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Post published on Twitter/X on 29 Dec 2021 12:36

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James McKowen, Diana Woodward, Amy M. Yule, Maura DiSalvo, Vinod Rao, Julia Greenbaum, Gagan Joshi, Timothy E. Wilens (2022). Characterizing autistic traits in treatment‐seeking young adults with substance use disorders. The American Journal on Addictions, 31(2), 108-114. Wiley.

Publication date
26 Dec 2021
Identifier
10.1111/ajad.13247
Authors
James McKowen, Diana Woodward, Amy M. Yule, Maura DiSalvo, Vinod Rao, Julia Greenbaum, Gagan Joshi, Timothy E. Wilens
Source
The American Journal on Addictions
Details
31(2), 108-114
Reference type
article
Publisher
Wiley
Metadata source
crossref

Abstract

Abstract Background and Objectives Recent work highlights an increase in the overlap of autism spectrum disorder (ASD) and substance use disorder (SUD). Little is known about the presence of ASD symptoms in SUD‐treatment‐seeking populations. Methods The informant‐rated Social Responsiveness Scale‐2 (SRS‐2) was completed at intake to an outpatient SUD clinic for youth aged 16–26 (N = 69). Comparisons were made between those with elevated SRS‐2 scores on demographic, psychiatric, and substance use variables. Results Parents of sixty‐nine patients with SUD completed the SRS‐2. Fourteen (20%) (average age 18.7 ± 2.5) had elevated SRS‐2 Total T‐scores (≥66) and 55 (average age 18.1 ± 2.8) had non‐clinical SRS‐2 Total T‐scores. There were few differences between groups; however, those with elevated SRS‐2 Total T‐scores were more likely to have a stimulant use disorder (odds ratio [OR] = 7.59, 95% confidence interval [CI] = 0.77, 101.88; p = 0.05) or an opioid use disorder (OR = 5.02, 95% CI = 0.59, 43.27; p = 0.08) than patients with normal SRS‐2 Total T‐scores as well as alcohol use in the week prior to intake. Discussion and Conclusions A significant proportion of treatment‐seeking SUD outpatients suffer from clinically elevated autistic traits. These findings highlight the importance of assessing for autistic traits in SUD treatment settings yet additional research is needed to determine if these findings are specific to the presence of ASD or secondary to sequelae of specific SUD presentations. Scientific Significance This study is, to our knowledge, the first to have examined the prevalence, morbidity, or clinical characteristics, associated with ASD symptoms in a SUD‐specific population.

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