Billets de Michelle Dawson

Billet publié sur Bluesky le 14/11/2025 12:33

Bluesky Publication avec DOI crossref Extrait cité dans le billet Lien intégré au billet Termes sur l’autisme

Assessing the literature, finding "serious flaws, inconsistencies, and contradictions that... undermine any claims about the involvement of the gut microbiome in autism" & "in many of the studies... some or all of the authors have competing commercial interests" www.cell.com/neuron/fullt... free

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Publication avec DOI Récupéré Publication crossref

Kevin J. Mitchell, Darren L. Dahly, Dorothy V.M. Bishop (2026). Conceptual and methodological flaws undermine claims of a link between the gut microbiome and autism. Neuron, 114(2), 196-211. Elsevier BV.

Date de publication
janvier 2026
Identifiant
10.1016/j.neuron.2025.10.006
Auteurs
Kevin J. Mitchell, Darren L. Dahly, Dorothy V.M. Bishop
Source
Neuron
Détails
114(2), 196-211
Type de référence
article
Éditeur
Elsevier BV
Source de métadonnées
crossref

Résumé

The idea that the gut microbiome causally contributes to autism has gained currency in the scientific literature and popular press. Support for this hypothesis comes from three lines of evidence: human observational studies, preclinical experiments in mice, and human clinical trials. We critically assessed this literature and found that it is beset by conceptual and methodological flaws and limitations that undermine claims that the gut microbiome is causally involved in the etiology or pathophysiology of autism.

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