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Post published on Twitter/X on 24 Dec 2013 00:13

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Thomas G. O'Connor, Jan A. Moynihan, Mary T. Caserta (2014). Annual Research Review: The neuroinflammation hypothesis for stress and psychopathology in children – developmental psychoneuroimmunology. Journal of Child Psychology and Psychiatry, 55(6), 615-631. Wiley.

Publication date
23 Dec 2013
Identifier
10.1111/jcpp.12187
Authors
Thomas G. O'Connor, Jan A. Moynihan, Mary T. Caserta
Source
Journal of Child Psychology and Psychiatry
Details
55(6), 615-631
Reference type
article
Publisher
Wiley
Metadata source
crossref

Abstract

Abstract Experimental animal and adult human data suggest that stress exposure is associated with alterations in immune system function that may underlie increased susceptibility to disease and behavioral disorders. The implications of these data for child psychology and psychiatry are not yet clear. The current review seeks to distil and translate the relevant animal and adult human work to children to advance a developmental model of psychoneuroimmunology. In addition to reviewing key specific findings, we consider biological/conceptual models and technical aspects of psychoneuroimmunology work in pediatric populations, and outline the rationales and advantages of integrating hypotheses concerning neuroinflammation in developmental studies of psychopathology.

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