarchitecture Linked to the ERK MAPK Pathway . The Journal of Neuroscience, 35(7), 3190-3200. Society for Neuroscience.
    Type: Article DOI: 10.1523/jneurosci.4864-13.2015 OpenAlex: https://openalex.org/W2023621960
    Crossref OpenAlex OpenCitations
  66. A.Kimberley McAllister , Lawrence C. Katz , Donald C. Lo (1997). Opposing Roles for Endogenous BDNF and NT-3 in Regulating Cortical Dendritic Growth . Neuron, 18(5), 767-778. Elsevier BV.
    Type: Article DOI: 10.1016/s0896-6273(00)80316-5 OpenAlex: https://openalex.org/W2054595326
    Crossref OpenAlex OpenCitations
  67. Jacek Jaworski , Samantha Spangler , Daniel P. Seeburg , Casper C. Hoogenraad , Morgan Sheng (2005). Control of Dendritic Arborization by the Phosphoinositide-3′-Kinase–Akt–Mammalian Target of Rapamycin Pathway . The Journal of Neuroscience, 25(49), 11300-11312. Society for Neuroscience.
    Type: Article DOI: 10.1523/jneurosci.2270-05.2005 OpenAlex: https://openalex.org/W2044161108
    Crossref OpenAlex OpenCitations
  68. Emily L. Casanova * , Daniel P. Buxhoeveden , Andrew E. Switala , Emil Roy (2002). Neuronal Density and Architecture (Gray Level Index) in the Brains of Autistic Patients . Journal of Child Neurology, 17(7), 515-521. SAGE Publications.
    Type: Article DOI: 10.1177/088307380201700708 OpenAlex: https://openalex.org/W2025090265
    Crossref OpenAlex OpenCitations
  69. Mary M. Niblock , Judy K. Brunso-Bechtold , David R. Riddle (2000). Insulin-like growth factor I stimulates dendritic growth in primary somatosensory cortex . The Journal of neuroscience: the official journal of the Society for Neuroscience, 20(11), 4165. Society for Neuroscience.
    Type: Article DOI: 10.1523/jneurosci.20-11-04165.2000 OpenAlex: https://openalex.org/W2144132729
    Crossref OpenAlex
  70. Mariana Alonso , Jorge H. Medina , Lucas Pozzo-Miller (2004). ERK1/2 Activation Is Necessary for BDNF to Increase Dendritic Spine Density in Hippocampal CA1 Pyramidal Neurons . Learning & Memory, 11(2), 172-178. Cold Spring Harbor Laboratory.
    Type: Prépublication DOI: 10.1101/lm.67804 OpenAlex: https://openalex.org/W2138910339
    Crossref OpenAlex OpenCitations
  71. John M. Wang , Kami Koldewyn , Ryu-ichiro Hashimoto , Andrea Schneider , Lien Le , Flora Tassone et al. (2012). Male Carriers of the FMR1 Premutation Show Altered Hippocampal-Prefrontal Function During Memory Encoding . Frontiers in Human Neuroscience, 6, 297. Frontiers Media SA.
    Type: Article DOI: 10.3389/fnhum.2012.00297 OpenAlex: https://openalex.org/W2127480370
    Crossref OpenAlex OpenCitations
  72. Malgorzata Urbanska , Agata Gozdz , Lukasz J. Swiech , Jacek Jaworski (2012). Mammalian Target of Rapamycin Complex 1 (mTORC1) and 2 (mTORC2) Control the Dendritic Arbor Morphology of Hippocampal Neurons . Journal of Biological Chemistry, 287(36), 30240-30256. Elsevier BV.
    Type: Article DOI: 10.1074/jbc.m112.374405 OpenAlex: https://openalex.org/W2080946765
    Crossref OpenAlex OpenCitations
  73. Christos G. Gkogkas , Arkady Khoutorsky , Israeli Ran , Emmanouil Rampakakis , Tatiana Nevarko , Daniel B. Weatherill et al. (2013). Autism-related deficits via dysregulated eIF4E-dependent translational control . Nature, 493(7432), 371-377. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1038/nature11628 OpenAlex: https://openalex.org/W2048862315
    Crossref OpenAlex OpenCitations
  74. Thomas W Frazier , Antonio Y. Hardan (2009). A Meta-Analysis of the Corpus Callosum in Autism . Biological Psychiatry, 66(10), 935-941. Elsevier BV.
    Type: Article DOI: 10.1016/j.biopsych.2009.07.022 OpenAlex: https://openalex.org/W2030458571
    Crossref OpenAlex OpenCitations
  75. Seungshin Ha , Lori Redmond (2008). ERK mediates activity dependent neuronal complexity via sustained activity and CREB‐mediated signaling . Developmental Neurobiology, 68(14), 1565-1579. Wiley.
    Type: Article DOI: 10.1002/dneu.20682 OpenAlex: https://openalex.org/W2067478068
    Crossref OpenAlex OpenCitations
  76. David G. Amaral , Cynthia Mills Schumann , Christine Wu Nordahl (2008). Neuroanatomy of autism . Trends in Neurosciences, 31(3), 137-145. Elsevier BV.
    Type: Article DOI: 10.1016/j.tins.2007.12.005 OpenAlex: https://openalex.org/W2129179498
    Crossref OpenAlex OpenCitations
  77. Gareth M. Thomas , Richard L. Huganir (2004). MAPK cascade signalling and synaptic plasticity . Nature Reviews Neuroscience, 5(3), 173-183. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1038/nrn1346 OpenAlex: https://openalex.org/W2075361934
    Crossref OpenAlex OpenCitations
  78. Peter MacPherson , Ruth McGaffigan , Douglas Wahlsten , Peter V. Nguyen (2008). Impaired fear memory, altered object memory and modified hippocampal synaptic plasticity in split-brain mice . Brain Research, 1210, 179-188. Elsevier BV.
    Type: Article DOI: 10.1016/j.brainres.2008.03.008 OpenAlex: https://openalex.org/W2051464199
    Crossref OpenAlex OpenCitations
  79. Tiago A Ferreira , Arne V Blackman , Julia Oyrer , Sriram Jayabal , Andrew J Chung , Alanna J Watt et al. (2014). Neuronal morphometry directly from bitmap images . Nature Methods, 11(10), 982-984. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1038/nmeth.3125 OpenAlex: https://openalex.org/W2037200077
    Crossref OpenAlex OpenCitations
  80. Kami Koldewyn , David Hessl , John Adams , Flora Tassone , Paul J. Hagerman , Randi J. Hagerman et al. (2008). Reduced Hippocampal Activation During Recall is Associated with Elevated FMR1 mRNA and Psychiatric Symptoms in Men with the Fragile X Premutation . Brain Imaging and Behavior, 2(2), 105-116. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1007/s11682-008-9020-9 OpenAlex: https://openalex.org/W2095239381
    Crossref OpenAlex OpenCitations
  81. Andre S. Ribeiro , Brenda A. Eales , Fred G. Biddle (2013). Short-term and long-term memory deficits in handedness learning in mice with absent corpus callosum and reduced hippocampal commissure . Behavioural Brain Research, 245, 145-151. Elsevier BV.
    Type: Article DOI: 10.1016/j.bbr.2013.02.021 OpenAlex: https://openalex.org/W2045089157
    Crossref OpenAlex OpenCitations
  82. Haijie Yang , Sung-Oh Huh , Jae Seung Hong (2015). Enhancement of Short-Term Memory by Methyl-6-(Phenylethynyl)-Pyridine in the BTBR T+tf/J Mouse Model of Autism Spectrum Disorder . Endocrinology and Metabolism, 30(1), 98. Korean Endocrine Society.
    Type: Article DOI: 10.3803/enm.2015.30.1.98 OpenAlex: https://openalex.org/W2047666501
    Crossref OpenAlex OpenCitations
  83. Hadara Rubinfeld , Rony Seger (2005). The ERK Cascade: A Prototype of MAPK Signaling . Molecular Biotechnology, 31(2), 151-174. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1385/mb:31:2:151 OpenAlex: https://openalex.org/W2331692240
    Crossref OpenAlex OpenCitations
  84. Shao Jun Tang , Gerald Reis , Hyejin Kang , Anne-Claude Gingras , Nahum Sonenberg , Erin M. Schuman (2002). A rapamycin-sensitive signaling pathway contributes to long-term synaptic plasticity in the hippocampus . Proceedings of the National Academy of Sciences, 99(1), 467-472. National Academy of Sciences.
    Type: Article DOI: 10.1073/pnas.012605299 OpenAlex: https://openalex.org/W2056994440
    Crossref OpenAlex OpenCitations
  85. Douglas Wahlsten , Pamela Metten , John C. Crabbe (2003). Survey of 21 inbred mouse strains in two laboratories reveals that BTBR T/+ tf/tf has severely reduced hippocampal commissure and absent corpus callosum . Brain Research, 971(1), 47-54. Elsevier BV.
    Type: Article DOI: 10.1016/s0006-8993(03)02354-0 OpenAlex: https://openalex.org/W2052072017
    Crossref OpenAlex OpenCitations
  86. Jacob Ellegood , Brooke A. Babineau , R. Mark Henkelman , Jason P. Lerch , Jacqueline N. Crawley (2013). Neuroanatomical analysis of the BTBR mouse model of autism using magnetic resonance imaging and diffusion tensor imaging . NeuroImage, 70, 288-300. Elsevier BV.
    Type: Article DOI: 10.1016/j.neuroimage.2012.12.029 OpenAlex: https://openalex.org/W2096358139
    Crossref OpenAlex OpenCitations
  87. Luca Dodero , Mario Damiano , Alberto Galbusera , Angelo Bifone , Sotirios A. Tsaftsaris , Maria Luisa Scattoni et al. (2013). Neuroimaging Evidence of Major Morpho-Anatomical and Functional Abnormalities in the BTBR T+TF/J Mouse Model of Autism . PLoS ONE, 8(10), e76655. Public Library of Science (PLoS).
    Type: Article DOI: 10.1371/journal.pone.0076655 OpenAlex: https://openalex.org/W2099440139
    Crossref OpenAlex OpenCitations
  88. Eric Courchesne , Karen Pierce (2005). Why the frontal cortex in autism might be talking only to itself: local over-connectivity but long-distance disconnection . Current Opinion in Neurobiology, 15(2), 225-230. Elsevier BV.
    Type: Article DOI: 10.1016/j.conb.2005.03.001 OpenAlex: https://openalex.org/W2131541104
    Crossref OpenAlex OpenCitations
  89. Flora M. Vaccarino , Elena L. Grigorenko , Karen Müller Smith , Hanna E. Stevens (2009). Regulation of Cerebral Cortical Size and Neuron Number by Fibroblast Growth Factors: Implications for Autism . Journal of Autism and Developmental Disorders, 39(3), 511-520. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1007/s10803-008-0653-8 OpenAlex: https://openalex.org/W2060110575
    Crossref OpenAlex OpenCitations
  90. H. G. McFarlane , G. K. Kusek , M. Yang , J. L. Phoenix , V. J. Bolivar , J. N. Crawley (2008). Autism‐like behavioral phenotypes in BTBR T+tf/J mice . Genes, Brain and Behavior, 7(2), 152-163. Wiley.
    Type: Article DOI: 10.1111/j.1601-183x.2007.00330.x OpenAlex: https://openalex.org/W2071797996
    Crossref OpenAlex OpenCitations
  91. Ning Cheng , L. Bai , E. Steuer , L. Belluscio (2013). Olfactory Functions Scale with Circuit Restoration in a Rapidly Reversible Alzheimer's Disease Model . Journal of Neuroscience, 33(30), 12208-12217. Society for Neuroscience.
    Type: Article DOI: 10.1523/jneurosci.0291-13.2013 OpenAlex: https://openalex.org/W2105371361
    Crossref OpenAlex OpenCitations
  92. Cortney A. Turner , Stanley J. Watson , Huda Akil (2012). The Fibroblast Growth Factor Family: Neuromodulation of Affective Behavior . Neuron, 76(1), 160-174. Elsevier BV.
    Type: Article DOI: 10.1016/j.neuron.2012.08.037 OpenAlex: https://openalex.org/W2063710526
    Crossref OpenAlex OpenCitations
  93. Wen‐Liang Zhou , Ping Yan , Joseph P. Wuskell , Leslie M. Loew , Srdjan D. Antic (2008). Dynamics of action potential backpropagation in basal dendrites of prefrontal cortical pyramidal neurons . European Journal of Neuroscience, 27(4), 923-936. Wiley.
    Type: Article DOI: 10.1111/j.1460-9568.2008.06075.x OpenAlex: https://openalex.org/W2064305397
    Crossref OpenAlex OpenCitations
  94. Emily L. Casanova * , Ayman S El-Baz , Shweta S Kamat , Brynn A. Dombroski , Fahmi Khalifa , Ahmed Elnakib et al. (2013). Focal cortical dysplasias in autism spectrum disorders . Acta Neuropathologica Communications, 1(1), 67. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1186/2051-5960-1-67 OpenAlex: https://openalex.org/W2155740914
    Crossref OpenAlex OpenCitations
  95. Rich Stoner , Maggie L. Chow , Maureen P. Boyle , Susan M. Sunkin , Peter R. Mouton , Subhojit Roy et al. (2014). Patches of Disorganization in the Neocortex of Children with Autism . New England Journal of Medicine, 370(13), 1209-1219. Massachusetts Medical Society.
    Type: Article DOI: 10.1056/nejmoa1307491 OpenAlex: https://openalex.org/W2142438562
    Crossref OpenAlex OpenCitations
  96. Dalila Pinto , Elsa Delaby , Daniele Merico , Mafalda Barbosa , Alison Merikangas , Lambertus Klei et al. (2014). Convergence of Genes and Cellular Pathways Dysregulated in Autism Spectrum Disorders . The American Journal of Human Genetics, 94(5), 677-694. Elsevier BV.
    Type: Article DOI: 10.1016/j.ajhg.2014.03.018 OpenAlex: https://openalex.org/W2129867386
    Crossref OpenAlex OpenCitations
  97. Ya Wen , Mohamad J. Alshikho , Martha R. Herbert (2016). Pathway Network Analyses for Autism Reveal Multisystem Involvement, Major Overlaps with Other Diseases and Convergence upon MAPK and Calcium Signaling . PLOS ONE, 11(4), e0153329. Public Library of Science (PLoS).
    Type: Article DOI: 10.1371/journal.pone.0153329 OpenAlex: https://openalex.org/W2330196942
    Crossref OpenAlex OpenCitations
  98. Michelle R. Lyons , Anne E. West (2011). Mechanisms of specificity in neuronal activity-regulated gene transcription . Progress in Neurobiology, 94(3), 259-295. Elsevier BV.
    Type: Article DOI: 10.1016/j.pneurobio.2011.05.003 OpenAlex: https://openalex.org/W2135241917
    Crossref OpenAlex OpenCitations
  99. M Neves-Pereira , B Müller , D Massie , Justin H. G. Williams , P C M O’Brien , A Hughes et al. (2009). Deregulation of EIF4E: a novel mechanism for autism . Journal of Medical Genetics, 46(11), 759-765. BMJ.
    Type: Article DOI: 10.1136/jmg.2009.066852 OpenAlex: https://openalex.org/W2097231159
    Crossref OpenAlex OpenCitations
  100. (s. d.). Amaral DG, Lavenex P. The Hippocampus Book. 2007:37–114.
    Type: Autre
    Crossref
  101. Ning Cheng , Maryam Khanbabaei , Kartikeya Murari , Jong M. Rho (2017). Disruption of visual circuit formation and refinement in a mouse model of autism . Autism Research, 10(2), 212-223. Wiley.
    Type: Article DOI: 10.1002/aur.1687 OpenAlex: https://openalex.org/W2518168428
    Crossref OpenAlex OpenCitations
  102. Alireza Faridar , Dorothy Jones-Davis , Eric Rider , Jiang Li , Ilan Gobius , Laura Morcom et al. (2014). Mapk/Erk activation in an animal model of social deficits shows a possible link to autism . Molecular Autism, 5(1), 57. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1186/2040-2392-5-57 OpenAlex: https://openalex.org/W2111840774
    Crossref OpenAlex OpenCitations
  103. Thomas A Lanz , Edward Guilmette , Mark M Gosink , James E Fischer , Lawrence W Fitzgerald , Diane T Stephenson et al. (2013). Transcriptomic analysis of genetically defined autism candidate genes reveals common mechanisms of action . Molecular Autism, 4(1), 45. Springer Science and Business Media LLC.
    Type: Article DOI: 10.1186/2040-2392-4-45 OpenAlex: https://openalex.org/W2138002108
    Crossref OpenAlex OpenCitations
  104. Jason J. Wolff , Guido Gerig , John D. Lewis , Takahiro Soda , Martin A. Styner , Clement Vachet et al. (2015). Altered corpus callosum morphology associated with autism over the first 2 years of life . Brain: a journal of neurology, 138(Pt 7), 2046. Oxford University Press (OUP).
    Type: Article DOI: 10.1093/brain/awv118 OpenAlex: https://openalex.org/W2157875253
    Crossref OpenAlex
  105. J.A. Stockman (2013). Neuron Number and Size in Prefrontal Cortex of Children With Autism . Yearbook of Pediatrics, 2013, 395-397. Elsevier BV.
    Type: Article DOI: 10.1016/j.yped.2011.12.022 OpenAlex: https://openalex.org/W2320580054
    OpenAlex