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Sarah Schaubroeck, Ellen Demurie, Jannath Begum‐Ali, Sven Bölte, Sofie Boterberg, Jan Buitelaar, Tony Charman, Terje Falck‐Ytter, et al.
(2026).
The stability of the Autism Diagnostic Observation Schedule‐2 in children aged 14–36 months with elevated likelihood for autism.
Journal of Child Psychology and Psychiatry, 67(6), 869-880.
Wiley.
- Publication date
-
16 Nov 2025
- Identifier
-
10.1111/jcpp.70078
- Authors
-
Sarah Schaubroeck,
Ellen Demurie,
Jannath Begum‐Ali,
Sven Bölte,
Sofie Boterberg,
Jan Buitelaar,
Tony Charman,
Terje Falck‐Ytter,
Sabine Hunnius,
Mark H. Johnson,
Emily Jones,
Iris Oosterling,
Greg Pasco,
Mirjam Pijl,
Carlijn Van den Boomen,
Petra Warreyn,
Herbert Roeyers
- Source
- Journal of Child Psychology and Psychiatry
- Details
- 67(6), 869-880
- Reference type
- article
- Publisher
- Wiley
- Metadata source
- crossref
Abstract
Background This study investigated the stability of Autism Diagnostic Observation Schedule, Second Edition (ADOS ‐2) classifications in a cohort of 304 siblings at elevated likelihood for autism (EL ‐siblings). Methods ADOS ‐2 assessments were conducted at 14, 24 and 36 months, with Clinical Best Estimate (CBE ) autism diagnoses determined at 36 months. Results Our findings indicate that while some children have stable ADOS ‐2 classifications from early on, a significant proportion of the children show inconsistent classifications over time. The overall stability of ADOS ‐2 autism spectrum classifications increased from 14 to 36 months and agreement with CBE autism clinical diagnosis was moderate and increased with age. Conclusions Caution is warranted when interpreting individual ADOS ‐2 results, as they should always complement, and can never replace, a comprehensive clinical evaluation. These findings highlight the importance of continued follow‐up beyond 14 months in young EL ‐children, a group for whom early assessment may be both feasible and beneficial and emphasises the need to integrate multiple assessment measures and multiple informants for accurate early autism identification.
Study authors in this cited reference