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David Mason, Simone J. Capp, Gavin R. Stewart, Matthew J. Kempton, Karen Glaser, Patricia Howlin, Francesca Happé
(2021).
A Meta-analysis of Outcome Studies of Autistic Adults: Quantifying Effect Size, Quality, and Meta-regression.
Journal of Autism and Developmental Disorders, 51(9), 3165-3179.
Springer Science and Business Media LLC.
- Publication date
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17 Nov 2020
- Identifier
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10.1007/s10803-020-04763-2
- Authors
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David Mason,
Simone J. Capp,
Gavin R. Stewart,
Matthew J. Kempton,
Karen Glaser,
Patricia Howlin,
Francesca Happé
- Source
- Journal of Autism and Developmental Disorders
- Details
- 51(9), 3165-3179
- Reference type
- article
- Publisher
- Springer Science and Business Media LLC
- Metadata source
- crossref
Abstract
Abstract Longitudinal studies have generally reported poor outcomes in adulthood for the majority of individuals (c.50–60%) with autism. Several factors putatively predict outcome (e.g. IQ), but findings remain mixed. This paper presents an updated meta-analysis of autism outcome studies and extends previous findings with additional analyses (including meta-regression). A total of 4088 records was screened and 18 studies, involving 1199 individuals, were included in the quantitative analysis. Estimated percentages indicated that 20.0% of participants were rated as having a good outcome, 26.6% a fair outcome, and 49.3% a poor outcome. Meta-regression indicated that lower IQ in adulthood was predictive of poor outcome; other meta-regression models did not survive correction for multiple comparisons. Overall, outcomes for autistic people are on average poor, and higher IQ appears to be protective against having a poor outcome. The limitations of current constructs of outcome are discussed.
Study authors in this cited reference